1,436 research outputs found

    Dr. Shanesha R.F. Brooks-Tatum, RWWL AUC, July 2011

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    This video is a conversation with Dr. Shanesha R.F. Brooks-Tatum. Dr. Brooks-Tatum talks about her book, "The Encyclopedia of Hip Hop Literature." Daniel Le, AUC Woodruff Library, is the interviewer

    Letter: R.F. Pettigrew to H.L. Loucks, May 30, 1916

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    R.F. Pettigrew articulates to H.L. Loucks his distaste for the book that Loucks recommended to him. Pettigrew also mentions that he would prefer to remain distanced from any conference with the author of the book. Pettigrew expresses great admiration and interest in Loucks' manuscript and desire to read it further

    The evolution of fat grafting : from soft tissue augmentation to regenerative medicine

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    The Author traces the evolution of fat grafting over the years from the first publication in 1893, to the systematization of the technique thanks to the contribution of Sydney Coleman. In recent years studies on the nature of adipose tissue have shown that besides multiple resident cells, fat tissue contains stem cells (ADSCs) capable of differentiating in multiple lineages, such as bone, cartilage, muscle, nerve, etc. Thus, in addition to the traditional notion that fat is a high energy reservoir, it becomes apparent that fat is a repair organ providing the basis for soft tissue regeneration. Manipulation of ADSCs promises to affect different fields of medicine and provide the physician with a variety of regenerative medical therapies

    Low-frequency model-order reduction of electromagnetic fields without matrix factorization

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    Electrical Engineering, Mathematics and Computer Scienc

    Effects Of Sterilization Methods On The Physical, Chemical, And Biological Properties Of Silk Fibroin Membranes

