1,720,996 research outputs found
Left ventricular reverse remodeling prediction in non-ischemic cardiomyopathy: present and perspectives
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How Coronary Perforation Looks at Optical Coherence Tomography Imaging
No full textCoarctation of the aorta is an unusual finding in an adult person during their sixth decade of life. We present a 52-year-old male who presented with left ventricular failure with low ejection fraction and atrial fibrillation who was incidentally detected to have critical coarctation of the aorta, which was successfully managed with balloon angioplasty. The patient had a favorable result at 6 months of clinical follow-up
Hypertrophic restrictive cardiomyopathy with apical thinning: A peculiar case of genotype-phenotype correlation
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Pulmonary artery aneurysm and sarcoidosis
No full textPulmonary artery aneurysm unassociated to congenital heart disease and pulmonary hypertension is exceedingly rare. Its pathogenesis and correct management remain unknown. Sarcoidosis is a systemic disease that can exceptionally involve large vessels, leading to stenosis and dilatation. Pulmonary artery aneurysm has never been described in association with sarcoidosis. Surgical approach should prevent aneurysm rupture, but it is not known when surgery should be preferred to strict medical follow-up. In this report we present a case of large pulmonary artery aneurysm associated to systemic sarcoidosis underlining problematic management of diseases 'forgotten' by evidence based medicine
Bilateral coronary obstruction in high-risk transcatheter aortic valve-in-valve implantation: When procedural strategy counts
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Inquadramento e gestione della pericardite costrittiva: revisione critica
No full textLa pericardite costrittiva è una patologia cronica del pericardio che determina un ostacolo al riempimento delle camere cardiache e scompenso cardiaco. Il quadro clinico è aspecifico e la diagnosi differenziale comprende le malattie del miocardio, in particolare la cardiomiopatia restrittiva. L’iter diagnostico prevede come indagine di primo livello l’ecocardiografia, che rafforza il sospetto diagnostico quando vengano dimostrate alcune anomalie peculiari, quali le accentuate variazioni respiratorie del setto interventricolare e delle velocità di flusso al Doppler transmitralico, tricuspidale e venoso epatico e la normale velocità di rilasciamento protodiastolico al Doppler tissutale. Tali reperti sono espressione dell’accentuata interdipendenza ventricolare e della dissociazione tra le pressioni intratoracica ed intracardiaca tipiche della patologia. L’imaging radiologico (tomografia computerizzata e risonanza magnetica) è utile nel dimostrare la presenza di alterazioni strutturali del pericardio, mentre lo studio emodinamico invasivo è indicato nei casi di incertezza diagnostica e nella valutazione della severità delle alterazioni emodinamiche, specie con potenziali indicazioni chirurgiche. L’intervento di pericardiectomia è indicato nei pazienti sintomatici con diagnosi certa ed è in grado di migliorare i sintomi e la prognosi, anche se gravato da significativa mortalità
Clinical impact of myocardial fibrosis in severe aortic stenosis
Full text linkThe pressure overload due to the progressive narrowing of the valve area determines the development of the left ventricular hypertrophy which characterizes aortic stenosis (AS). The onset of myocardial fibrosis marks the inexorable decline of an initially compensatory response towards heart failure. However, myocardial fibrosis does not yet represent a key element in the prognostic and therapeutic framework of AS. In this context, cardiac magnetic resonance imaging plays a major role by highlighting both the focal irreversible fibrotic replacement, using the late gadolinium enhancement (LGE) technique, and the earlier diffuse reversible interstitial fibrosis, using the T1 mapping techniques. For this reason, the presence of myocardial fibrosis would be useful to identify a subgroup of patients at greater risk of events among the subjects with severe AS. Actually, more and more evidences seem to identify the presence of LGE as a powerful prognostic factor to be used to optimize the timing of prosthetic valve replacement. Randomized clinical trials, such as the EVoLVeD trial currently underway, will be needed to better define the importance of myocardial fibrosis assessment in the management of patients with AS
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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