5,810 research outputs found
Unihemispheric sleep and asymmetrical sleep: behavioral, neurophysiological, and functional perspectives [Corrigendum]
No full textMascetti GG. Nat Sci Sleep. 2016;8:221–38.For references 147, 153 and 154 the lead author should be Vyazovskiy, not Wyazovskiy.Read the original articl
Soft gluon resummation in the signal-background interference process of gg(→ h ∗) → ZZ
No full textWe present a precise theoretical prediction for the signal-background interference process of gg(→ h ∗) → ZZ, which is useful to constrain the Higgs boson decay width and to measure Higgs couplings to the SM particles. The approximate NNLO K-factor is in the range of 2.05 − 2.45 (1.85 − 2.25), depending on M ZZ , at the 8 (13) TeV LHC. And the soft gluon resummation can increase the approximate NNLO result by about 10% at both the 8 TeV and 13 TeV LHC. The theoretical uncertainties including the scale, uncalculated multi-loop amplitudes of the background and PDF+αs are roughly O(10%) at NNLL′. We also confirm that the approximate K-factors in the interference and the pure signal processes are the same
ASSIGNMENT OF , , and CONFORMERS IN THE ROTATIONAL SPECTRUM OF -PROPANOL
No full textAuthor Institution: Institute of Physics, Polish Academy of Sciences, Al. Lotnikow; 32/46, 02-668 Warszawa, Poland; Department of Physics, The Ohio State University, Columbus,; OH 43210Recent broadband measurements of the rotational spectrum of -propanol up to 375 GHz resulted in determination of precise spectroscopic constants for the conformer of this molecule.}, 428 (2006)} This is most likely the most stable conformer, although four other conformers are predicted to be very similar in energy. Assignment of some of these in cm-wave rotational spectra has previously been reported, but it was not possible to extend that work directly to mm-wave spectra. \vspace{0.2cm} Application of graphical Loomis-Wood techniques built into AABS}, 231 (2005)} and CAAARS}, 229 (2005)} spectral analysis packages eventually allowed successful assignment of the remaining four conformers: , , , and -propanol. It was realised that rotational energies in (, ) and (, ) pairs of conformers are highly coupled, but also amenable to description in terms of the Coriolis interaction mechanism. This allowed very precise determination of some energy level differences, such as cm. The assignment was checked against calculations, and is supported by new, precise determinations of dipole moments of some conformers, which were carried out using supersonic expansion cavity-FTMW spectroscopy
The long-wavelength view of GG Tau A: rocks in the ring world
No full textWe present the first detection of GG Tau A at centimetre wavelengths, made with the Arcminute Microkelvin Imager Large Array at a frequency of 16 GHz (λ = 1.8 cm). The source is detected at >6 σrms with an integrated flux density of S16GHz = 249 ± 45 µJy. We use these new centimetre-wave data, in conjunction with additional measurements compiled from the literature, to investigate the long-wavelength tail of the dust emission from this unusual protoplanetary system. We use an MCMC-based method to determine maximum likelihood parameters for a simple parametric spectral model and consider the opacity and mass of the dust contributing to the microwave emission. We derive a dust mass of Md ~ 0.1 Msun, constrain the dimensions of the emitting region and find that the opacity index at λ > 7 mm is less than unity, implying a contribution to the dust population from grains exceeding ~4 cm in size. We suggest that this indicates coagulation within the GG Tau A system has proceeded to the point where dust grains have grown to the size of small rocks with dimensions of a few centimetres. Considering the relatively young age of the GG Tau association in combination with the low derived disc mass, we suggest that this system may provide a useful test case for rapid core accretion planet formation models
Localization and discrimination of GG mismatch in duplex DNA by synthetic ligand-enhanced protein nanopore analysis
No full text: Mismatched base pairs in DNA are the basis of single-nucleotide polymorphism, one of the major issues in genetic diseases. However, the changes of physical and chemical properties of DNA caused by single-site mismatches are often influenced by the sequence and the structural flexibility of the whole duplex, resulting in a challenge of direct detection of the types and location of mismatches sensitively. In this work, we proposed a synthetic ligand-enhanced protein nanopore analysis of GG mismatch on DNA fragment, inspired by in silico investigation of the specific binding of naphthyridine dimer (ND) on GG mismatch. We demonstrated that both the importing and unzipping processes of the ligand-bound DNA duplex can be efficiently slowed down in α-hemolysin nanopore. This ligand-binding induced slow-down effect of DNA in nanopore is also sensitive to the relative location of the mismatch on DNA duplex. Especially, the GG mismatch close to the end of a DNA fragment, which is hard to be detected by either routine nanopore analysis or tedious nanopore sequencing, can be well differentiated by our ND-enhanced nanopore experiment. These findings provide a promising strategy to localize and discriminate base mismatches in duplex form directly at the single-molecule level
ATPase activity measurement of DNA replicative helicase from Bacillus stearothermophilus by malachite green method
No full textThe DnaB helicase from Bacillus stearothermophilus (DnaBBst) was a model protein for studying the bacterial DNA replication. In this work, a non-radioactive method for measuring ATPase activity of DnaBBst helicase was described. The working parameters and conditions were optimized. Furthermore, this method was applied to investigate effects of DnaG primase, ssDNA and helicase loader protein (DnaI) on ATPase activity of DnaBBst. Our results showed this method was sensitive and efficient. Moreover, it is suitable for the investigation of functional interaction between DnaB and related factors. (C) 2016 Elsevier Inc. All rights reserved
Triangular Constellations in Flows
No full textParticles advected on the surface of a fluid can exhibit fractal clustering. The local structure of a fractal set is described by its dimension , which is the exponent of a power-law relating the mass in a ball to its radius : . It is desirable to characterise the {\em shapes} of constellations of points sampling a fractal measure, as well as their masses. The simplest example is the distribution of shapes of triangles formed by triplets of points, which we investigate for fractals generated by chaotic dynamical systems. The most significant parameter describing the triangle shape is the ratio of its area to the radius of gyration squared. We show that the probability density of has a phase transition: is independent of and approximately uniform below a critical flow compressibility , which we estimate. For the distribution appears to be described by two power laws: when , and when
The distribution of the haplotypes defined by C<sup>987</sup>GG/G<sup>987</sup>GG and TAA<sup>1118</sup>/TAC<sup>1118</sup> according to CAG repeat number.
No full text<p>The distribution of the haplotypes defined by C<sup>987</sup>GG/G<sup>987</sup>GG and TAA<sup>1118</sup>/TAC<sup>1118</sup> according to CAG repeat number.</p
Forest plot of cancer risk associated with the rs2736098 polymorphism (AA vs. GG).
No full text<p>The rs2736098 polymorphism was associated with an increased risk of cancer in the homozygote comparison (AA vs. GG).</p
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