4,848 research outputs found
will-rowe/groot: v0.3
No full text<ul>
<li>retains reads that overlap start/end of a gene</li>
<li>adds --lowCov option to <code>groot report</code> subcommand</li>
<li>general readability improvements</li>
</ul>
will-rowe/groot: v0.8.3
No full text<ul>
<li>fixes minHash bug introduced at last release</li>
<li>adds minhash package tests</li>
<li>updates default indexing parameters</li>
</ul>
will-rowe/groot: v1.0.1
No full textMajor release which ports over dev work from baby-groot and fixes several GROOT issues. Apologies to users for taking so long to get around to this release! Summary:
LSH ensemble index - allows variable read length via containment search
Concurrency improvements - drastically reduces memory use and runtime
Improved tests
Minor bug fixes (like meaningful catches for empty input files etc)
ntHash for minhash
Go mod support
Improved handling of duplicate graph windows/sketches
Prepares codebase for EM on weighted graphs
Improved db distribution mechanis
will-rowe/hulk: v0.1.2
No full text<p>Minor bug fixes and improvements:</p>
<ul>
<li>adding buffered channels for read processing and hashing</li>
<li>swapping countmin sketch parameters (back to epsilon and delta to offer more tuning)</li>
<li>tweaking jump hash for counter placement in cms</li>
<li>updating default settings to improve performance after the above changes</li>
</ul>
The role of Plasmodium falciparum var genes in malaria in pregnancy
No full textSequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified
Introduction. Shakespeare: Overlapping Mediascapes in the Mind
No full textIntroduction to the issue 'Shakespeare in the Media. Old and New', Anglistica aion, 15.2, 2011, co-edited with co-author Katherine Rowe, discussing the place of Shakespeare in the media today and the 'state of the art' of Shakespeare studies on the topic
Letter from Sanford Rowe and W. W. Bass to Carl Hayden
No full textLetter from Sanford Rowe and W. W. Bass to Carl Hayden requesting a re-examination on the proposed park boundaries as they are disadvantageous to current land owners surrounding the canyon
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