1,720,971 research outputs found
Targeting vivax malaria in the Asia Pacific: The Asia Pacific Malaria Elimination Network Vivax Working Group.
Get PDFThe Asia Pacific Malaria Elimination Network (APMEN) is a collaboration of 18 country partners committed to eliminating malaria from within their borders. Over the past 5 years, APMEN has helped to build the knowledge, tools and in-country technical expertise required to attain this goal. At its inaugural meeting in Brisbane in 2009, Plasmodium vivax infections were identified across the region as a common threat to this ambitious programme; the APMEN Vivax Working Group was established to tackle specifically this issue. The Working Group developed a four-stage strategy to identify knowledge gaps, build regional consensus on shared priorities, generate evidence and change practice to optimize malaria elimination activities. This case study describes the issues faced and the solutions found in developing this robust strategic partnership between national programmes and research partners within the Working Group. The success of the approach adopted by the group may facilitate similar applications in other regions seeking to deploy evidence-based policy and practice
Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group
Get PDFThe goal to eliminate malaria from the Asia-Pacific by 2030
will require the safe and widespread delivery of effective
radical cure of malaria. In October 2017, the Asia Pacific
Malaria Elimination Network Vivax Working Group met to discuss
the impediments to primaquine (PQ) radical cure, how these can
be overcome and the methodological difficulties in assessing
clinical effectiveness of radical cure. The salient discussions
of this meeting which involved 110 representatives from 18
partner countries and 21 institutional partner organizations are
reported. Context specific strategies to improve adherence are
needed to increase understanding and awareness of PQ within
affected communities; these must include education and health
promotion programs. Lessons learned from other disease programs
highlight that a package of approaches has the greatest
potential to change patient and prescriber habits, however
optimizing the components of this approach and quantifying their
effectiveness is challenging. In a trial setting, the reactivity
of participants results in patients altering their behaviour and
creates inherent bias. Although bias can be reduced by
integrating data collection into the routine health care and
surveillance systems, this comes at a cost of decreasing the
detection of clinical outcomes. Measuring adherence and the
factors that relate to it, also requires an in-depth
understanding of the context and the underlying sociocultural
logic that supports it. Reaching the elimination goal will
require innovative approaches to improve radical cure for vivax
malaria, as well as the methods to evaluate its effectiveness
Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group
No full textThe goal to eliminate malaria from the Asia-Pacific by 2030
will require the safe and widespread delivery of effective
radical cure of malaria. In October 2017, the Asia Pacific
Malaria Elimination Network Vivax Working Group met to discuss
the impediments to primaquine (PQ) radical cure, how these can
be overcome and the methodological difficulties in assessing
clinical effectiveness of radical cure. The salient discussions
of this meeting which involved 110 representatives from 18
partner countries and 21 institutional partner organizations are
reported. Context specific strategies to improve adherence are
needed to increase understanding and awareness of PQ within
affected communities; these must include education and health
promotion programs. Lessons learned from other disease programs
highlight that a package of approaches has the greatest
potential to change patient and prescriber habits, however
optimizing the components of this approach and quantifying their
effectiveness is challenging. In a trial setting, the reactivity
of participants results in patients altering their behaviour and
creates inherent bias. Although bias can be reduced by
integrating data collection into the routine health care and
surveillance systems, this comes at a cost of decreasing the
detection of clinical outcomes. Measuring adherence and the
factors that relate to it, also requires an in-depth
understanding of the context and the underlying sociocultural
logic that supports it. Reaching the elimination goal will
require innovative approaches to improve radical cure for vivax
malaria, as well as the methods to evaluate its effectiveness
Targeting vivax malaria in the Asia Pacific: The Asia Pacific Malaria Elimination Network Vivax Working Group
Get PDFThe Asia Pacific Malaria Elimination Network (APMEN) is a collaboration of 18 country partners committed to eliminating malaria from within their borders. Over the past 5 years, APMEN has helped to build the knowledge, tools and in-country technical expertise required to attain this goal. At its inaugural meeting in Brisbane in 2009, Plasmodium vivax infections were identified across the region as a common threat to this ambitious programme; the APMEN Vivax Working Group was established to tackle specifically this issue. The Working Group developed a four-stage strategy to identify knowledge gaps, build regional consensus on shared priorities, generate evidence and change practice to optimize malaria elimination activities. This case study describes the issues faced and the solutions found in developing this robust strategic partnership between national programmes and research partners within the Working Group. The success of the approach adopted by the group may facilitate similar applications in other regions seeking to deploy evidence-based policy and practice
Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group.
Get PDFThe goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and the methodological difficulties in assessing clinical effectiveness of radical cure. The salient discussions of this meeting which involved 110 representatives from 18 partner countries and 21 institutional partner organizations are reported. Context specific strategies to improve adherence are needed to increase understanding and awareness of PQ within affected communities; these must include education and health promotion programs. Lessons learned from other disease programs highlight that a package of approaches has the greatest potential to change patient and prescriber habits, however optimizing the components of this approach and quantifying their effectiveness is challenging. In a trial setting, the reactivity of participants results in patients altering their behaviour and creates inherent bias. Although bias can be reduced by integrating data collection into the routine health care and surveillance systems, this comes at a cost of decreasing the detection of clinical outcomes. Measuring adherence and the factors that relate to it, also requires an in-depth understanding of the context and the underlying sociocultural logic that supports it. Reaching the elimination goal will require innovative approaches to improve radical cure for vivax malaria, as well as the methods to evaluate its effectiveness
Quantifying primaquine effectiveness and improving adherence: A round table discussion of the APMEN Vivax Working Group
Get PDFThe goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and the methodological difficulties in assessing clinical effectiveness of radical cure. The salient discussions of this meeting which involved 110 representatives from 18 partner countries and 21 institutional partner organizations are reported. Context specific strategies to improve adherence are needed to increase understanding and awareness of PQ within affected communities; these must include education and health promotion programs. Lessons learned from other disease programs highlight that a package of approaches has the greatest potential to change patient and prescriber habits, however optimizing the components of this approach and quantifying their effectiveness is challenging. In a trial setting, the reactivity of participants results in patients altering their behaviour and creates inherent bias. Although bias can be reduced by integrating data collection into the routine health care and surveillance systems, this comes at a cost of decreasing the detection of clinical outcomes. Measuring adherence and the factors that relate to it, also requires an in-depth understanding of the context and the underlying sociocultural logic that supports it. Reaching the elimination goal will require innovative approaches to improve radical cure for vivax malaria, as well as the methods to evaluate its effectiveness
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: Insights from the 2019 annual APMEN Vivax Working Group meeting
Get PDFAbstract
New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose‐6‐phosphate‐dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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