1,720,961 research outputs found
InstaCircos: A Web Application for Fast and Interactive Circular Visualization of Large Genomic Data (Work in Progress)
No full textOne of the most effective visualizations for genomics data is the circular one, supported by popular packages and visualization suites. Many tools are available, however most of them share a number of negative points including limited ease of installation/usage, slow performance and memory limitations (making them unfeasible for very large genomes such as the human one) and non interactivity. In this paper we present the ongoing work on InstaCircos, a web application born from the scientific collaboration between Big Data Analytics and Bioinformatics researchers and aiming at overcoming the available tools' limitations. It provides advanced visualization features through an easy to use web interface and offers interactive functionalities and near real-Time performances thanks to an integrated big data management back-end based on MongoDB
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Visual Exploratory Data Analysis for Copy Number Variation Studies in Biomedical Research
No full textThe study of Copy Number Variations (CNVs) is recently emerging as a hot topic for biomedical cancer research. While different data sources, websites, and tools concerning genomic CNVs have been made publicly available, CNV data is still a largely unexplored source of biological information, due to the limitations of currently available analysis tools. To this respect, we propose a novel platform, named VarNuCopy, that overcomes such limitations by pursuing the core principles of Exploratory Data Analysis (EDA) in the context of Copy Number Variation (CNV) data. The platform has been made publicly available as a web application, and is, to our best knowledge, the first tool enabling visual, interactive exploration and analysis of the CNV landscape of multiple species. Through novel client and server-side optimizations inspired by scalable data science, VarNuCopy implements a comprehensive and efficient data exploration solution that empowers researchers to easily recognize complex trends and patterns within a huge amount of data concerning CNVs, and to identify new target genes that might function as tumor suppressor and oncogenes
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
VarCopy: A Visual Exploratory Data Analysis Platform for Copy Number Variation Studies
No full textThe study of such a complex phenomenon as cancer, which depends on several but unexplored and unclear factors, needs new ways to visualize, analyze and combine different data both on species characteristics and genes function. To this respect, we propose a novel platform, named VarCopy, supporting visual Exploratory Data Analysis (EDA) in the context of Copy Number Variation (CNV) data. The platform will be publicly available as a web application soon, and is, to our best knowledge, the first tool allowing visual, interactive exploration and analysis of the CNV landscape of multiple species, allowing the identification of new target genes that might be useful for biomedical research
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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