2,761 research outputs found
"Turning somersaults with a hand nailed to the floor:" Infinite Jest's recursive presentation of Waste-Desire Cycles by Anna Walsh.
No full textThesis: S.B. in Literature, Massachusetts Institute of Technology, Department of Humanities, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 54-55).S.B. in Literatur
Distal renal tubular acidosis: ERKNet/ESPN clinical practice points
No full textTrepiccione, F., Walsh, S.B., Ariceta, G., Boyer, O., Emma, F., Camilla, R., Ferraro, P.M., Haffner, D., Konrad, M., Levtchenko, E., Lopez-Garcia, S.C., Santos, F., Stabouli, S., Szczepanska, M., Tasic, V., Topaloglu, R., Vargas-Poussou, R., Wlodkowski, T., Bockenhauer, D
Stratified external mixing at moderate Richardson number
No full textStratified turbulent mixing remains an unsolved problem. Turbulent mixing is complicated by its intermittent nature, its highly vortical motion and the large range of scales of its coherent structures. In order to help reduce the problem to a more tractable form, we consider vortex rings as a reproducible, idealized form of a turbulent coherent structure of a defined length and velocity scale. We generate vortex rings in a stably stratified two-layer fluid of varying Richardson number and observe the vortex ring induced mixing. While previous work has looked at the effect of individual vortex rings on the stratified interface, we analyze the aggregate mixing induced over many vortex ring generations. Over successive vortex rings collisions, the mixing rate converges to a constant for a range of Richardson numbers
Policy Analysis of Special Immigrant Juvenile Status S.B. 873
No full textThe purpose of this paper was to conduct a policy analysis on California's S.B. 873 which was enacted in 2014 and focuses on unaccompanied immigrant minors. This population was narrowed to those entering the U.S. from Central American countries Guatemala, Honduras, and El Salvador. This analysis used an Intersectionality-Based Policy Analysis (IBPA) Framework. The results demonstrated that this population has multi-layered needs when going through immigration proceedings to which there are many barriers to being successful in achieving U.S. residency. Some of these barriers include, language barriers and lack of legal representation, economic hardships based on the lack of benefits available to them, and lack of trauma focused care. S.B. 873 challenges and provides money for legal representation to become more available, expands benefits that this population can qualify for, and provides a path to appoint guardianship. This policy analysis explored the gaps in S.B. 873 through an Intersectionality-Based Policy Framework. Through this analysis, the author offers recommendations for future care of unaccompanied minors as they deal with the immigration system.by Carolina Cardoz
Author Correction: New perspectives on Neanderthal dispersal and turnover from Stajnia Cave (Poland)
No full textThe Author contributions section now reads:“W.N., A.N. and S.T. designed research; A.P., M.H., W.N., S.B., M.U., A.M., H.F., M.D.B., P.S., K.S., M.Ż., A.W., A.N. and S.T. performed research; A.P., M.H., W.N., S.B., M.U., A.M., H.F., M.D.B., P.S., K.S., M.Ż., A.W., A.N. and S.T. analysed data; A.P., M.H., S.T., W.N. and S.B. wrote the paper with the collaboration of all the co-authors.
Author Correction:A 41,500 year-old decorated ivory pendant from Stajnia Cave (Poland)
No full textCorrection to: Scientific Reports https://doi.org/10.1038/s41598-021-01221-6, published online 25 November 2021The original version of this Article contained errors in the author list where Marjolein D. Bosch was omitted from the author list, and Mikołaj Urbanowski was incorrectly listed as an author of the original Article, and has subsequently been removed.The Author contributions section now reads:“S.T. W.N. and A.N. conceived the project; S.T., W.N., A.P., M.B., S.C., M.D., H.F., A.M., M.D. B., D.P., M.P.R., C.M.R., V.S-M., G.M.S., P.S., M.S., K.S., A.V., F.W., H.W., A.W., M.Z., S.B., A.N., J-J. H., performed research; S.T., A.P., W.N., M.B., M.D.B., S.C., M.D., H.F., A.M., D.P., M.P.R., C.M.R., V.S-M., G.M.S., P.S., M.S., K.S., A.V., F.W., H.W., A.W., M.Z., S.B., A.N., J-J. H. analysed all archaeological data; S.T. and A.P. wrote the paper with the collaboration of all the co-authors.”The original Article and its accompanying Supplementary Information file have been corrected
Implementation and performance of a database management system-based filesystem using size-varying storage heuristics
No full textThesis (M.Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2003.Includes bibliographical references (p. 63-65).by Eamon Francis Walsh.M.Eng.and S.B
Distal renal tubular acidosis developments in its diagnosis and pathophysiology
No full textThis thesis describes two groups of experiments, both relating to the
condition of distal renal tubular acidosis (dRTA).
