126,159 research outputs found

    A. B. Wiles

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    Dr. A. B. Wiles is shown looking at plants in a greenhouse.https://scholarsjunction.msstate.edu/ua-photo-collection/6401/thumbnail.jp

    Wiles v. Wiles : Brief of Appellant

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    JOSKPH WILES, Plaintiff and Appellee. vs. JEAll B. WILES, Defendant and Appellant, ) 12-WTSCase Wo. 93*400 CA APPELLANT\u27S BRIEF Priority No

    Melbourne Express (to Sydney) hauled by locomotive 3673 near Flemington, Christmas 1939 [picture]

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    Part of collection: Buckland collection of railway transport photographs.; Title from inscription on reverse.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4543356

    Locomotive 2413 at Windsor, 26 November 1960 [picture]

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    Part of collection: Buckland collection of railway transport photographs.; Title from inscription on reverse.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4543357

    Directed evolution of an artificial cell lineage

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    Biological development is a complex process that mediates between genotypes, to which mutations occur, and phenotypes, on which selection acts. Properties of development can therefore have considerable impact on evolution. However, in many existing simulation models of development, the developmental process itself is difficult to recover and/or analyse. We have previously introduced a model of development in which the developmental process is represented as a cell lineage. Here we use this model to further explore the control of development, and the influence that development has on shaping an adaptive landscape

    Rugged NK landscapes contain the highest peaks

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    NK models provide a family of tunably rugged fitness landscapes used in a wide range of evolutionary computation studies. It is well known that the average height of local optima regresses to the mean of the landscape with increasing ruggedness, K. This fact has been confirmed with both theoretical studies of landscape structure and empirical studies of evolutionary search. However, we show mathematically that the global optimum behaves quite differently: the expected value of the global optimum is highest in the maximally rugged case. Furthermore, we demonstrate that this expected value increases with K, despite the fact that the average fitness of the local optima decreases. We find the asymptotic value of the global optimum as N approaches infinity for both the smooth and maximally rugged cases. We interpret these results in the context of evolutionary search, and describe the relationship between the global optimum, local optima and found optima as search effort is geometrically increased

    A comparison of neutral landscapes - NK, NKp and NKq

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    Recent research in molecular evolution has raised awareness of the importance of selective neutrality. Several different models of neutrality have been proposed based on Kauffman’s well-known NK landscape model. Two of these models, NKp and NKq, are investigated and found to display significantly different structural properties. The fitness distributions of these neutral landscapes reveal that their levels of correlation with non-neutral landscapes are significantly different, as are the distributions of neutral mutations. In this paper we describe a series of simulations of a hill climbing search algorithm on NK, NKp and NKq landscapes with varying levels of epistatic interaction. These simulations demonstrate differences in the way that epistatic interaction affects the 'searchability' of neutral landscapes. We conclude that the method used to implement neutrality has an impact on both the structure of the resulting landscapes and on the performance of evolutionary search algorithms on these landscapes. These model-dependent effects must be taken into consideration when modelling biological phenomena

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Deep learning-based insights on T:R ratio behaviour during prolonged screening for S-ICD eligibility

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    Dr. Mohamed ElRefai is receiving unrestricted grant from Boston Scientific. Dr. Benedict Wiles has received unrestricted research funding and consultancy payments from Boston Scientific. Dr. Paul Roberts receives consultancy fees from Boston Scientific and Medtronic. The other authors declare no competing interests.Peer reviewe

    Eupatrella bijani Wiles 1999

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    Eupatrella bijani Wiles, 1999 (Figs. 3 A–E) New records. 0/ 2 /0, Liwagu River at crossing with summit, Mt Kinabalu, Borneo, Malaysia, 6 º 01.868 N, 116 º 32.912 E, alt. 1919 m asl., 11 -ix- 2012; 0/ 1 /0, Small stream Layang Layang, Mt Kinabalu, 6 º 0 2.711 N 116 º 33.627 E, alt. 2697 m asl, 12 -ix- 2012. Description. Female (male unknown): As the original description lacks figures of chelicerae and gnathosoma, we give additional figures and measurements based on two females from Borneo (a larger, mature, and a juvenile [indicated by larger sclerite pores and a weaker sclerotization, see Figs. 3 A–B]). Measurements (mature specimen, in parentheses juvenile; [in square parentheses measurements from Wiles 1999])—Idiosoma (ventral view: Fig. 3 B) length 1390–1584 (1013) [460], width 988–1206 (700) [300]; distance between anterior tip of Cx-I and posterior margin of Cx-IV 759 (650); gonopore length/width 205 (194) [200]/ 166 (159). Capitulum length 258 (244) [141]; chelicera total length 489 (483), basal segment length 319 (305), claw length 185 (194), basal segment/claw length ratio 1.7 (1.57); Palp (Fig. 3 E): total length 415 [325], dorsal length/ height, dorsal length/height ratio: P1, 55/ 35, 1.6 [46 /-, -]; P2, 85/ 51, 1.68 (89 / 52, 1.7) [65 /-, -]; P3, 69/ 51.5, 1.34 (71 / 53, 1.34) [54 /-, -]; P 4, 157 / 37, 4.2 (152 / 40, 3.8) [130 /-, -]; P5, 49/ 16, 3.0 (48 / 28, 2.65) [30 /-, -]; length P 2 /P 4 ratio 0.54 (0.59) [0.5]. Legs: dorsal length of I-leg- 2–5: 131 (116), 116 (116) [78], 159 (158) [130], 180 (177) [95], 208 (197) [147]; dorsal length of IV-leg: 131 (131), 119 (116), 144 (144) [78], 297 (294) [260], 272 (269) [217], 259 (250) [183]. Remarks. The two female specimens from this study match the general morphology of Eupatrella bijani Wiles, 1999, described from S. Bersih, a tributary of the River Belalong in Brunei Darussalem. Wiles’ (1999) measurements of idiosoma (length 460, width 300) are in contradiction compared with the specimens in our study, but also with the gonopore length (200) in the original description. While the idiosoma size of our specimens exceed by more than 100 % dimensions given by Wiles (1999), the gonopore length is in good agreement with the original description. Most probably the measurements of idiosoma in Wiles (1999) are mistaken by a factor of about two. Distribution. Borneo (Wiles 1999, present study).Published as part of Smit, Harry & Pešić, Vladimir, 2014, Water mites from Mount Kinabalu and the Crocker Range, Borneo, Malaysia (Acari: Hydrachnidia), with the description of 34 new species, pp. 1-71 in Zootaxa 3876 (1) on page 9, DOI: 10.11646/zootaxa.3876.1.1, http://zenodo.org/record/28728
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