272 research outputs found

    Prof W S Prinsloo and the poetic rendering of the Psalms

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    Continued 2001 as 'Verbum et Ecclesia'Respect and appreciation is paid to Professor W S Prinsloo in this article. He was an exegete who not only opened new theological insights through his approach to the text, but also gave literary guidance. As exegete, he looked at the structure of the Psalms through a literary eye.http://explore.up.ac.za/record=b102527

    Obiit : Professor WiIlem Sterrenberg Prinsloo - 5 October 1997

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    Continued 2001 as 'Verbum et Ecclesia'The death of Professor W S Prinsloo on the 5th of October 1997 had immense consequences. This defecit was an incountable loss for the Old Testament scholarship and science in South Africa. Prinsloo was a competent scholar who had a wide range of international scholarly contacts. He served the Old Testament study with research, lectures and writing. His contribution to the Faculty of Theology at the University of Pretoria cannot be over estimated. In addition to his lecturing responsibilities, his service as dean can be described as monumentous. The Faculty of Theology in particular and the University of Pretoria in general could be grateful for, and proud of this great academic.http://explore.up.ac.za/record=b102527

    Willem Sterrenberg Prinsloo seen from the viewpoint of a colleague

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    Continued 2001 as 'Verbum et Ecclesia'The sudden and tragic death of Professor W S Prinsloo raises many questions that cannot be answered. However, he should be remembered for the huge contribution he has made in the field of Old Testament studies in South Africa. As editor of this journal he was outspoken about the necessity that church and university, theology and science need one another and that theologians are scientific in their research even though it is done from an ecclesiastical viewpoint. As dean he combined strictness with empathy and as a preacher he integrated solid exegesis with spiritual dedication.http://explore.up.ac.za/record=b102527

    Die histories-kritiese metode(s) in perspektief

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    The historical critical method in perspective The historical critical method has made a major contribution to the scientific study of the Bible, especially since the 18th century. The historical critical method, influenced by 19thcentury positivistic and evolusionistic principles of the natural sciences has mainly concentrated on the intention of the original author, the original situation and the growth of the text. The text as it stands has to a large extent been neglected. In reaction to this the text-immanent and structuralistic approaches emerged during the 20th century. The ideal situation would be to combine the three basic elements of the communication process, i.e. the author, the text and the reader in a complementary exegetical model

    Educators' perceptions and practices regarding early literacy instruction and language issues in a Cape Town township primary school

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    Includes bibliographical references (leaves 95-104).This thesis examines the teaching practices and ideas about language and teaching that Foundation Phase educators hold as regard literacy and language issues, and the effect of these ideas and practices on children’s learning. An ethnographic-style case study approach was used to examine classroom-based literacy and language practices. Qualitative classroom-based data indicated a disjuncture between educators' conceptualisations about early learning and their literacy teaching practices and that the teaching practices that were evident did not facilitate successful learning on the part of the learners despite the availability and use of isiXhosa as a medium of instruction. Instead, classroom literacy lessons were limited to rote learning and memorisation, which resulted in learners being passive recipients of literacy knowledge. The study concludes that home language instruction does not of itself guarantee academic success, as learners struggle to learn when are not given the freedom to participate in classroom activities and to become active learners, despite being taught in their home language

    Psalm 97: Almal moet bly wees, want Jahwe is Koning

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    Psalm 97: The Lord is king! Let all the world rejoice. In this article, which was presented as a paper at the congress of South African and Dutch Old Testament Scholars, the author first positions himself methodologically in terms of the South African situation. He then proceeds to use Psalm 97 to illustrate the text-immanent method, the method which he elects to apply. The findings reached are that, although this psalm derives much of its content from the remainder of the Old Testament, it nevertheless forms a coherent whole, and it can be described as an anistic poem in which various techniques of poetry are employed. However, Psalm 97 does not contain a clearly demarcated or even symmetrical strophic division. It is a persuasive text which probably dates from the post-exilic period.  Apparently, the main aim of the psalm was to convince the reader/listener that the Lord is in command

    Stellenbosch University 1st Rugby Team, 1925

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    Donated by Mrs E.C. Keyter.Photomerge created, image cropped.Back row: S. Pretorius, J. Ross, S. Naude, G. Daneel, H. Steyn, W. Louw, J. Pienaar. Middle: G. Brink, J. Prinsloo, G. Pretorius, A.F. Markotter, J. Ie Grange (Capt.), J. de Witt, R. van der Merwe. Front: J. van der Westhuizen, C. Medworth, J. Keyter.Black and white photograph depicting Stellenbosch University's 1st rugby team

