1,355,185 research outputs found

    Chemical analysis of WEX (ASH-WEX).

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    <p>(<b>A</b>, <b>B</b> and <b>D</b>) HPLC analysis of WEX under two different conditions showed that WEX has four major components (<b>B</b>) and minor amounts of withaferin A and withanone (<b>D</b>). Cell-based comparative shRNA-mediated loss-of-function viability analysis of i-Extract and WEX showing that these involve several common gene targets. Blue and Red color in the wells signify dead and live cells, respectively, as examined by Alamar Blue assay (<b>C</b>). (<b>E</b>) Examination of proteins in the WEX by SDS-PAGE and Coomassie Brilliant Blue staining showing six proteins that acted as a signature of WEX.</p

    Altering the emission behavior with the turn of a thiophene ring: The photophysics of condensed ring systems of alternating benzenes and thiophenes

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    Six aromatic compounds with embedded thiophenes differing in the number of rings (2-5) and thiophene orientation along the long axis of the molecule (syn, anti) were investigated. Photophysical properties, steady-state absorption, fluorescence, phosphorescence, lifetimes, quantum yields, and a comprehensive time-resolved spectroscopic analysis (femtosecond and nanosecond transient absorption spectroscopy) have been studied as a function of molecular structure. © 2006 American Chemical Society.Aaron JJ, 2002, J FLUORESC, V12, P231, DOI 10.1023-A:1016869002735; Abdel-Shafi AA, 2005, J PHOTOCH PHOTOBIO A, V172, P170, DOI 10.1016-j.photochem.2004.12.006; AGGARWAL N, 1979, ORG PREP PROCED INT, V11, P247; Becker RS, 1996, J PHYS CHEM-US, V100, P18683, DOI 10.1021-jp960852e; BEIMLING P, 1986, CHEM BER-RECL, V119, P3198, DOI 10.1002-cber.19861191025; Berlman I. B., 1971, HDB FLUORESCENCE SPE; BONNIER JM, 1970, J CHIM PHYS PCB, V67, P571; DAVYDOV SN, 1981, RUSS J PHYS CHEM, V55, P444; de Melo JS, 2003, J CHEM PHYS, V118, P1550, DOI 10.1063-1.1528604; de Melo JS, 2003, PHOTOCHEM PHOTOBIOL, V77, P121; Fichou D., 1999, HDB OLIGO POLYTHIOPH; FLICKER WM, 1976, J CHEM PHYS, V64, P1315, DOI 10.1063-1.432397; GENTILI PL, 2004, PHOTOCHEM PHOTOBIOL, V3, P881; Hadziioannou G, 2000, SEMICONDUCTING POLYM; Jabbarzadeh B, 1997, SPECTROSC LETT, V30, P1279, DOI 10.1080-00387019708006723; KIMURA O, 1988, Patent No. 63122727; Kunugi Y, 2004, J MATER CHEM, V14, P1367, DOI 10.1039-b401209g; Lap DV, 1997, J PHYS CHEM A, V101, P107, DOI 10.1021-jp961670n; Laquindanum JG, 1997, ADV MATER, V9, P36, DOI 10.1002-adma.19970090106; Luman CR, 2003, PHOTOCHEM PHOTOBIOL, V77, P510, DOI 10.1562-0031-8655(2003)0770510:LOFLIS2.0.CO;2; Meng H, 2005, J AM CHEM SOC, V127, P2406, DOI 10.1021-ja043189d; Merzlikine AG, 2004, PHOTOCH PHOTOBIO SCI, V3, P892, DOI 10.1039-b404580g; Murov S., 1993, HDB PHOTOCHEMISTRY; Nijegorodov N, 2001, SPECTROCHIM ACTA A, V57, P1449, DOI 10.1016-S1386-1425(00)00488-1; Pan HL, 2006, CHEM MATER, V18, P3237, DOI 10.1021-cm0602592; Perepichka IF, 2005, ADV MATER, V17, P2281, DOI 10.1002-adma.200500461; Perkampus H.-H, 1992, US VIS ATLAS ORGANIC; POMERANTZ M, 1994, MATER RES SOC SYMP P, V328, P227; Rentsch S, 1999, PHYS CHEM CHEM PHYS, V1, P1707, DOI 10.1039-a808617f; RYASHENTSEVA MA, 1988, IZV AKAD NAUK SSSR, V12, P2857; THYRION FC, 1973, J PHYS CHEM-US, V77, P1478, DOI 10.1021-j100631a002; TUROO N, 1991, MODERN MOL PHOTOCHEM; Wex B, 2006, J MATER CHEM, V16, P1121, DOI 10.1039-b512191d; Wex B, 2005, J ORG CHEM, V70, P4502, DOI 10.1021-jo048010w; Wex B, 2004, J ORG CHEM, V69, P2197, DOI 10.1021-jo035769j; WYNBERG H, 1970, J ORG CHEM, V35, P711, DOI 10.1021-jo00828a037; YOSHIDA S, 1994, J ORG CHEM, V59, P3077, DOI 10.1021-jo00090a027; ZANDER M, 1987, Z NATURFORSCH A, V42, P735; ZANDER M, 1985, Z NATURFORSCH A, V40, P497; ZANDER M, 1989, Z NATURFORSCH A, V44, P205119

