1,721,599 research outputs found
DIALIGN: finding local similarities by multiple sequence alignment
No full textMorgenstern B, Frech K, Dress A, Werner T. DIALIGN: finding local similarities by multiple sequence alignment. Bioinformatics. 1998;14(3):290-294.Motivation: DIALIGN is a new method for pairwise as Well as multiple alignment oSlzucleic acid and protein sequences. While standard alignment programs rely on comparing single residues and imposing gap penalties, DIALIGN constructs alignments by comparing whole segments of the sequences. No gap penalty is employed. This point of view is especially adequate if sequences ai-e not globally related, bur share only local similarities, as is the case in genomic DNA sequences and in many protein families. Results: Using four different data sers, we show that DIALICN is able correctly to align conserved motifs in protein sequences. Alignments produced by DIALIGN are compared systematically to the results of five other alignment programs
Zuwanderung nach Österreich
Full text linkZUWANDERUNG NACH ÖSTERREICH
Zuwanderung nach Österreich / Bauer, Werner T. (Rights reserved) (-
Willkommen in der Normalität? : Anmerkungen zum Wahlerfolg der rechten Schwedendemokraten
No full textWerner T. BauerElectronic ed.: Berlin ; Bonn : FES, 2010. - Title only available onlin
Rechtspopulismus in Europa
No full textWerner T. BauerElectronic ed.: Paris ; Bonn : FES, 2011. - Title only available onlin
Multiple DNA and protein sequence alignment based on segment-to-segment comparison
No full textMorgenstern B, Dress A, Werner T. Multiple DNA and protein sequence alignment based on segment-to-segment comparison. Proceedings of the National Academy of Sciences of the United States. 1996;93(22):12098-12103.In this paper, a new way to think about, and to construct, pairwise as well as multiple alignments of DNA and protein sequences is proposed. Rather than forcing alignments to either align single residues or to introduce gaps by defining an alignment as a path running right from the source up to the sink in the associated dot-matrix diagram, we propose to consider alignments as consistent equivalence relations defined on the set of all positions occurring in all sequences under consideration. We also propose constructing alignments from whole segments exhibiting highly significant overall similarity rather than by aligning individual residues, Consequently, we present an alignment algorithm that (i) is based on segment-to-segment comparison instead of the commonly used residue-to-residue comparison and which (ii) avoids the well-known difficulties concerning the choice of appropriate gap penalties: gaps are not treated explicitly, but remain as those parts of the sequences that do not belong to any of the aligned segments. Finally, we discuss the application of our algorithm to two test examples and compare it with commonly used alignment methods. As a first example, we aligned a set of 11 DNA sequences coding for functional helix-loop-helix proteins. Though the sequences show only low overall similarity, our program correctly aligned all of the 11 functional sites, which was a unique result among the methods tested, As a by-product, the reading frames of the sequences were identified. Next, we aligned a set of ribonuclease EI proteins and compared our results with alignments produced by other programs as reported by McClure et al. [McClure, M. A., Vasi, T. K. & Fitch, W. M. (1994) Mol. Biol. Evol. 11, 571-592]. Our program was one of the best scoring programs. However, in contrast to other methods, our protein alignments are independent of user-defined parameters
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Angress (Werner T.). Stillborn Revolution. The Communist Bid for Power in Germany, 1921-1923
No full textKriegel Annie. Angress (Werner T.). Stillborn Revolution. The Communist Bid for Power in Germany, 1921-1923. In: Revue belge de philologie et d'histoire, tome 43, fasc. 3, 1965. Langues et littératures modernes - Moderne taal- en letterkunde. pp. 1105-1110
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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