9 research outputs found
Analytical and Experimental Vibration Analysis of Glass Fibre Reinforced Polymer Composite Beam
No full textThe aim of this work is to investigate analytical and experimental vibration of composite beam. The composite beam is used as composite footbridge model prototype which is assumed. For the dynamic test, hammer excitation is used to excite the beam at fixed locations. The modal parameters are extracted from the time response using a time domain analysis, i.e. the stochastic subspace identification technique. Finite element models for different boundary conditions are constructed using the commercial finite element software package ANSYS for natural frequencies of the beam to support and verify the dynamic measurements. The result obtained from analytical solution, dynamic tests and the FEM are presented and analysed.Oluseun Adediran, please contact the author email [email protected]
Informatics-Based Product-Service Systems for Point-of-Care Devices
No full textOrganised by: Cranfield UniversityInformatics related to point-of-care devices denotes the ability to translate stand-alone biological data into
meaningful information that can be interpreted to enable and support users in taking the most appropriate
steps to aid in managing their health. This paper considers small point-of-care devices used outside
healthcare environments, and presents glucometers as an example. The paper seeks to evaluate the
current level of servitization of point-of-care testing devices and considers whether they are, or could form,
the product-core of a product-service system. The type of product-service system, its informatics
requirements, and the services such a system could provide are also considered.Mori Seiki – The Machine Tool Company; BAE Systems; S4T – Support Service Solutions: Strategy and Transitio
Epidemiology of Prostate Cancer in NIGERIA: Observations at Lagos State University Teaching Hospital
No full textProstate cancer is a leading cause of morbidity and mortality among men, especially of African descent. Over the years, there has been relative paucity of research work on the subject of prostate cancer in sub-Saharan Africa. The objective of the study is to examine records of prostate cancers diagnosed at Mayo Height laboratory, Lagos State University Teaching Hospital, Lagos, Nigeria between January 2015 and June 2018, with a view to studying the epidemiological variables and pattern seen. Histopathological slides were retrieved and reviewed; relevant data were extracted from the Laboratory Information Systems, Laboratory Requisition Forms and the Hospital records where necessary. The data were statistically analysed. A total of 333 cases of prostate cancer were diagnosed during the study period, representing 46.4% of all prostate specimens received. The median age of the patients at diagnosis was 70 years, with the lowest recorded age being 50 years, while the highest age was 90 years. Individuals in the 7th decade of life (61-70 years) were the most commonly affected. Overwhelming number of cases (97.3%) were diagnosed based on trucut biopsy specimens, compared to open prostatectomy specimen. Majority of the cancers were histologically adenocarcinomas (97.3%) and majority of the tumours were of high grade (Gleason grade 5) representing 37.5%. Prostate cancer is an obvious scourge in Nigeria. It is commonly seen in the 7th decade of life. Majority of the patients had high grade adenocarcinoma.
 
Long-Term Effectiveness of Intradiscal Culture-Expanded Mesenchymal Stem Cells (MSCs) with Platelet Products for Discogenic Low Back Pain
No full textBackground/Objectives: Low back pain (LBP) remains one of the leading causes of disability globally and contributes significantly to healthcare expenditures. Discogenic LBP, a subtype stemming from intervertebral disc degeneration, often provesrefractory to conventional treatment modalities. Regenerative orthobiologic therapies, including platelet-rich plasma (PRP), platelet lysate (PL), and mesenchymal stem cells (MSCs), have emerged as promising alternatives, though long-term outcomes and safety profiles are not yet well understood. Methods: This case series reports 13 patients treated between 2015 and 2016 at an outpatient interventional pain center who received intradiscal culture-expanded MSC injections with or without additional injections to other surrounding vertebral structures. There was no control group. Inclusion required patients to have discogenic LBP with or without radiculopathy and at least six years of completed follow-up data. Outcomes were assessed using Numeric Rating Scale (NRS), Functional Rating Index (FRI), and modified Single Assessment Numeric Evaluation (SANE) scores at multiple time points up to 10 years post treatment. Results: Thirteen patients met the inclusion criteria. Significant reductions in NRS and FRI scores were observed at 6 months, 3 years, and 6 years (p < 0.01). At 6 years, the average NRS score decreased by 2.50 points, FRI by 24.14 points, and SANE showed a 60% improvement. At 10 years, among the seven patients who responded, average SANE improvement was 78.1%. No adverse events were reported. Conclusions: This study presents the longest known follow-up data for intradiscal MSC therapy for discogenic LBP, demonstrating sustained improvements in pain and function. These findings support further investigation into combination orthobiologic therapies as a viable long-term treatment option for chronic LBP
Pattern of Injuries in Fatal Motorcycle Accidents Seen in Lagos State University Teaching Hospital: An Autopsy-Based Study
