674 research outputs found
Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis
No full textScarman, Anthony L.; Hooper, John D.; Boucaut, Kerry J.; Mae-Le Sit; Webb, Graham C.; Normyle, John F.; Antalis, Toni M
Development of a novel test rig for the evaluation of aircraft fuel tank sealants
No full textLeaks from aircraft fuel tanks have always represented a problem for aircraft manufacturers, airline operators and maintenance crews. The integral fuel tanks within aircraft structures are typically located within the wings and they rely upon sealant materials to prevent leakage past joints and fasteners. However, the wing is designed as a structural member first and as a fuel tank second and there exist many potential leak paths for the fuel from these complex, highly loaded structures. Fuel leaks result in direct loss of fuel which may be dangerous, cause a loss in revenue due to aircraft being withdrawn from service and be difficult and expensive to repair. On top of this there are important health and safety issues involved in the repair of fuel tanks, for example, the Royal Australian Air Force's, F-lll Deseal Reseal Programme 1979 to 2000, where it was found that a significant number of RAAF personnel involved in the Deseal Reseal Programme were suffering from a variety of health problems.
Current approaches to fuel tank sealant evaluation embrace immersion in a range of different fluids at different temperatures, of both bulk sealant samples and sealed joints. However, nearly all such tests are of a "static" nature and yet it is acknowledged that joint movement leads to leaks. Thus the missing component of testing is movement coupled with the other key variables. The aircraft industry has been searching for a relatively simple test method that can be used to evaluate sealed joint systems using realistic combinations of materials, joint geometries, imposed stresses and environmental conditions. The aim of this project was to do exactly this.
A practical but realistic dynamic test, the Model Sealed System (MSS), was designed, made and evaluated. This unique mechanism consists of an axial stress machine into which fatigue, high and low temperatures and pressures can be programmed for automatic operation. A novel circular lap joint lies at the heart of the MSS in which test sealant is sandwiched between the circular coupons that are then assembled with aerospace fasteners and sealed. This joint configuration is representative of a wing skin butt-strap joint in a real aircraft. The MSS is easy to run, it accurately simulates real world dynamics and conditioning, and it provides results to qualify sealants in a more realistic manner than current testing methods provide. The MSS enables evaluation and comparative testing of sealant systems when used
for interfay, fillet and overcoat applications. The information provided is complementary to that obtained from conventional small scale coupon testing; it is not seen as a substitute. Further work is required to refine the test variables and further data are required to provide confidence in the utility of the MSS.
Development of the MSS was undertaken with the support of Airbus UK to ensure that the design, materials and all other variables met with the overall requirements of a commercial aircraft manufacturer. Airbus UK have a duplicate MSS of their own, installed by the author, from which they can obtain patterns of data for different combinations of materials and experimental variables
Optimising a targeted test reduction intervention for patients admitted to the intensive care unit: the Targeted Intensive Care Test Ordering Cluster Trial intervention
No full textAbstract not available.Edward Litton, Helen Atkinson, James Anstey, Matthew Anstey, Lewis T. Campbell, Andrew Forbes, Rebecca Hahn, Katherine Hooper, Jessica Kasza, Sharon Knapp, Forbes McGain, Nhi Ngyuen, David Pilcher, Benjamin Reddi, Chris Reid, Suzanne Robinson, Kelly Thompson, Steve Webb, Paul Youn
Hamacantha (Vomerula) novacula Ekins & Baker & Hooper 2023, sp. nov.