    I stand alone where calm and clear the matin bells salute my ear [first line]

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    sectionalpiano and voiceJohns Hopkins University, Levy Sheet Music Collection, Box 122, Item 017Arranged for One Voice With a Piano Forte Accompaniment by Joseph Wex Herrmann.S. Ackerma

    I stand alone where calm and clear the matin bells salute my ear [first line]

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    sectionalpiano and voiceJohns Hopkins University, Levy Sheet Music Collection, Box 122, Item 017Arranged for One Voice With a Piano Forte Accompaniment by Joseph Wex Herrmann.S. Ackerma

    End-capping of conjugated thiophene-benzene aromatic systems

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    The synthesis of end-capped thieno[3,2-f:4,5-f′]bis[1]benzothiophene was achieved from thiophene and 2,5-thiophenedicarboxaldehyde. Specifically, hexyl and dodecyl end-capping groups conferred reversible redox behavior as evidenced by cyclic voltammetry with oxidation potentials of 0.73 V versus Fc-Fc+ couple. An extensive spectrophotometric analysis is reported. © 2010 Elsevier Ltd. All rights reserved.Barrash-Shiftan N, 1998, J PHYS ORG CHEM, V11, P743, DOI 10.1002-(SICI)1099-1395(1998100)11:10743::AID-POC393.0.CO;2-H; BAUERLE P, 1993, SYNTHESIS-STUTTGART, P1099, DOI 10.1055-s-1993-26009; Brusso JL, 2008, CHEM MATER, V20, P2484, DOI 10.1021-cm7030653; Coropceanu V, 2006, CHEM-EUR J, V12, P2073, DOI 10.1002-chem.200500879; Degheili JA, 2009, J PHYS CHEM A, V113, P1244, DOI 10.1021-jp8098363; Fichou D., 1999, HDB OLIGO POLYTHIOPH; Gao P, 2010, CHEM-EUR J, V16, P5119, DOI 10.1002-chem.200903562; Hains AW, 2010, ACS APPL MATER INTER, V2, P175, DOI 10.1021-am900634a; Helgesen M, 2010, MACROMOLECULES, V43, P1253, DOI 10.1021-ma9024812; Horowitz G, 2004, J MATER RES, V19, P1946, DOI 10.1557-JMR.2004.0266; Kagan C. R., 2003, THIN FILM TRANSISTOR; KALYANASUNDARAM K, 1977, J AM CHEM SOC, V99, P2039, DOI 10.1021-ja00449a004; Lakowicz J. R., 1999, PRINCIPLES FLUORESCE; LIPPERT E, 1957, Z ELEKTROCHEM, V61, P962; MATAGA N, 1956, B CHEM SOC JPN, V29, P465, DOI 10.1246-bcsj.29.465; Miyazaki E, 2009, J MATER CHEM, V19, P5913, DOI 10.1039-b910824f; MIYAZAKI E, 2008, Patent No. 2008108442; Moustafa RM, 2009, J PHYS CHEM A, V113, P1235, DOI 10.1021-jp809830x; Parker C.A., 1968, PHOTOLUMINESCENCE SO; Reichardt C., 1988, SOLVENTS SOLVENT EFF; REICHARDT C, 1994, CHEM REV, V94, P2319, DOI 10.1021-cr00032a005; SARAF SD, 1974, J MATH SCI, V1, P75; Shinamura S, 2010, J ORG CHEM, V75, P1228, DOI 10.1021-jo902545a; Shyamala T, 2006, CHEM PHYS, V330, P469, DOI 10.1016-j.chemphys.2006.09.018; Singh TB, 2006, ANNU REV MATER RES, V36, P199, DOI 10.1146-annurev.matsci.36.022805.094757; Subuddhi U, 2006, PHOTOCH PHOTOBIO SCI, V5, P459, DOI 10.1039-b600009f; Wex B, 2006, J MATER CHEM, V16, P1121, DOI 10.1039-b512191d; Wex B, 2006, J PHYS CHEM A, V110, P13754, DOI 10.1021-jp065548s; Wex B, 2005, J ORG CHEM, V70, P4502, DOI 10.1021-jo048010w; Wex B, 2004, J ORG CHEM, V69, P2197, DOI 10.1021-jo035769j; Xia CJ, 2002, ORG LETT, V4, P2067, DOI 10.1021-ol025943a0