    What counts as English? : a discursive investigation between two English language Cape Town primary school grade six classrooms

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    Includes bibliographical references (leaves 63-67).What counts as English depends on the circumstances and where and how it is employed. In classrooms this socio-cultural artefact is constructed through practices in particular ways. Language and literacy practices in schools produce and re-produce certain things that count. In this dissertation I asked what counts as English and what practices were employed in varying contexts to validate what counted in a greater context. I was concerned to find out whether and how English-language resources in different contexts or did not contribute to enhancing students’ (social and economic) mobility. This ethnographically-based study focused on two Grade Six classes in State run Primary schools in Cape Town, one of them being a well-resourced, monolingual, English classroom and school and the other being a poorly-resourced, multilingual, English as an Additional language classroom and school

    Ou Testament Teologie en/of 'Religionsgeschichte'?

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    Old Testament Theology and/or "Religionsgeschichte"This article provides an overview of the latest developments in the area of Old Testament Theology and the relationship thereof to "Religionsgeschichte". The book by Rainer Albertz has played an important role in the debate on the relationship between these disciplines. Attention is given to this debate and particularly to the reaction to the Albertz�s viewpoint as stated at the International Meeting Society of Biblical Literature, Louvain, 7-10 August 1994

    Computational models for conformations of cell wall mycolates from Mycobacterium tuberculosis

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    Dissertation (MSc)--University of Pretoria, 2009.Literature highlights the effects of mycolic acid (MA) fine-structure on biological activity, pathogenicity, virulence and cell wall structure and permeability. Knowledge on MA-structure and how their conformations are dependent on their precise molecular composition becomes essential in exploiting these properties in drug-design and in advancing our understanding of the disease. In our group evidence for a structural or functional relationship between cholesterol and MAs have been discovered. The aim of the experimental part of this work was to study this relationship further by attempting to quantify the interaction between cholesterol and MAs in liposomes on an evanescent field biosensor. The binding profiles that were obtained could not be evaluated with kinetic software and the interaction between cholesterol and MAs was not linearly dependant on the concentration of cholesterol. However, novel insight into the interaction was gained when it was observed that cholesterol only accumulated on MA liposomes when cholesterol liposomes containing concentrations of cholesterol resulting in a suspected liquid ordered phase, were used. This is significant since it implies that cholesterol in membrane rafts of the host cell that exist in a liquid ordered phase would be able to interact with MAs under physiological conditions. The theoretical part of this work represents the first molecular modeling study in which MAs are allowed to fold with no conformational restrictions. It is proposed that MAs fold as a function of their functional groups, stereochemistry, and various chain lengths. It was also investigated whether methylation of the acid group changes conformational preferences. The effect of chain length on cyclopropane structure and the viability of systematic conformational searching in MAs were shown using quantum mechanics. Replicate molecular dynamics simulations were done for 4 ns in vacuo on alpha-; methoxy-; methoxy methyl ester- and keto-MAs. MAs had an open starting conformation without conformational restrictions. Results were analysed using eight distances characteristic of the conformational fold. Using these distances, W-, U- and Z-shaped folds were identified. Principal component analysis (PCA) and self-organising maps (SOMs) were used to evaluate differences and trends in MA-conformations. Quantum chemical results showed that chain length did not affect cyclopropane structure and that the systematic plotting of potential energy surfaces is an effective tool to analyse effects of changes in geometry on the energy of the molecule and to predict favoured conformations. Remarkably, single MAs assumed W-, U- and Z-folds in vacuo during molecular dynamics simulations that have previously been observed in monolayers. PCA and SOM plots showed that keto-MA folded faster than other MAs. Alpha-MA showed the highest frequency of W-, U- and Z-folds. Methoxy-MA did not readily fold at its cis-cyclopropane group. Methylation of the acid group of methoxy-MA did not show remarkable differences in the conformations assumed, but almost doubled the frequency of WUZ-structures obtained as compared to non-esterified methoxy-MA. The inherent structural differences between MA-subclasses clearly affect the trends in structural folds that they assume. Molecular modeling of MAs proved to be a versatile tool for resolving structure-function relationships at the molecular level. Copyright 2008, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. Please cite as follows: Prinsloo, W 2008, Computational models for conformations of cell wall mycolates from Mycobacterium tuberculosis, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd E1400/gmBiochemistryunrestricte
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