15,135 research outputs found
Preliminary aerothermal design of axial compressors
No full textThis dissertation documents a compressor preliminary design study conducted by the author
in fulfilment of his MSc thesis requirements. The compressor is intended for a new
development engine within the 20Klbf thrust category, planned to be used on a short-haul
aircraft, namely the ERJ-190.
A market research suggests that there exists a definite opportunity for a commercially
profitable engine within this thrust class. Furthermore, the proposed new engine is projected
to outperform current production engines on critical issues such as fuel efficiency and
operability.
By and large, the objectives of this work have been achieved and a compressor design and
layout is suggested, which matched or exceeded all the initial requirements. The quality of
the results from this study are thought to be of sufficient detail to allow a further, more
detailed development study to resolve some subtle pending issues. It is expected that, some
compressor stages may have to be altered slightly during detailed design to augment their
performance and ease of manufacture and assembly.
Throughout this study, the importance of the compressor design figure of merits, pertaining
to a short haul engine, has been outlined and their interaction on the design process is well
documented. Furthermore, some rather unorthodox objectives such as compressor
performance retention and reliability have been discussed. The author approached these
subjects in an innovative way due to the limited non-proprietary knowledge available on
these issues, especially considering their implications within preliminary design.
Furthermore, the author developed and tested a new preliminary turbomachinery design code,
named Turbodev, which can be used as an aid in future compressor design endeveours.
Turbodev can handle most types of compressor layouts and generates an overall aerodynamic
assessment of the turbomachinery performance.
In conclusion; this documentation and the associated literature review aim to provide the
reader with an overview of the work done and yield a better understanding of the decisions
that face any design bureau when developing a new or modified engine component.The research work disclosed in this publication is partially funded by the
Strategic Educational Pathways Scholarship Scheme (Malta). The
scholarship is part-financed by the European Union – European Social
Fund under Programme II – Cohesion Policy 2007-2013
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No full textXML wordt in veel situaties gebruikt, en voor dat gebruik worden talloze tools gebouwd. Er zijn verschillende manieren om XML-tools te ontwikkelen, en dit artikel behandelt de voor- en nadelen van de verschillende alternatieven. XML en XML-tools De uitgever Kluwer biedt verschillende soorten informatie aan, zoals wetteksten en belastinggidsen. Deze informatie heeft vaak een vaste structuur: een wet heeft bijvoorbeeld altijd een nummer, en een belastinggids beschrijft componenten die voorkomen op het inkomstenbelastingformulier. De structuur verschilt echter van informatiesoort tot informatiesoort. Voor de beschrijving van een document van dit soort structuren gebruikt Kluwer de Extensible Markup Language (XML) [6], en voor de beschrijving van een structuur zelf een Document Type Definitions (DTD) of een Schema. Een manier om de populariteit van een onderwerp te bepalen is Google te vragen hoe vaak een term voorkomt op het Web, of eigenlijk, in de databases van Google. Zo komen de Beatles bijna 3 miljoen keer voor, en ABBA honderdduizend keer. XML komt ongeveer 20 miljoen keer voor, en verslaat daarmee alle programmeertalen behalve Java. Een andere populariteitsmaat is het aantal vierkante meters boekenplank dat in beslag wordt genomen door boeken over het onderwerp in een academische boekhandel. In mijn lokale boekhandel verslaat XML menig andere nieuwe technologie. Maar wat is XML? XML is een eenvoudig, flexibel tekstformaat, dat veel gebruikt wordt voor het uitwisselen van data op het internet, maar ook tussen bedrijven onderling, en tussen bedrijven en hun klanten. Hier is een voorbeeld van een XML document
Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation
No full textAmyloid formation is cytotoxic and can activate the caspase cascade. Here, we monitor caspase-3-like activity as reduction of fluorescence resonance energy transfer (FRET) using the contstruct pFRET2-DEVD containing enhanced cyan fluorescent protin (EYFP) linked by the caspase-3 specific cleavage site residues DEVD. Beta-TC-6 cells were transfected, and the fluoorescence was measured at 440 nm excitation and 535 nm (EYFP) and 480 nm (ECFP) emission wavelength. Cells were incubated with recombinant pro lset Amyloid Polypeptide (rec prolAPP) or the processing metabolites of prolAPP; the N-terminal flanking peptide withIAPP (recN+IAPP); IAPP with the C-terminal flanking peptied (recIAPP+C) and lslet Amyloid Polypeptide (recIAPP). Peptides were added in solubilized from (50 mu M) or as performed amyloid-like fibrils, or as a combination of these. FRET was measured and incubation with a mixture of solubilized peptide and performed fibrils resulted in loss of FRET and apoptosis was determined to occurein cells incubated with recproIAPP (49%), recN+IAPP (46%), recIAPP (72%) and recIAPP+C (59%). These results show that proIAPP and the processing intermediates reside the same cell toxic capacity as IAPP, and they can all have a central role in the reduction of beta-cell number in type 2 diabetes.Original Publication:Johan F Paulsson, Sebastian Schultz, Martin Kohler, Ingo Leibiger, Per-Olof Berggren and Gunilla Westermark, Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation, 2008, EXPERIMENTAL DIABETES RESEARCH, (2008), 865850.http://dx.doi.org/10.1155/2008/865850Copyright: Author
A comparison of amyloid deposition in human and transgenic mouse islets of Langerhans transplanted into nude mice
No full textClueS Collusive Stealing Framework
No full text<p>Please check the code here for now (anonymous git repository): </p><p>https://anonymous.4open.science/r/federated-stealing-D782/README.md</p>
Fabrication of Nanoslits with <111> Etching TSWE Method
No full textIn this paper, we report a modified three step anisotropic wet etching (TSWE) method to fabricate solid-state silicon nanoslits. The slit-opening process is performed by <111> crystal plane etching. The etching rate of the <111> crystal plane is reasonably slow as it is only 1/45 of the <100> etching rate, thus allowing and therefore good slits-opening controllability. By slowly etching the <111> crystal plane, the over-etching was effectively reduced. Perfectly rectangular nanoslits with different dimensions were successfully obtained. The smallest achieved feature size of the nanoslit is 8.3 nm.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Components, Technology and Material
A Conversation about Aliens, AIs and Jack Benny
No full textPresented on March 14, 2019 at 11:00 a.m. in the Crosland Tower, 7th floor reading room.Jack McDevitt is a former English teacher, naval officer, Philadelphia taxi driver, customs officer and motivational trainer. His work has been on the final ballot for the Nebula Awards for 12 of the past 13 years, and he holds 16 nominations in total. His first novel, The Hercules Text, was published in the celebrated Ace Specials series and won the Philip K. Dick Special Award. In 1991, McDevitt won the first $10,000 UPC International Prize for his novella, "Ships in the Night." The Engines of God was a finalist for the Arthur C. Clarke Award, and his novella, "Time Travelers Never Die," was nominated for both the Hugo and the Nebula awards.Runtime: 60:59 minutesThe Georgia Tech Library is proud to host Nebula Award-winning author Jack McDevitt in the Seventh Floor Reading Room Thursday, March 14 for “A Conversation about Aliens, AIs and Jack Benny with Sci-Fi Author Jack McDevitt
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