    Gustav Ritter von Wex, sein Leben und Werk

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    Summary: The regulation works of Danube river along Vienna city around 1870 are described as a monumental European project of the 19th century. The publications of the project head Gustav von Wex (1811-1892) are thereby reviewed, given that he therein considered the historical bases, the imperial decision, the project outline and the advances of the works. In addition, the scientific works of von Wex are also described and put into a historical context. Finally, the biography of von Wex is presented along with the problems in searching successfully his portrait. This historical work is intended to add to the early developments in river engineering of Europ

    Efficacy of Wex-cide 128 disinfectant against multiple prion strains

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    Prion diseases are transmissible, fatal neurologic diseases that include Creutzfeldt-Jakob Disease (CJD) in humans, chronic wasting disease (CWD) in cervids, bovine spongiform encephalopathy (BSE) in cattle and scrapie in sheep. Prions are extremely difficult to inactivate and established methods to reduce prion infectivity are often dangerous, caustic, expensive, or impractical. Identifying viable and safe methods for treating prion contaminated materials is important for hospitals, research facilities, biologists, hunters, and meat-processors. For three decades, some prion researchers have used a phenolic product called Environ LpH (eLpH) to inactivate prions. ELpH has been discontinued, but a similar product, Wex-cide 128, containing the similar phenolic chemicals as eLpH is now available. In the current study, we directly compared the anti-prion efficacy of eLpH and Wex-cide 128 against prions from four different species (hamster 263K, cervid CWD, mouse 22L and human CJD). Decontamination was performed on either prion infected brain homogenates or prion contaminated steel wires and mouse bioassay was used to quantify the remaining prion infectivity. Our data show that both eLpH and Wex-cide 128 removed 4.0–5.5 logs of prion infectivity from 22L, CWD and 263K prion homogenates, but only about 1.25–1.50 logs of prion infectivity from human sporadic CJD. Wex-cide 128 is a viable substitute for inactivation of most prions from most species, but the resistance of CJD to phenolic inactivation is a concern and emphasizes the fact that inactivation methods should be confirmed for each target prion strain

    Brief: How WEX Stepped in to Offer Space to the Roux Institute

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    A brief look at how the space needs of the Roux Institute and WEX are being met, with Roux subletting space in WEX\u27s new Fore Street building in Portland. Both institutions face uncertainty due to the pandemic and needed short term solutions to their space needs

    WEX continues to eye expansion : a decade after IPO, technology is integral to global growth

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    WEX, the leading fleet card provider in the United States has achieved a 10% to 15% annual growth rate since it became publicly traded in 2005. WEX President and CEO Melissa Smith believes that growth rate can be sustained by accelerated growth, making targeted investments, and driving scale. The company has become more global and has acquisitioned travel, corporate and health payments to its business portfolio, will help the company achieve this growth. WEX has a customer base in nine European countries and physical offices in five countries. The company purchased Evolution1, a cloud-based technology and health care payment service, and Exxon Mobil’s European commercial fuel card program, which should give the company a solid opportunity to expand not only in Europe but in Asia Pacific market as well

    WEX a Step Closer to Securing Portland Site for HQ

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    WEX, a Maine business based in South Portland has submitted a bid to the Portland City Council to construct a new global headquarters in Portland for their business. The business will relocate some of their workers into new office space which will occupy part of the Thames Street building
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