No full textHamacantha (Vomerula) novacula sp. nov. Ekins & Hooper Figures 1, 3, Tables 1, 2 urn:lsid:zoobank.org:act: 49DB7D5B-D49D-4494-B476-65B74F0ABFFD Material examined: Holotype, QM G337915, Seamount, ridge near summit of South Recorder Guyot Seamount, Queensland, Australia, -25.13, 154.9983, 880–1100 m, Rock dredge, TMD-22MNF-SS 2012-V07, Coll. Greg Webb on RV Southern Surveyor, 8/XII/2012. Paratype, QM G326453, Cascade Seamount, Tasmania, Australia, -43.8613, 150.4286, 800–1000 m, SS 0207-066-029, Coll. A. Williams and M. Schlacher on RV Southern Surveyor, SS 02/ 2007, 9/IV/2007. Paratype, QM G324761, Andy’s Hill, Tasmania, Australia, -44.175, 146.98833, 881–1154 m, Sled— Benthic, Solenosmilia habitat, SS 01/97, Coll. T. Koslov, on RV Southern Surveyor, 29/I/1997. Etymology: L. novacula, f. shaving knife, in reference to the extra sharp fimbriae of the large diancistras. Description: The holotype is a fragile, lace-like, encrusting sponge, attached to a rock (Fig. 3A). It was originally 45 mm long, 25 mm wide and 2 mm in height. It has a smooth velvety surface, with no remaining obvious oscules. The aquiferous are clearly visible through the transparent ectosome. The prevalent circular ostia form rows on the surface (Figs. 3A,B). They are 0.3 mm in diameter, often with protective sharp tips from the styles and (Fig. 3 B, C). The areas between the ostia are visible as semitransparent lines where the spicules are not clustered, giving the appearance of a suburban street network (Fig. 3A). The sponge is white and translucent on deck and after preservation. The paratype QM G326453 is also growing on a rock, but paratype QM G324761 is growing on on Solenosmilia variabilis. Skeleton: The ectosomal skeleton is composed of tangential styles, arranged in a multispicular reticulated pattern around the circular ostia. The supportive styles from the choanosome pass through the ectosomal layer to provide a protective perimeter around the ostia. The small diancistras (II) sometimes occur in the very thin (2 µm) ectosomal layer, where the randomly sparsely scattered styles occur between the ostia. The choanosomal skeleton consists of bundles of ascending twisting columns of styles supporting the ectosomal layer and penetrating through the ectosome to produce the hispid surface (Fig. 3C). Both diancistras occur in these waisted twisted columns (Fig. 3C). Spicules: The megascleres are styles, which are abundant, fusiform, straight, sharply pointed, and thickest in the centre (Fig. 3I). The blunt end is much narrower than the middle and has a rounded style end (see Table 1 for measurements). The large diancistras (I) are common, twisted at about 70 o, the thin sharp fimbriae are very short on the inner shaft on a raised support. The fimbriae on the corresponding face of the hook is easily twice as long. Both faces have such an obvious sharp blade, with the appearance of a razor blade inserted into a razor blade holder (Fig. 3D). The smaller diancistras (II) are also common, they have sharp opposing alae with a reverse barb, thus resembling a fishhook (Fig 3F). An example of the reverse barb missing on some of the smaller diacistras was found on one of the specimens (QM G326453) (Fig. 3H). Rare examples were found of ‘teeth’ on the smaller diancistras on one of the specimens (QM G324761) (Fig. 3G). The small diancistras only have a small shaft twist of approximately 15 o (Fig. 3F). The sigmas are rare, thin and have a similar C shape to the small diancistras (Fig. 3E). One of the paratypes (QM G324761) also had tylostyles and subtylostyles, but these could not be found in the section and are considered non-native. Remarks: The new species H. (V.) novacula sp. nov. is very similar to the closely related species of H. (V.) acerata and H. (V.) umisachii. It differs from these two species most obviously be the shape of the large diancistras. This is also the main difference between H. (V.) acerata and H. (V.) umisachii. The shape and arrangement of the fimbriae is unique for the different species and consistent within the new species. The smaller diancistras (II) of the new species are similar in shape and the presence of a reverse barb is also similar to those of H. (V.) acerata and H. (V.) umisachii. The diancistras (II) of the new species are generally larger and lack the additional formations around the centre of the diancistras that usually occur in H. (V.) acerata (Fig. 2C). The sigmas are larger in the new species and in H. (V.) umisachii compared to H. (V.) acerata. The styles in the new species are longer and more tapering at the tyle end than those of H. (V.) umisachii and H. (V.) acerata.Published as part of Ekins, Merrick, Baker, Soraya & Hooper, John N. A., 2023, First records of Hamacantha species from seamounts off eastern Australia (Porifera, Demospongiae, Merliida), with description of four new species, pp. 382-400 in Zootaxa 5318 (3) on pages 385-388, DOI: 10.11646/zootaxa.5318.3.4, http://zenodo.org/record/816694
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Peer Victimization and Adolescent Substance Use: The Moderating Roles of Gender and Peer Aggression
No full textPeer victimization (PV) is a salient interpersonal stressor that has been linked with a variety of mental and physical health outcomes in adolescence. However, limited research has focused on the links between PV and substance use, specifically cigarette and alcohol use. The present study examined the relationship between four subtypes of PV (overt, relational, reputational, and cyber) and adolescent cigarette and alcohol use. Gender and peer aggression were also examined as potential moderators. Participants were 811 adolescents aged 13 to 19 years (M = 15.79 years; SD = 1.21), who were recruited from two high schools in the Miami-Dade County Public School system. Adolescents completed the Revised Peer Experiences Questionnaire, the Cyber Victimization Scale for Adolescents, and items from the Youth Risk Behavior Survey. Results indicated that aggressive boys who reported high levels of overt PV and aggressive boys who reported low levels of relational PV were most likely to report greater cigarette use. Overtly victimized youth were more likely to report a higher frequency of drinking and binge drinking. Cyber victimization represented a risk factor for all health risk behaviors. Findings suggest important targets for prevention and intervention efforts to reduce cigarette and alcohol use among youth. Peer-based interventions that address issues related to PV may be important in reducing adolescent substance use.</p
Biochemistry / David Hames and Nigel Hooper.
