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    Metode Baru Semi Otomatis Berbasis Active Shape Model Untuk Penentuan Tingkat Keparahan Osteoarthritis Lutut

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    Osteoarthritis (OA) merupakan penyakit arthritis yang sering ditemukan di masyarakat. Beberapa penelitian telah menetapkan bahwa Osteoarthritis (OA) ditemukan pada orang berusia 40-60 tahun dengan prevalensi 15,5% pada pria dan 12,7% pada wanita. Penyakit ini secara bertahap dapat menjadi kronis jika tidak dikontrol secara klinis dengan tepat. Gejala OA ditandai oleh nyeri sendi dan gangguan gerakan karena kerusakan tulang rawan. OA sering terjadi pada persendian lutut, pinggul, tulang belakang, dan kaki. OA dapat terjadi dengan etiologi yang berbeda-beda, namun mengakibatkan kelainan biologis, morfologis dan luaran klinis yang sama. Sehingga, studi mengenai OA dapat dilakukan secara multidisiplin. Identifikasi awal OA memainkan peran penting untuk pengambilan keputusan klinis, mendeteksi keparahan OA dan pengobatan yang tepat. Penyelarasan tulang femur-tibia merupakan faktor risiko utama untuk kejadian dan perkembangan knee osteoarthritis (KOA). Selain itu, untuk menentukan tingkat keparahan OA lutut dapat dilakukan dengan mengklasifikasikan tingkat keparahan berdasarkan KL grade dan Femur Tibia Angle (FTA). Pada penelitian ini, dilakukan penentuan tingkat keparahan OA lutut menggunakan beberapa metode hibrida baru pada citra radiografi (x-ray) yang diperoleh dari Osteoarthritis Initiative (OAI) database. Metode hibrida baru yang dimaksud adalah Structural Two Dimentional Principal Component Analysis (S2DPCA) + Support Vector Machine (SVM) dan Convolutional Neural Network (CNN) + Long Short Term Memory (LSTM) untuk penentuan tingkat keparahan OA lutut berdasarkan KL Grade serta Active Shape Model (ASM) untuk penentuan sudut femur dan tibia (FTA) secara semi otomatis. Hasil ujicoba pada metode S2DPCA + SVM menggunakan 80 citra x-ray lutut dengan ujicoba berdasarkan four-fold cross validation diperoleh hasil maksimal sebesar 94,33% untuk grade 0 dengan kernel Gaussian. Sedangkan untuk metode CNN + LSTM menggunakan 1530 citra x-ray lutut (1055 citra pelatihan dan 475 citra pengujian) dengan ujicoba berdasarkan three-fold cross validation diperoleh hasil maksimal sebesar 75,28% untuk rata-rata dari grade 0 – 4. Sementara itu, untuk metode ASM pada penentuan FTA yang dikembangkan (disebut TRIMA-FTA) dengan menggunakan 60 citra x-ray lutut (10 citra pelatihan dan 50 citra pengujian) diperoleh perbedaan hasil pengukuran antara FTA OAI dan FTA yang cukup kecil, yaitu rata-rata di bawah 0,810 untuk FTA kanan dan di bawah 0,770 untuk FTA kiri. Hasil-hasil tersebut menunjukkan bahwa pendekatan-pendekatan baru yang dikembangkan secara klinis cocok untuk penentuan tingkat keparahan OA lutut berdasarkan KL grade dan pengukuran FTA secara semi otomatis. ================================================================================================================================== Osteoarthritis (OA) is an arthritis diseases that was found commonly in society. Numerous investigations have established that Osteoarthritis (OA) were found in people aged 40-60 years with a prevalence of 15.5% in men and 12.7% in women. This disease gradually became a chronic if not correctly clinical controlled. OA’s symptom is characterized by joint pain and movement disorders due to damage of the cartilage. OA often occurs in the joints of knees, hips, spines and feets. OA can be occur with different etiologies, but the results could be same in biological, morphological and clinical outcomes. Thus, studies on OA can be done in a multidisciplinary science. Early identification of OA plays an important role to improve clinical decision making, to monitor disease progress and appropriate treatment. Some researchers have conducted studies on the severity of knee OA based on Kellgren Lawrence (KL) Grade, Joint Space Width (JSW), osteophyte formation, as well as the angle between the femur bone and the tibia / Femur Tibia Angle (FTA). Furthermore, alignment of the femur-tibia bone is a major risk factor for the occurrence and development of knee osteoarthritis (KOA). In addition, to determine the severity of knee OA can be done by classifying the severity based on KL grade and Femur Tibia Angle (FTA). In this study, the severity of knee OA was determined using several new hybrid methods on radiographic (x-ray) images obtained from the Osteoarthritis Initiative (OAI) database. The new hybrid method is Structural Two Dimentional Principal Component Analysis (S2DPCA) + Support Vector Machine (SVM) and Convolutional Neural Network (CNN) + Long Short Term Memory (LSTM) for determining the severity of knee OA based on KL Grade and Active Shape Model (ASM) for semi-automatic determination of the angle of the femur and tibia (FTA). The results of trials on the S2DPCA + SVM method using 80 knee x-ray images with trials based on four-fold cross validation obtained maximum results of 94.33% for grade 0 with Gaussian kernel. Whereas the CNN + LSTM method uses 1530 knee x ray images (1055 training images and 475 test images) with trials based on three-fold cross validation, the maximum results are 75.28% for an average of grades 0 - 4. Meanwhile , for the ASM method in determining the developed FTA (called TRIMA FTA) using 60 knee x-ray images (10 training images and 50 test images), the difference in measurement results between FTA OAI and FTA is quite small, namely the average in below 0.810 for the right FTA and below 0.770 for the left FTA. These results indicate that new clinically developed approaches are suitable for determining the severity of knee OA based on KL grade and semi-automatic FTA measurements

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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