102,466 research outputs found
Adjusted winner
Get PDFRaith MG, Welzel A. Adjusted winner. Working Papers. Institute of Mathematical Economics. Vol 295. Bielefeld: Center for Mathematical Economics; 1998
In vivo imaging of Sarcoptes scabiei infestation using line‐field confocal optical coherence tomography
Get PDFBibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung
No full textDieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
In vivo microvascular imaging of cutaneous actinic keratosis, Bowen's disease and squamous cell carcinoma using dynamic optical coherence tomography
Get PDFBackground: A clear distinction between actinic keratosis (AK), Bowen's disease (BD) and squamous cell carcinoma (SCC) cannot reliably be made by clinical and dermoscopic evaluation alone. Dynamic optical coherence tomography (D-OCT) is a novel angiographic variant of OCT that allows for non-invasive, in vivo evaluation of the cutaneous microvascular morphology. Objective: To investigate the microvascular structures of AK, BD and invasive SCC using D-OCT in order to gain insights into the microvascular morphology of lesions in the spectrum of keratinocyte skin cancers. Methods: Forty-seven patients with a total of 54 lesions (18 AK, 12 BD and 24 SCC) were included in the study. D-OCT still images of AK, BD and SCC at three predefined skin depths were prepared and randomized, creating a study set of 162 D-OCT images. Three observers performed blinded evaluations of the randomized study set assessing multiple parameters including the different types of vascular morphology. Non-blinded quantitative measurements of vascular diameter were also performed. Results: The blinded observer analysis suggests that D-OCT evaluation of the vascular morphology may aid in distinguishing AK, BD and SCC lesions. We identified two vascular shapes that presented significantly differently across the lesion types, namely âblobsâ and âcurvesâ. A strong presence of blobs at 300 Î1⁄4m skin depth was characteristically seen in a third of BD cases, while not or only slightly present in AK and SCC lesions. Vascular curves were predominantly present in AK lesions. Conclusion: We identified various vascular D-OCT features that may aid in non-invasively differentiating subtypes within the keratinocyte skin cancer spectrum
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3346: Samuel G. Freedman, author, 2013
No full textPhotograph of author Samuel G. Freedman, at NT Daily Slash meeting in the Mayborn School of Journalism at UNT
Mergers Among German Cooperative Banks. A Panel-based Stochastic Frontier Analysis
Get PDFBased on an unbalanced panel of all Bavarian cooperative banks for the years of 1989-97 which includes information on 283 mergers, we analyze motives and cost effects of small-scale mergers in German banking. Estimating a frontier cost function with a time-variable stochastic efficiency term we show that positive scale and scope effects from a merger arise only if the merged unit closes part of the former branch network. When we compare actual mergers to a simulation of hypothetical mergers, size effects of observed mergers turn out to be slightly more favorable than for all possible mergers. Banks taken over by others are less efficient than the average bank in the same size class, but exhibit on average the same efficiency as the acquiring firms. For the post-merger phase, our empirical results provide no evidence for efficiency gains from merging, but point instead to a leveling off of differences among the merging units.banking, mergers, efficiency, stochastic frontier
Non-invasive real time imaging of mite skin infestation with line field confocal optical coherence tomography
No full textIntroduction
Mites affecting humans remain a widespread health issue. Among others, dermatologists need to deal with biting mites vectoring scrub thypus, house dust mites causing type I sensitisation, Sarcoptes scabiei as a vector of scabies and Demodex folliculorum associated to rosacea and Demodex folliculitis. Diagnosis is based on clinical features, skin scraping cannot always be performed. Scabies is a contagious, globally wide spread human skin infection. Caused by the scabies agent ectoparasite Sarcoptes scabiei var. hominis, its frequently occurring outbursts in communities lead to a significant health as well as economic burden. The process of diagnosing scabies is based on characteristic clinical features like a progressive rash or inflammatory excoriated papules. Moreover, the use of dermoscopy allows to visualize typical dermoscopic signs of a scabies infestation, for instance the so-called “delta”, “kite” or “triangle”, representing the anterior body of an adult female mite at the end of a burrow.
Identifying mites, eggs or faecal pellets through skin scraping, with the help of a high magnification device or dermoscopy are already established criteria to diagnose scabies.
Furthermore reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) have already been used to non-invasively detect scabies infestations. In addition to that, the new diagnostic imaging device Line-field confocal coherence tomography (LC-OCT) is not only able to provide a painless, real-time bedside visualisation of scabies mites inside human skin but also allows their therapeutic monitoring.
Material and Methods
Based on a two-beam interference microscope with line illumination and line detection scans with a cellular resolution (1.1 μm x 1.3 μm) can be provided. The device has three different imaging modalities: en-face, en-coupe and 3D.
Results
By using the en-coupe mode and 3D reconstruction, the exact location of the mite inside the epidermis and the Stratum corneum can be discovered. S. scabiei appear as an ovoid structure with a thin, corrugated exoskeleton and triangular spicules. Additionally, the detection of skybala and eggs as roundish, mainly hyperreflective structures, is possible.
Demodex mites are visible inside the hair follicles, in vertical mode as elongated hyperrefrective structures, while in en-face mode as solitary or more frequently multiple, roundish, hyperreflective structures.
Discussion
Non-invasive in-vivo examination of mites is able to provide a fast, painless diagnosis at bedside. An advantage of LC-OCT in comparison to conventional OCT is a higher, almost cellular resolution. Although its resolution is still lower than in RCM scans, the opportunity to combine the en-face mode with the en-coupe mode and the 3D imaging modality allows a high resolution and penetration depth. Besides detecting burrows, eggs and skybala, LC-OCT allows exact special correlations and measurement of structures. As a result immediate diagnosing of scabies and Demodex infestation and non-invasive therapeutic monitoring is possible. Therefore we see a high potential in the use of LC-OCT in the daily dermatologic practice in the future, with its diagnostic value not only limited to skin cancer diagnostics but also to be used in skin infestations
The concentration of console surgeons: prospective evaluation of the loss of attention in robotic-assisted procedures
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