No full textBACKGROUND: Deaths from motorcycle accident injuries have remained a major public health issue in Nigeria over the years.AIM: The study is to determine the age and gender distribution of the victims and to identify the cause of death and the anatomical pattern of injuries seen.METHODOLOGY: This is a 5-year autopsy-based study of all motorcycle accident deaths seen in Lagos State University Teaching Hospital between December 2009 and November 2014. The data were retrieved from autopsy reports, hospital case notes extracts from police diary and were analysed using SPSS version 20.RESULTS: Motorcycle accidents accounted for 156 (2.8%) of all the autopsies done (5,661), and 156 (18.4%) of all Road Traffic Accidents (RTA) autopsies (849) performed over the study period, with a male: female ratio of 6:1. The peak age of victims was 31-40 years (30.9%). Head injuries accounted for most (41.4%) of the injuries seen, and the majority of the victims died of craniocerebral injury 53 (50.7%).CONCLUSION: This study showed that males in the fourth decade of life are the major victims of motorcycle accident death. The majority of the victims were the rider of the motorcycle. Most of them died of the craniocerebral injury.</jats:p
Artificial neural network-based home energy management system for smart homes
No full textEnergy efficiency is widely recognized as one of the most significant and economical ways to lower greenhouse gas (GHG) emissions. The aims and goals are that smart meters can evaluate and communicate in-depth real-time electricity usage, enable remote real-time monitoring and management of power consumption, and provide consumers with real-time pricing and analyzed usage information. The house energy management controller decides which loads will be powered based on the real home energy demands and the predefined load priorities. Artificial intelligence (AI) is being used increasingly in control applications due to its great effectiveness and efficiency. As a result, in this work, the author designed, simulated, and optimized an artificial neural network-based model simulation framework that simulates a home with a variety of home appliances and optimizes the total energy consumption of the home realistically through intelligent control of home appliances. The MATLAB application was used to model and examine the performance of four common household appliances: the water heater (WH), washing machine (WM), air conditioner (AC), and refrigerator (RG). The result shows a considerable reduction and savings in energy consumption without a decrease in consumer comfort
Early Outcomes of Percutaneous Transvenous Transseptal Transcatheter Valve Implantation in Failed Bioprosthetic Mitral Valves, Ring Annuloplasty, and Severe Mitral Annular Calcification
No full textDual antiplatelet therapy duration after coronary stenting in clinical practice: results of an EAPCI survey
No full textAims: Our aim was to report on a survey initiated by the EuropeanAssociation of Percutaneous Cardiovascular Interventions (EAPCI) concerning opinion on the evidence relating to dual antiplatelet therapy (DAPT) duration after coronary stenting.Methods and results: Results from three randomised clinical trials were scheduled to be presented at the American Heart Association Scientific Sessions 2014 (ARIA 2014). A web-based survey was distributed to all individuals registered in the EuroIntervention mailing list (n=15,200) both before and after ARIA 2014. A total of 1,134 physicians responded to the first (i.e., before AHA 2014) and 542 to the second (i.e., after ARIA 2014) survey. The majority of respondents interpreted trial results consistent with a substantial equipoise regarding the benefits and risks of an extended versus a standard DAPT strategy. Two respondents out of ten believed extended DAFT should be implemented in selected patients. After ARIA 2014, 46.1% of participants expressed uncertainty about the available evidence on DAFT duration, and 40.0% the need for clinical guidance.Conclusions: This EAPCI survey highlights considerable uncertainty within the medical community with regard to the optimal duration of DAFT after coronary stenting in the light of recent reported trial results. Updated recommendations for practising physicians to guide treatment decisions in routine clinical practice should be provided by international societies
Dual antiplatelet therapy duration after coronary stenting in clinical practice: Results of an EAPCI survey
No full textAims: Our aim was to report on a survey initiated by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) concerning opinion on the evidence relating to dual antiplatelet therapy (DAPT) duration after coronary stenting. Methods and results: Results from three randomised clinical trials were scheduled to be presented at the American Heart Association Scientific Sessions 2014 (AHA 2014). A web-based survey was distributed to all individuals registered in the EuroIntervention mailing list (n=15,200) both before and after AHA 2014. A total of 1,134 physicians responded to the first (i.e., before AHA 2014) and 542 to the second (i.e., after AHA 2014) survey. The majority of respondents interpreted trial results consistent with a substantial equipoise regarding the benefits and risks of an extended versus a standard DAPT strategy. Two respondents out of ten believed extended DAPT should be implemented in selected patients. After AHA 2014, 46.1% of participants expressed uncertainty about the available evidence on DAPT duration, and 40.0% the need for clinical guidance. Conclusions: This EAPCI survey highlights considerable uncertainty within the medical community with regard to the optimal duration of DAPT after coronary stenting in the light of recent reported trial results. Updated recommendations for practising physicians to guide treatment decisions in routine clinical practice should be provided by international societies
