16,556 research outputs found
Promalactis pileata Wang 2019
No full textPromalacti pileata Wang, 2019 Promalacti pileata Wang, 2019, in Wang & Liu: 289. TL: China (Hainan). TD: NKU. Material examined. Malaysia, Mt. Trusmadi, Sabah: 2 ♂, 1223 m, 10‒12.V.2019, coll. S Yu, slide No. LC 19125; 1 ♂, 1 ♀, 1223 m, 7‒11.II.2018, coll. MJ Qi; 1 ♀, 1223 m, 21.VII.2018, coll. KJ Teng, slide No. JYY17910. Distribution. China (Hainan), Malaysia. Notes. This species is recorded for the first time in Malaysia.Published as part of Liu, Chen & Wang, Shuxia, 2020, Genus Promalactis Meyrick, 1908 (Lepidoptera: Oecophoridae) from Malaysia with description of three new species in Zootaxa 4755 (1), DOI: 10.11646/zootaxa.4755.1.2, http://zenodo.org/record/372425
Integrated Parylene LC-ESI on a Chip
Get PDFIn this thesis, several microfluidic devices will be introduced to demonstrate the integration capability of a multilayer parylene surface micromachining technology. Due to its flexibility and versatility, various devices have been developed and integrated onto a single ship. Based on the technology, on-chip LC-ESI was successfully demonstrated.
Based on the technology, an electrostatically actuated micro peristaltic pump has been developed. An AC actuation voltage combined with a peristaltic actuation was used to demonstrate fluid pumping. A reasonable flow rate and pumping pressure were achieved. The pump dynamics and performance were then addressed further by an analysis based on a lumped-parameter model of the system.
Based on the same technology, an entirely surface micromachined electrostatically actuated valve has been demonstrated. A thermal flow sensor was integrated with the valve to be used for feedback control. Two modes, actuation voltage adjustment and PWM were investigated in characterizing the valve to control air flow. The testing results show that PWM has better linearity and performance.
Three types of capacitive fluidic sensors were demonstrated in several microfluidic applications. These include sensors for fluid pressure, flow rate, volume, and composition measurement. The sensors showed great promise for microfluidic applications because of their high sensitivity and easy integration capabilities. The integration of these sensors with abovementioned devices was achieved.
A novel electrochemical pumping system for on-chip LC gradient generation was demonstrated. This pump was able to deliver significant flow rates under high back pressures that are sufficient for many LC applications. On-chip gradient formation with integrated electrospray ionization was demonstrated.
Finally, a complete LC-ESI system was integrated in a chip format. Typical nano-LC reversed-phase gradient elution was demonstrated using on-chip electrolysis pump. Separated analytes from on-chip column were then sprayed into MS for analysis through an integrated ESI-nozzle. Separation results are comparable to those of commercial system. Peptide identification performance using the LC-ESI chip with MS was also very close to those achieved by the commercial system.</p
LC compensators for power factor correction of nonlinear loads
No full textThis material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. Copyright @ 2004 IEEEA method is presented for finding the optimum fixed LC compensator for power factor correction of nonlinear loads where both source voltage and load current harmonics are present. The LC combination is selected because pure capacitive capacitors alone would not sufficiently correct the power factor. Optimization minimizes the transmission loss, maximizes the power factor, and maximizes the efficiency. The performance of the obtained compensator is discussed by means of numerical examples
LC compensators based on transmission loss minimization for nonlinear loads
No full textThis material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. Copyright @ 2004 IEEEThis paper presents a method employing the penalty function search algorithm to determine the LC compensator value for the optimal power factor correction in nonsinusoidal systems. The objective of the proposed method is to minimize the transmission loss while the power factor and efficiency are taken as constraints and utilized in order to solve the multiobjective optimization problem by transforming it into a single objective one. Examples show that the load nonlinearity can have a significant impact on optimal compensator sizes
LC-API/MS in Drug Metabolism and Pharmacokinetic Studies
No full textThe use of API interfaces with quadrupole mass spectrometers has been shown to give rise to good sensitivity, selectivity, and robustness for the interfacing of LC to MS. Since their introduction in the 1990s the technique has rapidly become widespread, but at the outset of this research programme, there were still a number of problems associated with it, particularly when dealing with complex sample matrices. The aim of this research programme was to study illustrative examples of the kinds of problems associated with the analysis of biological samples using LC-API-MS in an attempt to arrive at strategies which could be employed to eliminate, or at least compensate for, the problems.
Commonly reported problems include the occurrence of matrix effects - a change in response of the target analyte(s) as a result of the presence in the samples of co /late eluting interferences. An investigation which compared ESI with APCI ionisation illustrated a significant drawback in the accepted methodology for the elimination of matrix effects.
Optimal LC conditions for a number of assays may use non-MS-friendly mobile phases. A simple and convenient solution to this problem was found to be the post column addition of organic modifier, which reproducibly and reliably enhanced sensitivity. This approach was initially used for a range of dihydropyridine calcium channel blockers and was subsequently applied to a range of chiral compounds from different therapeutic groups to illustrate that this was applicable as a generic technique for increasing sensitivity (typically by around an order of magnitude) in low organic mobile phases.