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    Silk fibroin has been widely explored for many biomedical applications, due to its biocompatibility and biodegradability. Sterilization is a fundamental step in biomaterials processing and it must not jeopardize the functionality of medical devices. The aim of this study was to analyze the influence of different sterilization methods in the physical, chemical, and biological characteristics of dense and porous silk fibroin membranes. Silk fibroin membranes were treated by several procedures: immersion in 70% ethanol solution, ultraviolet radiation, autoclave, ethylene oxide, and gamma radiation, and were analyzed by scanning electron microscopy, Fourier-transformed infrared spectroscopy (FTIR), X-ray diffraction, tensile strength and in vitro cytotoxicity to Chinese hamster ovary cells. The results indicated that the sterilization methods did not cause perceivable morphological changes in the membranes and the membranes were not toxic to cells. The sterilization methods that used organic solvent or an increased humidity and/or temperature (70% ethanol, autoclave, and ethylene oxide) increased the silk II content in the membranes: the dense membranes became more brittle, while the porous membranes showed increased strength at break. Membranes that underwent sterilization by UV and gamma radiation presented properties similar to the nonsterilized membranes, mainly for tensile strength and FTIR results. © 2013 Wiley Periodicals, Inc.1024869876Vepari, C., Kaplan, D.L., Silk as a biomaterial (2007) Progress in Polymer Science (Oxford), 32 (8-9), pp. 991-1007. , DOI 10.1016/j.progpolymsci.2007.05.013, PII S0079670007000731, Polymers in Biomedical ApplicationsHakimi, O., Knight, D.P., Vollrath, F., Vadgama, P., Spider and mulberry silkworm silks as compatible biomaterials (2007) Composites Part B: Engineering, 38 (3), pp. 324-337. , DOI 10.1016/j.compositesb.2006.06.012, PII S1359836806001284Jin, H.-J., Kaplan, D.L., Mechanism of silk processing in insects and spiders (2003) Nature, 424 (6952), pp. 1057-1061. , DOI 10.1038/nature01809Nogueira, G.M., Rodas, A.C.D., Leite, C.A.P., Giles, C., Higa, O.Z., Polakiewicz, B., Beppu, M.M., Preparation and characterization of ethanol-treated silk fibroin dense membranes for biomaterials application using waste silk fibers as raw material (2010) Bioresour Technol, 101, pp. 8446-8451Altman, G.H., Diaz, F., Jakuba, C., Calabro, T., Horan, R.L., Chen, J., Lu, H., Kaplan, D.L., Silk-based biomaterials (2003) Biomaterials, 24 (3), pp. 401-416. , DOI 10.1016/S0142-9612(02)00353-8, PII S0142961202003538Um, I.C., Kweon, H., Park, Y.H., Hudson, S., Structural characteristics and properties of the regenerated silk fibroin prepared from formic acid (2001) International Journal of Biological Macromolecules, 29 (2), pp. 91-97. , DOI 10.1016/S0141-8130(01)00159-3, PII S0141813001001593Macintosh, A.C., Kearns, V.R., Crawford, A., Hatton, P.V., Skeletal tissue engineering using silk biomaterials (2008) J Tissue Eng Regen Med, 2, pp. 71-80Lee, K.H., Ki, C.S., Back, D.H., Kang, G.D., Ihm, D.-W., Park, Y.H., Application of electrospun silk fibroin nanofibers as an immobilization support of enzyme (2005) Fibers and Polymers, 6 (3), pp. 181-185Vangsness Jr., C.T., Wagner, P.P., Moore, T.M., Roberts, M.R., Overview of Safety Issues Concerning the Preparation and Processing of Soft-Tissue Allografts (2006) Arthroscopy - Journal of Arthroscopic and Related Surgery, 22 (12), pp. 1351-1358. , DOI 10.1016/j.arthro.2006.10.009, PII S0749806306013144Fuchs, S., Motta, A., Migliaresi, C., Kirkpatrick, C.J., Outgrowth endothelial cells isolated and expanded from human peripheral blood progenitor cells as a potential source of autologous cells for endothelialization of silk fibroin biomaterials (2006) Biomaterials, 27 (31), pp. 5399-5408. , DOI 10.1016/j.biomaterials.2006.06.015, PII S0142961206005722Gotoh, Y., Tsukada, M., Minoura, N., Imai, Y., Synthesis of poly(ethylene glycol)-silk fibroin conjugates and surface interaction between L-929 cells and the conjugates (1997) Biomaterials, 18 (3), pp. 267-271. , DOI 10.1016/S0142-9612(96)00137-8, PII S0142961296001378Yang, Y., Chen, X., Ding, F., Zhang, P., Liu, J., Gu, X., Biocompatibility evaluation of silk fibroin with peripheral nerve tissues and cells in vitro (2007) Biomaterials, 28 (9), pp. 1643-1652. , DOI 10.1016/j.biomaterials.2006.12.004, PII S0142961206010192Panilaitis, B., Altman, G.H., Chen, J., Jin, H.-J., Karageorgiou, V., Kaplan, D.L., Macrophage responses to silk (2003) Biomaterials, 24 (18), pp. 3079-3085. , DOI 10.1016/S0142-9612(03)00158-3Fini, M., Motta, A., Torricelli, P., Giavaresi, G., Nicoli Aldini, N., Tschon, M., Giardino, R., Migliaresi, C., The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel (2005) Biomaterials, 26 (17), pp. 3527-3536. , DOI 10.1016/j.biomaterials.2004.09.040, PII S0142961204008695Marreco, P.R., Da Luz Moreira, P., Genari, S.C., Moraes, A.M., Effects of different sterilization methods on the morphology, mechanical properties, and cytotoxicity of chitosan membranes used as wound dressings (2004) Journal of Biomedical Materials Research - Part B Applied Biomaterials, 71 (2), pp. 268-277. , DOI 10.1002/jbm.b.30081Siritientong, T., Srichana, T., Aramwit, P., The effect of sterilization methods on the physical properties of silk sericin scaffolds (2011) Aaps Pharmscitech, 12, pp. 771-781Von Woedtke, T., Julich, W.-D., Hartmann, V., Stieber, M., Abel, P.U., Sterilization of enzyme glucose sensors: Problems and concepts (2002) Biosensors and Bioelectronics, 17 (5), pp. 373-382. , DOI 10.1016/S0956-5663(01)00310-4, PII S0956566301003104Lee, M.H., Kim, H.