112 research outputs found

    The Federal Approach to FiscalDecentralisation: Conceptual Contours for Policy Makers

    Get PDF
    Chanchal Kumar Sharma,in his paper demonstrates that in order for fiscal decentralisation to be effective, it must be approached federally. A federal approach is not a decentralised approach but a dynamically balanced approach; one that constantly keeps on adjusting the contrasting forces of centralisation and decentralisation to create a system that can ensure good governance in accordance with the rapidly changing global and local scenario. According to the author, the good governance of the present time has to be federally flexible and dynamically decentralised and institutions of fiscal federalism are crucial for achieving such a dynamic equilibrium. Fiscal decentralisation cannot be detached from the broader principles of fiscal federalism if it is to be successful, irrespective of the fact of whether it is being carried out in a federal or non-federal country. He argues that too much decentralisation or an overly strong central federal government precludes the survival of a constitutional federal state.Federalism; Fiscal Decentralization; centralization

    Nobel Laureate Anthony J Leggett: A scientometric portrait

    Get PDF
    This paper attempts to analyse the publication productivity of Anthony J. Leggett, the 2003 Nobel Prize winner in physics. His contributions peaked in 1987, 1994, and 1998 with 10 papers each. He had 194 publications during 1964 - 2004 in domains like Superfluid 3He (65), Foundations of Quantum Mechanics (36), Dissipative Quantum Systems (24), Atomic Alkali Gases (18), and Miscellaneous (51)which were analysed for authorship pattern with his 70 collaborators. Most active collaborators with Anthony J Leggett were: A. Garg with six papers and A. O. MCaldeira, D. M. Ginsberg, D. J. Vanharlingen , F. Sols, S.Takagi and D. A. Wollman with five papers each. His productivity coefficient was 0.60 which clearly indicates that his productivity increased after 50 percentile age. The highest degree of collaboration (1) for Anthony J. Leggett was found during 1964, 1971 and 1983. Journals have been the most preferred channel of communication, where as many as 139 papers out of 194 have been published. The core journals publishing his papers were: Phys. Rev. Leu. (42), Phys. Rev. B (9), J. Low Temp. Phys. (8),Phys. Rev. A (7), Ann. Phys. (6), Foundations of physics (6), J. Phys.(5), Prog. Theor: Phys. (5), and Rev. Mod. Phys. (5).Publication density was 3.02 and publication concentration was 3.59

    A role for SUMO modification in transcriptional repression and activation

    Get PDF
    Since the discovery of the SUMO (small ubiquitin-related modifier) family of proteins just over a decade ago, a plethora of substrates have been uncovered including many regulators of transcription. Conjugation of SUMO to target proteins has generally been considered as a repressive modification. However, there are now a growing number of examples where SUMOylation has been shown to activate transcription. Here, we discuss whether there is something intrinsically repressive about SUMOylation, or if the outcome of this modification in the context of transcription will prove to be largely substrate-dependent. We highlight some of the technical challenges that will be faced by attempting to answer this question

    Dehydrated Food Waste and Leftover for Trench Composting.

    No full text
    The growing global population has a persistently negative impact on the economy and ecology due to food waste. This topic has recently received much attention from around the world. For both homes and the food processing industry, recycling food waste is crucial to waste management. This study aims to show how dehydrated food scraps and leftovers can be used as raw materials for trench compost to enhance soil quality and reduce leachate and greenhouse gas emissions. The results showed that the pre-treatment and air temperature significantly affected the finished trench compost products’ EC, pH, and nutrient content. Pretreated dried leftover at 80°C after trench compost was found to have the highest value of CNH, S (36.53%), and micronutrients (0.103404%) when compared to micronutrients in the final product of pre-treatment dried leftover at 80℃ after trench compost that was (0.057273%). Dehydrated leftovers from trench compost were thought to have nutrient content that would improve soil quality, slow decomposition, and reduce odor, thus enabling more frequent trash collection

    Biotechnological interventions in food waste treatment for obtaining valuea‘added compounds to combat pollution

    No full text
    Over the last few decades, the globe is facing tremendous effects due to the unnecessary piling of municipal solid waste among which food waste holds a greater portion. This practice not only affects the environment in terms of generating greenhouse gas emissions but when left dumped in landfills will also trigger poverty and malnutrition. This review focuses on the global trend in food waste management strategies involved in the effective utilization of food waste to produce various value-added products in a microbiology aspect, thereby diminishing the negative impacts caused by the unnecessary side effects of non-renewable energy sources. The review also detailed the efficiency of microorganisms in the production of various bio-energies as well. Further, recent attempts to the exploitation of genetically modified microorganisms in producing value-added products were enlisted. This also attempted to address food waste valorization techniques, the combined applications of various processes for an enhanced yield of different compounds, and addressed various challenges. Further, the current challenges involved in various processes and the effective measures to tackle them in the future have been addressed. Thus, the present review has successfully addressed the circular bio-economy in food waste valorization

    Computational Modelling of Pisum Sativum L. Superoxide Dismutase and Prediction of Mutational Variations through in silico Methods

    Get PDF
    Superoxide dismutase (SOD) is one of the major enzymes expressed in the oxidative stress pathway in plants. Its expression is also evident in other taxonomic group in oxidative reactions. Pisum sativum a common plant is being studied in the present work where SOD is characterized using computational tools. SOD sequence of P. sativum [CAA42737.1] Ala and Leu rich protein with alkaline pI value was used as query sequence and used to obtain nine similar sequences through BLASTp. Phylogenetic tree was constructed using MEGA 5.0 based on neighbour joining method. Physiochemical parameters and amino acid composition was studied and compared with query sequences and other similar sequences. Secondary structures were predicted to understand the dominant components. Homology modeling of P. sativum SOD was done using SWISS MODEL and quality was evaluated using standard methods. 27 active sites were detected in SOD predicted model which were Lys rich

    Author response image 1.

    Get PDF
    The field of tissue engineering entered a new era with the development of human pluripotent stem cells (hPSCs), which are capable of unlimited expansion whilst retaining the potential to differentiate into all mature cell populations. However, these cells harbor significant risks, including tumor formation upon transplantation. One way to mitigate this risk is to develop expandable progenitor cell populations with restricted differentiation potential. Here, we used a cellular microarray technology to identify a defined and optimized culture condition that supports the derivation and propagation of a cell population with mesodermal properties. This cell population, referred to as intermediate mesodermal progenitor (IMP) cells, is capable of unlimited expansion, lacks tumor formation potential, and, upon appropriate stimulation, readily acquires properties of a sub-population of kidney cells. Interestingly, IMP cells fail to differentiate into other mesodermally-derived tissues, including blood and heart, suggesting that these cells are restricted to an intermediate mesodermal fate
    corecore