In the first, an alternative diagnostic test of dRTA to the ‘gold standard’
short ammonium chloride (NH4Cl) test was assessed. This was achieved
by the simultaneous oral administration of the diuretic furosemide and
the mineralocorticoid fludrocortisone to increase distal sodium delivery
and a-intercalated cell proton secretion. I evaluated 11 control subjects
and 10 patients with known dRTA by giving oral NH4Cl or
furosemide/fludrocortisone in random order on separate days. 3
subjects were unable to complete the study due to vomiting after the
NH4Cl, however there were no adverse effects with
furosemide/fludrocortisone administration. The urine pH decreased to
less than 5.3 in the controls with both tests, whereas no patients were
able to lower their urine pH below 5.3 with either test. The simultaneous
administration of furosemide/fludrocortisone proved to be an easy,
effective and well-tolerated alternative to the standard NH4Cl test for the
diagnosis of dRTA.
The second group were laboratory-based molecular physiology
experiments. Anion exchanger 1 (AE1) mediates electroneutral anion
exchange across cell membranes. It is the most abundant protein in the
red cell membrane, but is also found in the basolateral membrane of
renal a-intercalated cells, where it is required for urinary acidification.
Point mutations have been described that convert the red cell AE1 into a
cation conductance. AE1 mutations can also cause hereditary dRTA. I
investigated the properties of four dRTA associated AE1 mutations
(R586H, G609R, S613F and G701D) by heterologous expression in
Xenopus Laevis oocytes. These mutants proved to be functional anion
exchangers, unlike the red cell mutants, but also demonstrated a cation
‘leak’. I found a very large leak property in the G701D mutant, which is
prevalent in SE Asia. I hypothesised that this property might confer a survival advantage. I characterised three other AR dRTA-associated AE1
mutants found in SE Asia, S773P, \Delta850 and A858D via similar transport
experiments in AE1-expressing Xenopus oocytes. These three SE Asian
mutants also had cation leaks of similar magnitude to that seen in
G701D, a property that distinguishes them as a discrete group. The
clustering of these cation-leaky AE1 mutations to malarious areas of SE
Asia suggests that they may confer malaria resistance
Pisma Krzysztofa Kluka jako źródło leksykalne do Słownika języka polskiego S.B. Lindego
No full textThe aim of this paper is to discuss the writings by Krzysztof Kluk (1739–1796), a naturalist of the Enlightenment, the author of Dykcjonarz roślinny (Dictionary of plants) and guidebooks in the fi elds of botany, zoology, and mineralogy as lexical sources of Słownik języka polskiego (Dictionary of Polish) by S.B. Linde (LD). The paper presents an analysis of the material excerpted from Volumes 1 and 3 of LD, which has allowed the estimation that K. Kluk is discussed more frequently in the dictionary than J. Kochanowski, P. Kochanowski, J. Przybylski, and only slightly less frequently than M. Rej and W. Potocki. The material has been analysed also with the use of the method of semantic fields, which has enabled identification of the thematic circles that allow the determination of the angle from which S.B. Linde excerpted vocabulary from K. Kluk’s writings. The lexis from Kluk’s works in LD is not limited only to names of plants, animals or minerals; it covers also parts of the body, animal husbandry (e.g. horses, birds, bee-keeping, fishery), gardening, agriculture, animal diseases, metal and mineral working, transport, construction, home appliances, food, clothes, and social life
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