No full textPreviously published in 2000 as: Instant notes.Includes bibliographical references (p. 419-424) and index.vi, 438 pages. :A major update of the highly popular second edition, with changes in the content and organisation that reflect advances in the subject. As with the first two editions, the third edition of Instant Notes in Biochemistry provides the essential facts of biochemistry with detailed explanations and clear illustrations. It also includes new and expanded topics such as cytoskeleton, molecular motors, bioimaging, biomembranes, cell signaling, protein structure and enzymes regulation
Abyssocladia annae Ekins & Erpenbeck & Hooper 2020, sp. nov.
No full textAbyssocladia annae sp. nov. Figure 4, Table 1 urn:lsid:zoobank.org:act: E572DF22-EF0F-406D-B053-C20C0A5F84EA Material Examined: Holotype: QM G337611, off the continental shelf of central New South Wales, Australia, Station 88, 30° 15’ 50.4”– 30° 17’ 12.2” S, 153° 52’ 12”– 153° 49’ 48.7” E, 4481– 4401 m, Beam Trawl, Coll. Merrick Ekins on RV Investigator, Cruise IN2017_ V03, Sample 88–141.1 6/vi/2017. Etymology: Named after the loving memory of Anne Ekins and Anna Nelson, both of whom instructed the senior author about the beautiful design in nature. Distribution: This species is currently known only from the central coast of New South Wales, Australia, at abyssal depth. Description: Growth form: The holotype consists of the remains of a stem supporting a slightly cupped obovate (leaf-like, flabellate, fan-shaped) apical body (Figure 4 F). The body is hispid, with bundles of spicules radiating out only over a 90° quadrant. The specimen is 3 mm long x 2 mm wide. Colour: Beige on deck and beige in ethanol. Ectosomal skeleton: Thin membranous layer encrusted with abyssochelae. Endosomal skeleton: The axis of the stem consists of longitudinally arranged subtylostyles. The main body consists of radiating bundles of subtylostyles, undifferentiated from those of the stem. Megascleres: Subtylostyles are long and straight, thickest in the centre with a sharp tip (288-(504)- 1000 x 3.1- (7.4)-15.2 μm, n=49). Microscleres: Abyssochelae isochelae with obvious ridge and curved triangular shaft. (48.2-(60.6)-72.2 x 5.1- (9.7)-14.9 μm, n=45). Sigmancistras (11.6-(15.6)-18.5 x 0.9-(1.3)-1.8 μm, n=54). Molecular data: It was not possible to get unambiguous molecular data from the type material. Remarks: The shape of this species resembles one of the distal ends of the branches of A. koltuni Ereskovsky & Willenz, 2007 from the Sea of Okhotsk. However, A. annae sp. nov. lacks the large filament-forming mycalostyles that radiate from the oval bodies of A. koltuni, and also differs in lacking sigmas and having only a single size class of abyssochelae, which presents a very different shape to the isochelae of A. koltuni (Table 1). The gross morphology of this new species also superficially resembles that of the distal parts of A. hemiradiata Hestetun et al., 2017a from the SW Indian Ocean Ridge, but differs in having the slightly cupped morphology, with mainly bundles of subtylostyles radiating in one quadrant only. Abyssocladia annae sp. nov. also lacks the larger and thicker styles and the sigmas of A. hemiradiata, and has much larger sigmancistras (Table 1). Most obvious in this new species is the much larger and highly ridged abyssochelae. The only other Abyssocladia with similar chelae is A. brunni Lévi, 1964 from the Kermadec Trench. Abyssocladia annae sp. nov. differs in morphology from A. brunni which has a stem supporting a pedunculate spherical body heavily echinated by large lateral filaments up to 13 mm in length, as described both in Lévi (1964) and Koltun (1970). In addition, the current species also has smaller isochelae of a different shape (which Lévi 1964 terms ‘thaumatochetes’), sigmancistras only half the size, and smaller subtylostyles than those of A. brunni. In addition, A. brunni has styles, with only few showing slight subtylote basal swelling. The two known specimens of A. brunni described by Lévi (1964) and Koltun (1970) are possibly two different species. Abyssocladia annae sp. nov. also differs from A. natushimae Ise & Vacelet, 2010 from the Izu-Ogasawara Arc, in lacking filaments that echinate the main body, and the absence of styles, strongyles, and substrongyles and microstrongyles found in the Japanese species (Table 1).Published as part of Ekins, Merrick, Erpenbeck, Dirk & Hooper, John N. A., 2020, Carnivorous sponges from the Australian Bathyal and Abyssal zones collected during the RV Investigator 2017 Expedition, pp. 1-159 in Zootaxa 4774 (1) on pages 23-25, DOI: 10.11646/zootaxa.4774.1.1, http://zenodo.org/record/382514