-L., Kim, C.H., Lee, S.H., Kim, J.K., Lee, S.J., Park, J.-C., Effects of low temperature hydrogen peroxide gas on sterilization and cytocompatibility of porous poly(d,l -lactic-co-glycolic acid) scaffolds (2008) Surf Coat Technol, 202, pp. 5762-5767Block, S.S., (2001) Disinfection, Sterilization, and Preservation, , Baltimore: Lippincott Williams & WilkinsPalsule, A.S., Clarson, S.J., Widenhouse, C.W., Gamma irradiation of silicones (2008) J Inorg Organomet Polym Mater, 18, pp. 207-221BR200601975-A, Unicamp Univ Estadual Campinas, invs.: M. M. Beppu, B. Polakiewicz, G. M. Nogueira2008Lv, Q., Cao, C., Zhang, Y., Ma, X.L., Zhu, H., Preparation of insoluble fibroin films without methanol treatment (2005) Journal of Applied Polymer Science, 96 (6), pp. 2168-2173. , DOI 10.1002/app.21682Miyaguchi, Y., Hu, J., Physicochemical properties of silk fibroin after solubilization using calcium chloride with or without ethanol (2005) Food Science and Technology Research, 11 (1), pp. 37-42Rusa, C.C., Bridges, C., Ha, S.-W., Tonelli, A.E., Conformational changes induced in Bombyx mori silk fibroin by cyclodextrin inclusion complexation (2005) Macromolecules, 38 (13), pp. 5640-5646. , DOI 10.1021/ma050340aUm, I.C., Ki, C.S., Kweon, H., Lee, K.G., Ihm, D.W., Park, Y.H., Wet spinning of silk polymer: II. Effect of drawing on the structural characteristics and properties of filament (2004) International Journal of Biological Macromolecules, 34 (1-2), pp. 107-119. , DOI 10.1016/j.ijbiomac.2004.03.011, PII S0141813004000145Zuo, B., Liu, L., Wu, Z., Effect on properties of regenerated silk fibroin fiber coagulated with aqueous methanol/ethanol (2007) Journal of Applied Polymer Science, 106 (1), pp. 53-59. , DOI 10.1002/app.26653Lawrence, B.D., Omenetto, F., Chui, K., Kaplan, D.L., Processing methods to control silk fibroin film biomaterial features (2008) J Mater Sci, 43, pp. 6967-6985Tamada, Y., New process to form a silk fibroin porous 3-D structure (2005) Biomacromolecules, 6 (6), pp. 3100-3106. , DOI 10.1021/bm050431fMoonsri, P., Watanesk, R., Watanesk, S., Niamsup, H., Deming, R.L., Fibroin membrane preparation and stabilization by polyethylene glycol diglycidyl ether (2008) Journal of Applied Polymer Science, 108 (3), pp. 1402-1406. , DOI 10.1002/app.27528Li, M., Lu, S., Wu, Z., Tan, K., Minoura, N., Kuga, S., Structure and properties of silk fibroin-poly(vinyl alcohol) gel (2002) International Journal of Biological Macromolecules, 30 (2), pp. 89-94. , DOI 10.1016/S0141-8130(02)00007-7, PII S0141813002000077Kim, S.H., Nam, Y.S., Lee, T.S., Park, W.H., Silk fibroin nanofiber. Electrospinning, properties, and structure (2003) Polym J, 35, pp. 185-190Lv, Q., Cao, C., Zhang, Y., Man, X., Zhu, H., The preparation of insoluble fibroin films induced by degummed fibroin or fibroin microspheres (2004) Journal of Materials Science: Materials in Medicine, 15 (11), pp. 1193-1197. , DOI 10.1007/s10856-004-5918-yPutthanarat, S., Zarkoob, S., Magoshi, J., Chen, J.A., Eby, R.K., Stone, M., Adams, W.W., Effect of processing temperature on the morphology of silk membranes (2002) Polymer, 43 (12), pp. 3405-3413. , DOI 10.1016/S0032-3861(02)00161-1, PII S0032386102001611Nogueira, G.M., Rodas, A.C.D., Weska, R.F., Aimoli, C.G., Higa, O.Z., Maizato, M., Leiner, A.A., Beppu, M.M., Bovine pericardium coated with biopolymeric films as an alternative to prevent calcification: In vitro calcification and cytotoxicity results (2010) Mater Sci Eng C Mater Biol Appl, 30, pp. 575-582Wang, X., Kim, H.J., Xu, P., Matsumoto, A., Kaplan, D.L., Biomaterial coatings by stepwise deposition of silk fibroin (2005) Langmuir, 21 (24), pp. 11335-11341. , DOI 10.1021/la051862mNogueira, G.M., Weska, R.F., Vieira, W.C., Polakiewicz, B., Rodas, A.C.D., Higa, O.Z., Beppu, M.M., A new method to prepare porous silk fibroin membranes suitable for tissue scaffolding applications (2009) J Appl Polym Sci, 114, pp. 617-623Weska, R.F., Nogueira, G.M., Vieira, Jr.W.C., Beppu, M.M., Porous silk fibroin membrane as a potential scaffold for bone regeneration (2009) Key Eng Mater, 396-398, pp. 187-19

    In memory of Paul Tessier, MD (1917-2008)

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    The Author traces the life and the surgical achievements of Paul Tessier, founder of craniofacial surgery

    Old and new in fat grafting

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    The author traces the evolution of fat grafting over the years and shows the potential clinical applications in the different areas of the body

    Presentazione

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    The Author traces the evolution of Aesthetic Rhinoplasty in Italy from the first contribution published by G. Sanvenero Rosselli in 1931

    Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution

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    Non-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit

    Nuclear paramagnetic relaxation with off-resonant r.f. fields

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    The behaviour of a paramagnetic spin system irradiated by a radio-frequency field far from resonance is studied in the frame of the theory already developed by the author. The time evolution and the equilibrium characteristics are calculated in the case of the Einbinder-Hartmann and Lee-Goldburg experiments. Theoretical and experimental results agree and the behaviour of the system may be interpreted in the case where the nonresonant character of the r.f. field modifies the usual characteristics of the evolution. © 1973.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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