1,721,266 research outputs found

    Children's 'place' in the development of neighbourhood social capital

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    The restrictions many parents place on children’s spatial freedoms are often tied to concerns about ‘urban risk’. Concurrently, those children afforded greater spatial autonomy are often represented as threatening and disruptive to local social interaction. Little research has, however, explored the implications of children’s spatial freedoms on social cohesion. Framed by the concept of social capital, this paper examines the role children play in developing the kinds of connection and relationship that build social networks, trust and neighbourliness. Focusing on children’s lives in three inner- city and two suburban locations in England, the paper explores neighbourhood social capital in relation to two ‘critical interactions’: first, between social policy, parenting values and children’s autonomy and, secondly, between children’s and parents’ local engagement

    Genetic and clinical aspects of X-linked hydrocephalus (L1 disease): Mutations in the L1CAM gene

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    L1 disease is a group of overlapping clinical phenotypes including X-linked hydrocephalus, MASA syndrome, spastic paraparesis type 1, and X-linked agenesis of corpus callosum. The patients are characterized by hydrocephalus, agenesis or hypoplasia of corpus callosum and corticospinal tracts, mental retardation, spastic paraplegia, and adducted thumbs. The responsible gene, L1CAM, encodes the L1 protein which is a member of the immunoglobulin superfamily of neuronal cell adhesion molecules. The L1 protein is expressed in neurons and Schwann cells and seems to be essential for nervous system development and function. The patients' gene mutations are distributed over the functional protein domains. The exact mechanisms by which these mutations cause a loss of 1,1 protein function are unknown. There appears to be a relationship between the patients' clinical phenotype and the genotype. Missense mutations in extracellular domains or mutations in cytoplasmic regions cause milder phenotypes than those leading to truncation in extracellular domains or to non-detectable L1 protein. Diagnosis of patients and carriers, including prenatal testing, is based on the characteristic clinical picture and DNA mutation analyses. At present, there is no therapy for the prevention or cure of patients' neurological disabilities. Hum Mutat 18:1-12, 2001. (C) 2001 Wiley-Liss, Inc

    Understanding the public voices and researchers speaking into the 5G narrative

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    The many different voices speaking into the current narrative surrounding the health effects of 5G technologies necessitate an exploration of the background of the various published author-spokespersons and their potential motives. This has been attempted recently by de Vocht and Albers. However, that opinion piece used a narrow investigative lens, resulting in an undermining of both the rationality of the concerned general public and the motives of specific researchers. At the same time, biases, conflicts of interest, and flaws found in “independent” reviews were not considered. To address these oversights, an evidence-based appraisal of public opinion and the scientific caliber of authors involved in the 5G health discussion is warranted. Subsequently, this review article presents an analysis of the available Australian data representing public voices, while also conducting a broader investigation of the level of expertise of recent author-spokespersons based on their experience as scientists, particularly in the area of health effects of radiofrequency electromagnetic fields. This review thus attempts to more clearly illustrate for the reader the caliber and motives of the voices speaking into the 5G narrative. The article concludes with a set of questions that need to be answered to enable scientists to advise policy makers more effectively on matters of 5G and public health.Full Tex

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Shifting analytic ontology: using I-poems in qualitative longitudinal research

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    In this article we highlight the way that different qualitative analytic methods implicitly place the interpretive analyst in different sorts of relationship to their interview subject and their data. The process of data analysis constructs an analytic mode of being in relation to the interviewee and their social reality. In particular, we illustrate this point through a detailed consideration of the analytic process involved in producing I-poems from qualitative longitudinal interview data (derived from Gilligan and colleagues' 'Listening Guide'), to explore change and continuity in a case study young person's sense of self over time. We contrast how we understood those changes and continuities through the different analytic angles provided by the gaze of thematic analysis and the voices identified through I-poems
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