Explorations of structure and choice in taxing capital gains: New Zealand tax experts' perspectives
No full textThis study explores the key issues, aspects, and attributes concerning capital gains tax (CGT) to enable the formulation of policy guidelines that might be used if a CGT were considered in New Zealand. It contends that the development of the New Zealand’s policy on taxing capital gains has continued in a somewhat ad hoc and inconsistent fashion. The lack of a uniform approach to capital gains taxation has resulted in detailed, but complex, legislation which leads to “policy inconsistencies and unintended incentives built into the tax structure” (Oliver, 2001, pp. 80 – 81). The study bridges the divide between theoretical analysis of CGT and implementation issues on operating a CGT. It attempts to address one primary research question and an associated secondary question. The primary research question is: should capital gains be taxed more comprehensively than at present? As a start, it examines the two important issues surrounding income definition and the capital/income distinction. In this regard, the research first attempts to identify the definition(s) of capital gains from the New Zealand perspective(s). This is followed by investigating the key areas of the tax system in order to seek the best way of taxing capital gains. This study also attempts to address the secondary research question, i.e., why (or why not) do the tax experts favour (or oppose) a comprehensive CGT? In this respect, this study identifies 23 factors/issues that are related to the tax experts’ attitudes towards a particular form of a CGT model (i.e., current hybrid approach, a realisation-based CGT or an accrual-based CGT). A mixed-methods design has been adopted in this study involving both a quantitative (survey) and a qualitative (interview) method in analysing the data to determine the tax experts’ overall perceptions of a CGT in New Zealand and the CGT adoption factors which influenced them. One important finding of the comparative analyses was that all tax experts generally agreed that the lack of a comprehensive CGT could provide more significant tax planning opportunities. However, many tax experts did not support the comprehensive income concept as they disagreed with the benefits derived from the gains in horizontal equity through adopting a CGT. This study has identified several important policy issues and reviewed their implication for the adoption of a CGT in New Zealand. The finding of the study revealed that the tax experts strongly supported the exemption of the gains on disposal of a taxpayer’s main residence and the tax preference for inflation adjustment. Another important policy issue is the implementation of an accrual-based CGT. Most tax experts considered a realisation-based CGT would be better than an accrual one. In particular, they were concerned about the liquidity problems and the compliance costs involved in an accrual-based CGT regime i.e., the annual valuation of all assets. These findings represent a first step towards a theoretical CGT framework. It is hoped that the knowledge gained in this study would give a greater understanding into the practical decision-making process that could result in a better public acceptance for a tax reform
Promoting academic library resources within a course management system: partnering with faculty
No full textSource type: Prin
Lycopodina nikitawimandi Ekins & Erpenbeck & Hooper 2020, sp. nov.