Strategies to develop and validate methods for the determination of endogenous analytes in a biological fluid were investigated. This involved the use of a surrogate matrix, to develop a method for the determination of endogenous testosterone in human serum and the use of non-matrix calibration standards for the successful development and validation of a method for the analysis of indolyl 3 acryloylglycine (IAG) in human urine.
As a result of observations suggesting promotion of ionisation of deltamethrin in liver tissue sample extracts, it was postulated that this was due to the presence of high concentrations of surfactants. After confirming the effect, a series of systematic investigations were performed to attempt to understand the mechanism to be able to utilise this as a general method for the enhancement of signal with low sensitivity analytes. It was found that the type of surfactant and concentration used was directly associated with an increased (or decreased) response.
Although there remain a number of problems associated with the use of LC-API-MS, the work undertaken for this thesis has successfully demonstrated a number of techniques that can be applied to overcome these problems. Knowledge of the nature of the sample undergoing analysis, the required analytical conditions, and where required careful application of one of the techniques described will ensure that a robust method can be readily developed
Apex Peptide Elution Chain Selection: A New Strategy for Selecting Precursors in 2D-LC-MALDI-TOF/TOF Experiments on Complex Biological Samples
Get PDFLC-MALDI provides an often overlooked opportunity to exploit the separation between LC-MS and MS/MS stages of a 2D-LC-MS-based proteomics experiment, that is, by making a smarter selection for precursor fragmentation. Apex Peptide Elution Chain Selection (APECS) is a simple and powerful method for intensity-based peptide selection in a complex sample separated by 2D-LC, using a MALDI-TOF/TOF instrument. It removes the peptide redundancy present in the adjacent first-dimension (typically strong cation exchange, SCX) fractions by constructing peptide elution profiles that link the precursor ions of the same peptide across SCX fractions. Subsequently, the precursor ion most likely to fragment successfully in a given profile is selected for fragmentation analysis, selecting on precursor intensity and absence of adjacent ions that may cofragment. To make the method independent of experiment-specific tolerance criteria, we introduce the concept of the branching factor, which measures the likelihood of false clustering of precursor ions based on past experiments. By validation with a complex proteome sample of Arabidopsis thaliana, APECS identified an equivalent number of peptides as a conventional data-dependent acquisition method but with a 35% smaller work load. Consequently, reduced sample depletion allowed further selection of lower signal-to-noise ratio precursor ions, leading to a larger number of identified unique peptides.
Ashoka raw data
No full textThis is the raw textual data of ashoka profiles. Please cite it as:
Chandra Y, Jiang LC, Wang C-J (2016) Mining Social Entrepreneurship Strategies Using Topic Modeling. PLoS ONE 11(3): e0151342. doi:10.1371/journal.pone.015134
Promalactis spinosicornuta Du & Wang 2013
No full text<i>Promalactis spinosicornuta</i> Du & Wang, 2013 <p>(Fig. 55)</p> <p> <i>Promalactis spinosicornuta</i> Du & Wang, 2013, <i>Zookeys</i>, <b>285</b>: 39. TL: China (Tibet). TD: IZCAS.</p> <p> <b>Material examined.</b> <b>Tibet</b>: 8♂, 3♀, Chengjiao, Motuo County, 1016 m, 4‒5.VIII.2018, leg. MJ Qi, slide Nos. LC 19318 ♀, LC19319 ♂, LC19778 ♀; 1♂, 80K, Motuo Road, Motuo County, 2076 m, 6.VIII.2018, leg. MJ Qi, slide No. LC 19322.</p> <p> <b>Description.</b> Female forewing length 5.0‒ 5.5 mm.</p> <p>Abdomen: Female genitalia (Fig. 55). Apophyses anteriores about half as long as apophyses posteriores. Eighth tergum sub-quadrangular, with sparse setae; eighth sternum rectangular, rounded and setose on posterior margin, incised in middle from posterior margin. Antrum cup-shaped, with a curved band arising from dorsal surface near posterior margin laterally. Ductus bursae long, coiled and scattered with several spines. Corpus bursae membranous, ovate, shorter than half length of ductus bursae; signum absent.</p> <p> <b>Distribution.</b> China (Tibet).</p> <p> <b>Notes.</b> The female is described for the first time.</p>Published as part of <i>Wang, Shuxia & Liu, Chen, 2021, Taxonomic study of the genus Promalactis Meyrick, 1908 (Lepidoptera: Oecophoridae) X. The commotica species-group, with descriptions of twenty-two new species, pp. 293-330 in Zootaxa 4980 (2)</i> on page 318, DOI: 10.11646/zootaxa.4980.2.4, <a href="http://zenodo.org/record/4889068">http://zenodo.org/record/4889068</a>
Ashoka raw data
No full textThis is the raw textual data of ashoka profiles. Please cite it as:
Chandra Y, Jiang LC, Wang C-J (2016) Mining Social Entrepreneurship Strategies Using Topic Modeling. PLoS ONE 11(3): e0151342. doi:10.1371/journal.pone.015134
LC-MS quantification of retinoic acid, resveratrol, and beta-carotene bioavailability and bioconversion to retinol.
No full textLC-MS quantification of retinoic acid, resveratrol, and beta-carotene bioavailability and bioconversion to retinol
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