2,570 research outputs found
Oral History Interview with Rueben C. Warren
No full textThis interview with Rueben Warren, DDS, DrPH, is part of “Moral Histories: Voices and Stories from the Founding Figures of Bioethics,” an oral history project of the Johns Hopkins Berman Institute of Bioethics. Dr. Warren is Dean Emeritus, School of Dentistry, Meharry Medical College and former Director of the National Center for Bioethics and Professor Emeritus of Bioethics at Tuskegee University. He also spent many years working at the Department of Health and Human Services and the Centers for Disease Control. His expertise includes dental health, access to oral healthcare, public health, faith communities, and environmental justice. He is the author of over one hundred journal articles.
Dr. Warren discussed the close-knit community of his childhood in the Watts neighborhood of South Central Los Angeles and his higher education experiences at San Francisco State University, Meharry Medical College, Harvard University, and the Interdenominational Theological Center. He described being on the Tuskegee Syphilis Study Legacy Committee, the 1997 apology from President Bill Clinton, and the subsequent establishment of the National Center for Bioethics in Research and Healthcare at Tuskegee University. While director, he shared how he focused on engaging descendants of the U.S. Public Health Service Syphilis Study, established programming with Black church leaders, and developed a bioethics honors program. He described the need for institutions to prove their trustworthiness to gain community trust, particularly in healthcare settings.
He discussed working in the Office of Minority Health and the Agency for Toxic Substances and Disease Registry, where he investigated environmental harms and the disproportionate impact on low-income and minority communities. The Covid-19 pandemic occurred during his last years at Tuskegee and he shares that experience as why medical providers and bioethicists should examine the trustworthiness of institutions versus implicating vaccine-hesitant communities. The conversation ends with a comparison of the Human Genome Project to the work of the Diaspora Human Genomic Institute, emphasizing the importance of involving Black scientists and communities in data collection, preservation, and analysis
Liberty\u27s Last Post Office: A Story of a Gold MIning Camp in Washington State
No full textThere was once a large center of activity in the Swauk Basin of upper Kittitas County. The place is called Liberty. Liberty was once the most action packed place in Kittitas County. At least it was for a while after gold was discovered in Swauk Creek. Like many gold camps the place boomed and ebbed over the years. Unlike some other places it never quite went completely bust. It came close, and fortunately for some it didn’t. It still exists today as a living ghost town.
The Liberty story has been told before in various ways. This telling of the story revolves around the end of Liberty’s role as an active mining community and its close call with complete destruction. It is about four Nicholson brothers and their store, the last post office in Liberty, and the people who later saved the mining camp as a historic site to show the next generation what came before.
My thanks to Fred Krueger for preserving Liberty history in the form of oral interviews of old time miners and for his encouragement to write history in my own way. That is, to simply preserve history, not to rewrite it. Thanks also to Pattie Nicholson, Robert Nicholson’s wife, and Warren Leyde, Freida Nicholson’s nephew, for graciously sharing family documents and pictures that made this story possible.https://digitalcommons.cwu.edu/local_authors/1002/thumbnail.jp
sj-docx-2-jor-10.1177_20551169221137536 – Supplemental material for CTSK variant implicated in suspected pyknodysostosis in a domestic cat
No full textSupplemental material, sj-docx-2-jor-10.1177_20551169221137536 for CTSK variant implicated in suspected pyknodysostosis in a domestic cat by Maria Lyraki, Angie Hibbert, Sorrel Langley-Hobbs, Philippa Lait, Reuben M Buckley, Wesley C Warren, Leslie A Lyons and 99 Lives Consortium in Journal of Feline Medicine and Surgery Open Reports</p
The enigma of the platypus genome
No full text© CSIRO 2009Over two centuries after the first platypus specimen stirred the scientific community in Europe, the whole-genome sequence of the duck-billed platypus has been completed and is publicly available. After publication of eutherian and marsupial genomes, this is the first genome of a monotreme filling an important evolutionary gap between the divergence of birds more that 300 million years ago and marsupials more than 140 million years ago. Monotremes represent the most basal surviving branch of mammals and the platypus genome sequence allows unprecedented insights into the evolution of mammals and the fascinating biology of the egg-laying mammals. Here, we discuss some of the key findings of the analysis of the platypus genome and point to new findings and future research directions, which illustrate the broad impact of the platypus genome project for understanding monotreme biology and mammalian genome evolution.Wesley C. Warren and Frank Grützne
sj-xlsx-3-jor-10.1177_20551169221137536 – Supplemental material for CTSK variant implicated in suspected pyknodysostosis in a domestic cat
No full textSupplemental material, sj-xlsx-3-jor-10.1177_20551169221137536 for CTSK variant implicated in suspected pyknodysostosis in a domestic cat by Maria Lyraki, Angie Hibbert, Sorrel Langley-Hobbs, Philippa Lait, Reuben M Buckley, Wesley C Warren, Leslie A Lyons and 99 Lives Consortium in Journal of Feline Medicine and Surgery Open Reports</p
sj-docx-1-jor-10.1177_20551169221137536 – Supplemental material for CTSK variant implicated in suspected pyknodysostosis in a domestic cat
No full textSupplemental material, sj-docx-1-jor-10.1177_20551169221137536 for CTSK variant implicated in suspected pyknodysostosis in a domestic cat by Maria Lyraki, Angie Hibbert, Sorrel Langley-Hobbs, Philippa Lait, Reuben M Buckley, Wesley C Warren, Leslie A Lyons and 99 Lives Consortium in Journal of Feline Medicine and Surgery Open Reports</p
Genome analysis of the platypus reveals unique signatures of evolution
No full textWe present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology. Expansions of protein, non-protein-coding RNA and microRNA families, as well as repeat elements, are identified. Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation.This article is published as Warren, Wesley C., LaDeana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov et al. "Genome analysis of the platypus reveals unique signatures of evolution." Nature 453, no. 7192 (2008): 175. doi: 10.1038/nature06936.</p
The warren court and the black community, 1980
No full textU.S. Supreme Court decisions involving the black community were studied for the 1953-1969 terms, the Warren Court ear. The hypothesis of the study was that after 1962 when the Court achieved a liberal majority the decisions would be more favorable to the black community than was true before 1962. This hypothesis was tested by the use of an eight point scale evaluation of each c-f the. sixty-eight cases studied. The hypothesis was proved correct. The Warren Court was more favorable to the black community during its liberal period than during its conservative period
A Personal Remembrance of Warren Bennis
No full textIn January 2010, I fulfilled a decades-long dream of driving Route 66 from Chicago to the Santa Monica Pier and back. On Jan. 21, 2010 I celebrated making it to the Pacific Ocean by 41 I visiting with a dear friend, the noted leadership author Warren Bennis, who lived in Santa Monic
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