196,985 research outputs found
Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development
No full textThis project provides code and data to reproduce the results, figures, and supplementary material of the paper: Joechner, A. K., Hahn, M. A., Gruber, G., Hoedlmoser, K., & Werkle-Bergner, M. (2023). Sleep spindle maturity promotes slow oscillation-spindle coupling
across child and adolescent development. eLIFE DOI: https://doi.org/10.7554/eLife.8356
Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development
No full textThis project provides code and data to reproduce the results, figures, and supplementary material of the paper: Joechner, A. K., Hahn, M. A., Gruber, G., Hoedlmoser, K., & Werkle-Bergner, M. (2023). Sleep spindle maturity promotes slow oscillation-spindle coupling
across child and adolescent development. eLIFE DOI: https://doi.org/10.7554/eLife.8356
Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development
No full textThis project provides code and data to reproduce the results, figures, and supplementary material of the paper: Joechner, A. K., Hahn, M. A., Gruber, G., Hoedlmoser, K., & Werkle-Bergner, M. (2023). Sleep spindle maturity promotes slow oscillation-spindle coupling
across child and adolescent development. eLIFE DOI: https://doi.org/10.7554/eLife.8356
Disputationem inauguralem de dysenteria
No full text... pro doctoratus in medicina insigniis & privilegiis rite consequendis publicae ... ventilationi proponit M. Georgius Bergner Coburgo-Francus ad diem 4. Iulii, anno M D CXXII. ...Druckjahr nach Datum auf dem TitelblattDatum auf Titelblatt hs. geändert: ad diem 6. Iulii, anno M D CXXIIEnth. 34 ThesenDiss. med. Basel, 162
Lower MR-indexed locus coeruleus integrity in autosomal-dominant Alzheimer’s disease is related to cortical tau burden and memory deficits
No full textAuthors:
Martin J. Dahl* 1,2, Mara Mather 2, Markus Werkle-Bergner 1, Briana L. Kennedy 2,3, Samuel Guzman 4, Kyle Hurth4, Carol A. Miller 4, Yuchuan Qiao 5, Yonggang Shi5, Helena C. Chui 6, & John M. Ringman 6
Affiliations:
1 Center for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany
2 Davis School of Gerontology, University of Southern California, 90089 Los Angeles, CA, USA
3 School of Psychological Science, University of Western Australia, Perth, Australia
4 Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
5 Laboratory of Neuro Imaging (LONI), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
6 Department of Neurology, Keck School of Medicine, University of Southern California, 90033 Los Angeles, CA, USA
* Corresponding author:
MJD (dahl [at] mpib-berlin.mpg.de)
We aimed at improving the reliability and validity of MR-based locus coeruleus detection. Leveraging a meta-analytical approach, we aggregated across previously published maps of the locus coeruleus (Betts et al., 2017; Dahl et al., 2019; Keren et al., 2009; Liu et al., 2019; Tona et al., 2017; Ye et al., 2020) to derive a biologically plausible volume of interest (meta mask) that shows high agreement across investigations. We freely share the locus coeruleus meta mask with the scientific community.
For a description of the methods, please see:
https://doi.org/10.1101/2020.11.16.2023256
Age differences in oscillatory SME
No full textAnalysis Scripts and Data related to the following article:
Sander, M. C., Fandakova, Y., Grandy, T. H., Shing, Y. L., & Werkle-Bergner, M. (2020). Oscillatory mechanisms of successful memory formation in younger and older adults are related to structural integrity. Cerebral Cortex. Advance online publication. https://doi.org/10.1093/cercor/bhz339
Preprint version:
Sander, M. C., Fandakova, Y., Grandy, T. H., Shing, Y. L., & Werkle-Bergner, M. (2019). Oscillatory mechanisms of successful memory formation in younger and older adults are related to structural integrity. BioRxiv, 530121. doi:10.1101/53012
Age differences in oscillatory SME
No full textAnalysis Scripts and Data related to the following article:
Sander, M. C., Fandakova, Y., Grandy, T. H., Shing, Y. L., & Werkle-Bergner, M. (2020). Oscillatory mechanisms of successful memory formation in younger and older adults are related to structural integrity. Cerebral Cortex. Advance online publication. https://doi.org/10.1093/cercor/bhz339
Preprint version:
Sander, M. C., Fandakova, Y., Grandy, T. H., Shing, Y. L., & Werkle-Bergner, M. (2019). Oscillatory mechanisms of successful memory formation in younger and older adults are related to structural integrity. BioRxiv, 530121. doi:10.1101/53012
Associative and Strategic Components of Episodic Memory: A Life-Span Dissociation
Get PDFThe authors investigated the strategic component (i.e., elaboration and organization of episodic features) and the associative component (i.e., binding processes) of episodic memory and their interactions in 4 age groups (10-12, 13-15, 20-25, and 70-75 years of age). On the basis of behavioral and neural evidence, the authors hypothesized that the two components are functionally related but follow different life-span gradients. In a fully crossed design, age differences in recognition memory for single words versus word pairs (associative demand manipulation) were examined under instructions that emphasized item, pair, or elaborative-pair encoding (strategy manipulation). As predicted, the results showed that the strategic and associative components follow different life-span trajectories. Relative to younger adults, children's difficulties in episodic memory primarily reflected lower levels of strategic functioning. In contrast, older adults showed impairments in both strategic and associative components. The authors conclude that the comparison of strategic and associative components of episodic memory across the life span helps to delineate the two components' unique and interactive contributions to episodic memory performance
Committing memory errors with high confidence: Older adults do but children don't
Get PDFWe investigated lifespan differences of confidence calibration in episodic memory, particularly the susceptibility to high-confidence errors within samples of children, teenagers, younger adults, and older adults. Using an associative recognition memory paradigm, we drew a direct link between older adults' associative deficit and high-confidence errors. We predicted that only older adults would show high-confidence error even though their memory performance was at a similar level to that of children. Participants of all ages showed higher confidence following correct responses compared to incorrect responses, demonstrating the ability to calibrate subjective confidence in relation to memory accuracy. However, older adults were disproportionately more likely to indicate high confidence following erroneously remembered word pairs than participants of the other three age groups. Results are discussed in relation to the misrecollection account of high-confidence errors and ageing-related decline in hippocampus-dependent episodic memory functions
The Influence of Prior Knowledge on Memory: A Developmental Cognitive Neuroscience Perspective
Get PDFAcross ontogenetic development, individuals gather manifold experiences during which they detect regularities in their environment and thereby accumulate knowledge. This knowledge is used to guide behavior, make predictions, and acquire further new knowledge. In this review, we discuss the influence of prior knowledge on memory from both the psychology and the emerging cognitive neuroscience literature and provide a developmental perspective on this topic. Recent neuroscience findings point to a prominent role of the medial prefrontal cortex (mPFC) and of the hippocampus in the emergence of prior knowledge and in its application during the processes of successful memory encoding, consolidation, and retrieval. We take the lateral PFC into consideration as well and discuss changes in both medial and lateral PFC and hippocampus across development and postulate how these may be related to the development of the use of prior knowledge for remembering. For future direction, we argue that, to measure age differential effects of prior knowledge on memory, it is necessary to distinguish the availability of prior knowledge from its accessibility and use
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