2,636 research outputs found

    Supplemental Material - The roles of environmental conditions in the pollutant emission-induced gross primary production change: Co-contribution of meteorological fields and regulation of its background gradients

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    Supplemental Material for The roles of environmental conditions in the pollutant emission-induced gross primary production change: Co-contribution of meteorological fields and regulation of its background gradients by Xuan Gui, Lunche Wang, Qian Cao, Shiyu Li, Weixia Jiang, and Shaoqiang Wang in Progress in Physical Geography: Earth and Environment</p

    Online_supporting_document – Supplemental material for Cognitive Diagnostic Models With Attribute Hierarchies: Model Estimation With a Restricted Q-Matrix Design

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    Supplemental material, Online_supporting_document for Cognitive Diagnostic Models With Attribute Hierarchies: Model Estimation With a Restricted Q-Matrix Design by Dongbo Tu, Shiyu Wang, Yan Cai, Jeff Douglas and Hua-Hua Chang in Applied Psychological Measurement</p

    Supplemental Material - The evolution of open biomass burning during summer crop harvest in the North China Plain

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    Supplemental Material for The evolution of open biomass burning during summer crop harvest in the North China Plain by Shiyu Li, Ming Zhang, Lunche Wang, Qian Cao, Wenmin Qin in Progress in Physical Geography: Earth and Environment</p

    sj-docx-1-tct-10.1177_15330338231167249 - Supplemental material for DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer

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    Supplemental material, sj-docx-1-tct-10.1177_15330338231167249 for DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer by Yanguang Hou, Jiachen Liu, Shiyu Huang, Lei Wang, Juncheng Hu and Xiuheng Liu in Technology in Cancer Research & Treatment</p

    sj-docx-2-tct-10.1177_15330338231167249 - Supplemental material for DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer

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    Supplemental material, sj-docx-2-tct-10.1177_15330338231167249 for DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer by Yanguang Hou, Jiachen Liu, Shiyu Huang, Lei Wang, Juncheng Hu and Xiuheng Liu in Technology in Cancer Research & Treatment</p

    Yong wai xie de fang shi xu shuo quan bu de shi shi: lun "jing shen fen lie zheng" yu hou zi ben zhu yi she hui de ying xiang wen hua

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    Gao, Shiyu.Thesis M.F.A. Chinese University of Hong Kong 2014.Includes bibliographical references (leaves 46-48).Abstracts also in Chinese.Title from PDF title page (viewed on 16, December, 2016).Gao, Shiyu

    sj-docx-1-tam-10.1177_17588359231206274 – Supplemental material for Efficacy and safety of anti-PD-1 monotherapy versus anti-PD-1 antibodies plus lenvatinib in patients with advanced hepatocellular carcinoma: a real-world experience

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    Supplemental material, sj-docx-1-tam-10.1177_17588359231206274 for Efficacy and safety of anti-PD-1 monotherapy versus anti-PD-1 antibodies plus lenvatinib in patients with advanced hepatocellular carcinoma: a real-world experience by Qingyan Liu, Rong Li, Lingling Li, Gaokun Wang, Shiyu Ji, Xuan Zheng, Xiaodong Jia, Haitao Tao and Yi Hu in Therapeutic Advances in Medical Oncology</p

    sj-pdf-2-tam-10.1177_17588359231206274 – Supplemental material for Efficacy and safety of anti-PD-1 monotherapy versus anti-PD-1 antibodies plus lenvatinib in patients with advanced hepatocellular carcinoma: a real-world experience

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    Supplemental material, sj-pdf-2-tam-10.1177_17588359231206274 for Efficacy and safety of anti-PD-1 monotherapy versus anti-PD-1 antibodies plus lenvatinib in patients with advanced hepatocellular carcinoma: a real-world experience by Qingyan Liu, Rong Li, Lingling Li, Gaokun Wang, Shiyu Ji, Xuan Zheng, Xiaodong Jia, Haitao Tao and Yi Hu in Therapeutic Advances in Medical Oncology</p

    Initial Upper Palaeolithic material culture by 45,000 years ago at Shiyu in northern China

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    The geographic expansion of Homo sapiens populations into southeastern Europe occurred by ∼47,000 years ago (∼47 ka), marked by Initial Upper Palaeolithic (IUP) technology. H. sapiens was present in western Siberia by ∼45 ka, and IUP industries indicate early entries by ∼50 ka in the Russian Altai and 46–45 ka in northern Mongolia. H. sapiens was in northeastern Asia by ∼40 ka, with a single IUP site in China dating to 43–41 ka. Here we describe an IUP assemblage from Shiyu in northern China, dating to ∼45 ka. Shiyu contains a stone tool assemblage produced by Levallois and Volumetric Blade Reduction methods, the long-distance transfer of obsidian from sources in China and the Russian Far East (800–1,000 km away), increased hunting skills denoted by the selective culling of adult equids and the recovery of tanged and hafted projectile points with evidence of impact fractures, and the presence of a worked bone tool and a shaped graphite disc. Shiyu exhibits a set of advanced cultural behaviours, and together with the recovery of a now-lost human cranial bone, the record supports an expansion of H. sapiens into eastern Asia by about 45 ka

    Z-form DNA-RNA hybrid blocks DNA replication

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    We discovered that the Z-form DNA-RNA hybrid stabilized by methylated CpG repeats impacts on the initiation and elongation of Okazaki fragments, contributing to blocking DNA replication at first time. We further present the first Z-form DNA-RNA hybrid structure by using NMR spectroscopy and dynamic computation, revealing the molecular mechanism of inhibition, indicating that a distinctive zig-zag strand pattern of the Z-form hybrid with a smaller helical diameter (15 Å) and a very narrow minor groove (8.3 Å) plays the key role in the repression toward DNA replication.Citation: Shiyu Wang, Yan Xu, Z-form DNA-RNA hybrid blocks DNA replication, Nucleic Acids Research, 53(5), 2025-02-27, https://doi.org/10.1093/nar/gkaf13
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