5,281 research outputs found
Voyage of the Northern Light : newspaper reports and articles.
No full textCover title.; For private circulation only.; Contains typescript copy of a letter from the author to the Daily telegraph.; Library's N copy is inscribed "To the Editor Bulletin, Joshua Slocum ... Strictly private". ANL; Electronic reproduction. Canberra, A.C.T. : National Library of Australia, 2009
Joshua Davis: Author of Spare Parts
No full textCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Obituary of Rev. Joshua C. Wagner, 86, of Jay, a former pastor of several Nazare
No full textObituary of Rev. Joshua C. Wagner, 86, of Jay, a former pastor of several Nazarene churches in Maine
Obituary of Rev. Joshua C. Wagner, 86, of Jay, a former pastor of several Nazare
No full textObituary of Rev. Joshua C. Wagner, 86, of Jay, a former pastor of several Nazarene churches in Maine
The architecture of an empirical genotype-phenotype map
No full textThis DRYAD package contains files from:
Aguilar-Rodríguez, J., Peel, L., Stella, M., Wagner, A., and Payne, J. L. The architecture of an empirical genotype-phenotype map.
This package contains the network files in GML format for the genotype space of transcription factor (TF) binding sites ('genotype_space.gml'), 525 genotype networks of TF binding sites, and 66 genotype networks of DNA binding domains. The genotype networks of TF binding sites are classified in three directories according to their species provenance ('Arabidopsis_thaliana', 'Mus_musculus,' and 'Neurospora_crassa'). Each network file is named with the TF name. More information about these networks can be found in Table S1. The genotype networks of DNA binding domains are within a 'domains' sub-folder that can be found inside each of the three species folders. Each file is named with the DNA binding domain class.
Each network file has the following vertex attributes:
- id: vertex identification number.
- sequence: the nucleotide sequence of the binding site.
- reversecomplement: the reverse complement of 'sequence.'
Genotype network of TF binding sites have the following additional vertex attributes:
- Escore: the enrichment score in protein binding microarrays of the sequence.
- PartitionSBM: Information about the stochastic block model partition group where the vertex is found: '0', '1', or 'None'. 'None' is for vertices not found in the dominant genotype network.
- PartitionBA: Information about the binding affinity partition group where the vertex is found: '0', '1', or 'None'. 'None' is for vertices not found in the dominant genotype network.
For questions regarding these data, contact Joshua Payne at [email protected] or Andreas Wagner at [email protected]
Indigeous author talk
No full textA unique online author event celebrating the diversity of literature created by and for Two-Spirit and Indigiqueer people. This event features writers and creators T’áncháy Redvers and Joshua Whitehead in conversation with host Taya Jardine.Other UBCNon UBCUnreviewedOthe
Data from: The architecture of an empirical genotype-phenotype map
No full textRecent advances in high-throughput technologies are bringing the study of empirical genotype-phenotype (GP) maps to the fore. Here, we use data from protein binding microarrays to study an empirical GP map of transcription factor (TF) binding preferences. In this map, each genotype is a DNA sequence. The phenotype of this DNA sequence is its ability to bind one or more TFs. We study this GP map using genotype networks, in which nodes represent genotypes with the same phenotype, and edges connect nodes if their genotypes differ by a single small mutation. We describe the structure and arrangement of genotype networks within the space of all possible binding sites for 525 TFs from three eukaryotic species encompassing three kingdoms of life (animal, plant, and fungi). We thus provide a high-resolution depiction of the architecture of an empirical GP map. Among a number of findings, we show that these genotype networks are “small-world” and assortative, and that they ubiquitously overlap and interface with one another. We also use polymorphism data from Arabidopsis thaliana to show how genotype network structure influences the evolution of TF binding sites in vivo. We discuss our findings in the context of regulatory evolution.,The architecture of an empirical genotype-phenotype mapThis DRYAD package contains files from: Aguilar-Rodríguez, J., Peel, L., Stella, M., Wagner, A., and Payne, J. L. The architecture of an empirical genotype-phenotype map. This package contains the network files in GML format for the genotype space of transcription factor (TF) binding sites ('genotype_space.gml'), 525 genotype networks of TF binding sites, and 66 genotype networks of DNA binding domains. The genotype networks of TF binding sites are classified in three directories according to their species provenance ('Arabidopsis_thaliana', 'Mus_musculus,' and 'Neurospora_crassa'). Each network file is named with the TF name. More information about these networks can be found in Table S1. The genotype networks of DNA binding domains are within a 'domains' sub-folder that can be found inside each of the three species folders. Each file is named with the DNA binding domain class. Each network file has the following vertex attributes: - id: vertex identification number. - sequence: the nucleotide sequence of the binding site. - reversecomplement: the reverse complement of 'sequence.' Genotype network of TF binding sites have the following additional vertex attributes: - Escore: the enrichment score in protein binding microarrays of the sequence. - PartitionSBM: Information about the stochastic block model partition group where the vertex is found: '0', '1', or 'None'. 'None' is for vertices not found in the dominant genotype network. - PartitionBA: Information about the binding affinity partition group where the vertex is found: '0', '1', or 'None'. 'None' is for vertices not found in the dominant genotype network. For questions regarding these data, contact Joshua Payne at [email protected] or Andreas Wagner at [email protected]</span
Hebrew made easy [electronic resource] : or, a brief introduction to the Hebrew grammar, (upon a new and delightful plan); Whereby our British Gentlemen and Ladies may, in so very short a Time as Twenty-Four Days, learn the most necessary and essential Variations of that incomparable Language, without the Help of the Latin, or the Assistance of a Master. The second edition, with additions. By the author of The great importance of the Hebrew language.
No full textThe author of "The great importance of the Hebrew language" = Joshua Kettilby.Kettilby's 'Hebrew made easy' was first published in [1760?] (c.f.t123545). 'The excellency and great importance of the Hebrew language ... by Joshua Kettilby, author of Hebrew made easy' was published in 1762 (c.f.t183663)Electronic reproduction.English Short Title Catalog,Reproduction of original from Bodleian Library (Oxford)
Reply to Joshua Meltzer
No full textA reply to Joshua Meltzer\u27s comment on the author\u27s paper Bridging Fragmentation and Unity: International Law as a Universe of Inter-Connected Island
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