No full textLycopodina nikitawimandi sp. nov. Figures 27 & 28, Tables 14 & 16 urn:lsid:zoobank.org:act: F5AAEA15-DBAF-4A21-A2B9-E336733E613D Material examined: Holotype QM G337534 off Freycinet Peninsular, Tasman Sea, Station 11, Tasmania, Australia, 41° 43’ 14.5”S, 149° 7’ 30.7” E, 2793 m, Box Corer, Coll. Merrick Ekins on RV Investigator, Cruise IN2017_ V03, Sample 11-110.2, 19/v/2017, growing on a skeleton of a hexactinellid. Paratypes: QM G337510 same collection details and hexactinellid skeleton as for holotype, Sample 11-110.1; QM G337537 same collection details and hexactinellid skeleton as holotype, Sample 11-110.3; QM G337549 same collection details and hexactinellid skeleton as holotype, Sample 11-110.4; QM G337197 same collection details as holotype but on a different hexactinellid skeleton, Sample 11-120.1; QM G337514 off Central New South Wales, Tasman Sea, Station 89, New South Wales, Australia, 30° 15’ 47.9”– 30° 17’ 21.5” S, 153° 51’ 31.3”– 153° 50’ 37.7” E, 4436– 4414 m, Brenke Epibenthic Sledge, Coll. Merrick Ekins on RV Investigator, Cruise IN2017_ V03, Sample 89-129, 6/vi/2017, growing on worm tubes. Etymology: Named for the son of the first author, Nikita Wimandi Ekins. Distribution. Central East coast and central Tasmania, Tasman Sea, Australia, at bathyal to abyssal depths. Description: Growth form: This sponge is an erect stipitate sponge with filaments radiating in all directions projecting from the cylindrical stalk (Figures 27 A, 28 C). The body is 28 mm in length and 1–2 mm in width. The filaments are 2–3 mm in length and between 50–250 µm in width, and cover approximately 80% of the upper stem. The sponge has a spherical basal region of 3 mm diameter, with protruding smaller mycalostyles (Figure 28 F). This basal holdfast region grows within a hard or consolidated substrate. Many specimens appear to be a 2 dimensional feather due to damage sustained during collection. Colour: Pale cream on deck and in ethanol. Ectosomal skeleton: The ectosomal skeleton is thin and membranous and contains the anisochelae (Figure 28 E). Endosomal skeleton: The axis of the peduncle and the filaments consist of bundles of mycalostyles longitudinally arranged (Figure 28 D). Megascleres: Large mycalostyles only occurring in the main axis (1040–1910 x 12–37 µm, n=132) (Figure 27 C–D). Smaller mycalostyles consistent throughout the sponge including the filaments and basal holdfast (209–992 x 3–19 µm, n=250) (Figure 27 E–F) (see Table 16) * Most of the specimen disappeared off the SEM stub before the measurements of the large styles, which were present, could be made. Microscleres: Palmate anisochelae with the frontal upper alae nearly fully detached from the two lateral alae, and the three lower alae nearly completely fused to each other and the fimbria, with the frontal lower alae bearing three terminal spines and each of the lateral alae with two terminal spines (9–18 µm (length) x 2–6 µm (large alae width), 3–4 µm (small alae width), n=258) (Figure 27 B) (see Table 16). Molecular data: The 28 S sequences of QM G 337197 and QM G 337534 are provided in the Sponge Barcoding Database under accession numbers SBD#2304, SBD#2305 respectively and the molecular difference to other congenerics displayed in Figure 3. Remarks: Of the 29 described species of Lycopodina six have stipitate growth form, numerous large filaments along most of the stem, an enlarged basal attachment (where known), and only simple spiculation of styles or mycalostyles as structural megascleres, and palmate anisochelae as microscleres (Table 14). Lycopodina drakensis Goodwin, Berman, Downey & Hendry, 2017, also has forceps microscleres, and the shorter mycalostyles occur in the stem and the longest ones in the filaments, the opposite of those in L. nikitawimandi sp. nov. Lycopodina lycopodium (Levinsen, 1887) and L. occidentalis (Lambe, 1893) have a similar distribution of short and long styles in the stem, body, filaments and basal attachment, but these are generally smaller than those of the new species, and both species also have forceps microscleres. Lycopodina robusta (Levinsen, 1887) has significantly smaller styles and also possesses forceps, L. tendali Hestetun et al., 2017 has larger styles that are uniformly distributed and forceps, and L. vaceleti (Van Soest & Baker, 2011) has similar mycalostyles in the stem as L. nikitawimandi sp. nov., but also has a second category of smaller styles in the filaments and body, two categories of anisochelae, one of which has a unique sigma-like shape, and forceps microscleres (Table 14).Published as part of Ekins, Merrick, Erpenbeck, Dirk & Hooper, John N. A., 2020, Carnivorous sponges from the Australian Bathyal and Abyssal zones collected during the RV Investigator 2017 Expedition, pp. 1-159 in Zootaxa 4774 (1) on pages 141-144, DOI: 10.11646/zootaxa.4774.1.1, http://zenodo.org/record/382514
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