170,225 research outputs found
The role of the counteranion in the cation-pi interaction
No full textChemical double mutant cycles have been used to quantify cation-π interactions in chloroform as a function of the nature of the counteranion. The cation-π interaction is −2.5 ± 0.4 kJ mol−1 and independent of the anion, even though the overall stability of the complexes varies by an order of magnitude due to competition of the anion for alternative binding sites
SENSORIMOTOR DEVELOPMENT IN CEREBRAL-PALSIED INFANTS ASSESSED WITH THE UZGIRIS-HUNT SCALES
No full textSubstituent effects on cation-pi interactions: A quantitative study
No full textA synthetic supramolecular complex has been adapted to quantify cation–π interactions in chloroform by using chemical double-mutant cycles. The interaction of a pyridinium cation with the π-face of an aromatic ring is found to be very sensitive to the π-electron density. Electron-donating substituents lead to a strong attractive interaction (−8 kJ/mol−1), but electron-withdrawing groups lead to a repulsive interaction (+2 kJ/mol−1)
Effet de l'expertise sportive dans le contrôle des mouvements après une pratique intensive dans une tâche de pointage manuel
No full textRobin C., Toussaint L., Blandin Y., Vinter A. Effet de l'expertise sportive dans le contrôle des mouvements après une pratique intensive dans une tâche de pointage manuel. In: Les Cahiers de l'INSEP, n°34, 2003. Expertise et sport de haut niveau. pp. 347-351
Une occasion manquée de préciser la portée de l’arrêt Vinter dans une affaire concernant la France
No full textDans l’arrêt Bodein c. France, la Cour européenne des droits de l’homme applique l’arrêt Vinter en exigeant des peines perpétuelles qu’elles soient compressibles, c’est-à-dire qu’elles prévoient un réexamen. Cependant, elle confirme ce qui était encore incertain dans l’arrêt Vinter : la durée pendant laquelle ce réexamen ne peut pas intervenir reste de la marge d’appréciation des Etats. C’est justement cette marge d’appréciation qui permet à la France d’éviter une condamnation. La Cour européenne manque également l’occasion, dans cet arrêt, de préciser ce qu’elle entend par compressibilité « de facto » qui ne semble pas assortie de véritables conséquences
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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