41,464 research outputs found
Increase in antimicrosomal antibody-related IgG1 and IgG4, and titers of antithyroid peroxidase antibodies, but not antibody dependent cell-mediated cytotoxicity in post-partum thyroiditis with transient hyperthyroidism
To evaluate possible immunological mechanisms involved in the development of postpartum thyroiditis with transient hyperthyroidism followed by transient hypothyroidism (PPT), antithyroid peroxidase antibodies (anti-TPO), antimicrosomal antibody (AMA) related immunoglobin G subclass and antibody-dependent cell-mediated cytotoxicity (ADCC) were studied in 43 post-partum (PP) women who were euthyroid at delivery and completed a subsequent 1 year follow up. Among the 25 mothers who developed PPT, 14 had positive AMA (PPT:AMA+) and 11 negative AMA (PPT:AMA-) at delivery. Among the 18 mothers who remained euthyroid (E) up to one year post-partum and were used as controls, 8 were AMA positive (E:AMA+) and 10 AMA negative (E:AMA-) at delivery. AMA measured by a hemagglutination method correlated well with anti-TPO antibodies measured by RIA in the PP mothers studied. When AMA-related IgG subclass activity was analysed comparing PPT women with appropriate euthyroid controls at the different time intervals studied, it was seen that PPT:AMA+ when compared to E:AMA+ women have significantly increased activity of AMA related IgG1 at all PP time intervals studied (p less than 0.001), but IgG4 was only increased at 5-7 months PP (p less than 0.05). PPT:AMA-when compared to E:AMA- have significantly increased IgG4 at 2-4 (p less than 0.001), 5-7 and 10-12 (p less than 0.05) months PP, but IgG1 is only increased at 5-7 months PP (p less than 0.05)
P Values and Statistical Significance
This resource, created by author Will G. Hopkins, defines what a p-value is, why .05 is significant, and when to use it. It also covers related topics such as one-tailed/two-tailed tests and hypothesis testing. Overall, this is a wonderful resource for students wanting to learn more about statistics, and more specially, significant testing
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A 2 h periodic variation in the low-mass X-ray binary Ser X-1
Spectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1
Linguaggio, simbolo, memoria. Pico e l’ircocervo
This article examines the role of language, symbols, and memory in the thought of Giovanni Pico della Mirandola, focusing on a particular passage in his Apologia where he mentions the "hircocervus". The author explores the meaning of this symbol, linking it to medieval philosophical debates on intelligibility and truth, as well as to the Kabbalistic tradition. By analyzing Pico’s sources a connection emerges between the "hircocervus" and Flavius Mithridates’ translation of the Song of Songs, highlighting the complex interplay between philosophy, Kabbalah, and the art of memory in Renaissance thought. At the same time, this symbol provides a crucial clue for investigating Pico’s mnemonic structures
La construcción de un ethos común en “Don de gentes” de Elvira Lindo. Una interacción a distancia
ABSTRACT
This paper, within the general framework of orality studied in this volume, studies the relation between writing and orality in the press and, more specifically, in editorials. It is also based on recent research that highlighted the presence of orality traits in written press and editorials, as well as in the emerging study of Elvira Lindo’s language and its implications for translation. The analysis includes the presence of thauthor’s self in the statement, as well as the identification of the recipient with whom the author shares opinions and proposes a motivating ethos on various topics with an agile and personal style characterized by humour and irony. At discourse level, the analysis focuses on some of the main features of colloquial syntax, and namely the use conjunctions in discourse function and discourse markers as marks of subjectivity and of the relation with the reader.RESUMEN
En este estudio, enmarcado en el ámbito general de la oralidad del presente volumen, se investiga la relación existente entre escritura y oralidad en el sector de la prensa, y más concretamente en el de la columna de opinión. Se enmarca también en una serie de investigaciones recientes que han evidenciado la presencia de rasgos de oralidad en la prensa escrita y en las columnas de opinión, así como en el todavía incipiente estudio del lenguaje de Elvira Lindo y de sus dificultades de traducción. Se propone para ello el análisis de la presencia del yo del autor en el enunciado, así como la identificación del destinatario con el que comparte una serie de opiniones y propone un motivador ethos sobre diferentes temas con un estilo ágil y personal veteado de humor e ironía. En el plano discursivo se analizan algunos de los rasgos que caracterizan la sintaxis coloquial, para lo que se ha considerado i) el uso de conjunciones en función discursiva; ii) el uso de marcadores discursivos como marcas de la subjetividad y de la relación con el lector
Evidence for erbium-erbium energy migration in erbium(III) bis(perfluoro-p-tolyl)phosphinate
Copyright 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Applied Physics Letters 92, 103303 (2008) and may be found at
William Tarn, Hellenistic Civilisation. Third Edition revised by the Author and G. T. Griffith
Nachtergael Georges. William Tarn, Hellenistic Civilisation. Third Edition revised by the Author and G. T. Griffith. In: L'antiquité classique, Tome 44, fasc. 2, 1975. p. 782
William Tarn, Hellenistic Civilisation. Third Edition revised by the Author and G. T. Griffith
Nachtergael Georges. William Tarn, Hellenistic Civilisation. Third Edition revised by the Author and G. T. Griffith. In: L'antiquité classique, Tome 44, fasc. 2, 1975. p. 782
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