1,728,707 research outputs found
General (Dr) Vijay Kumar Singh (Retd) Minister of State for External Affairs Government of India
No full textVisit by General (Dr) Vijay Kumar Singh (Retd) Minister of State for External Affairs Government of Indi
An approach for traffic situation verification based on spatio-temporal evolution
No full textVijay Kumar Raju MudunuriKlagenfurt, Alpen-Adria-Univ., Master-Arb., 201
TraPS-VarI: Identifying genetic variants altering phosphotyrosine based signalling motifs
Full text linkPatient stratification and individualized therapeutic strategies rely on the established knowledge of genotype-specific molecular and cellular alterations of biological and therapeutic significance. Whilst almost all approved drugs have been developed based on the Reference Sequence protein database (RefSeq), the latest genome sequencing studies establish the substantial prevalence of non-synonymous genetic mutations in the general population, including stop-insertion and frame shift mutations within the coding regions of membrane proteins. While the availability of individual genotypes are becoming increasingly common, the biological and clinical interpretations of mutations among individual genomes is largely lagging behind. Lately, transmembrane proteins of haematopoietic (myeloid and lymphoid) derived immune cells have attracted much attention as important targets for cancer immunotherapies. As such, the signalling properties of haematological transmembrane receptors rely on the membrane-proximal phosphotyrosine based sequence motifs (TBSMs) such as ITAM (immunoreceptor tyrosine-based activation motif), ITIM (immunoreceptor tyrosine-based inhibition motif) and signal transducer and activator of transcription 3 (STAT3)-recruiting YxxQ motifs. However, mutations that alter the coding regions of transmembrane proteins, resulting in either insertion or deletion of crucial signal modulating TBSMs, remains unknown. To conveniently identify individual cell line-specific or patient-specific membrane protein altering mutations, we present the Transmembrane Protein Sequence Variant Identifier (TraPS-VarI). TraPS-VarI is an annotation tool for accurate mapping of the effect of an individual's mutation in the transmembrane protein sequence, and to identify the prevalence of TBSMs. TraPS-VarI is a biologist and clinician-friendly algorithm with a web interface and an associated database browser (https://www.traps-vari.org/)
In Conversation with Vijay Kumar Roy
No full textVijay Kumar Roy (b. 1978) has been recently honoured with Lifetime Achievement Award by Indian Institute of Oriental Heritage, and Poet of the Month in the February 2015 issue of Poets International. He is editor-in-chief of Ars Artium, an international journal of humanities and social sciences (www.arsartium.org) and an honorary member in the editorial boards of a number of international journals in India and abroad. He teaches English at Northern Border University, Arar, Kingdom of Saudi Arabia. He has also taught in two universities in India and one in Ethiopia. Dr Roy writes in English and Hindi. His poems have appeared in a number of national and international journals of repute. His poems have also been anthologised in The Rainbow Hues (2014), The Enchanted World (2013), The Poetic Bliss (2012), The Melodies of Immortality (2012), The Fancy Realm (2011), and Poets’ Paradise (2010). His first book, Premanjali, a collection of poems in Hindi, was published in 2009 and second book, Aesthetic of John Keats: An Indian Approach in 2010. The Melodies of Immortality (2012), an anthology of poetry in English, edited by him, was widely welcomed by leading poets in India. While teaching in Ethiopia he co-translated and edited K. Sekhar’s book Hindi – Speak with the Hearts of Indians (2013), which became very famous and one of the best sellers, particularly in the universities where Indian teachers were teaching and the local teachers aspired to obtain their doctoral degree from Indian universities. Having an avid interest in research, he has edited and published a number of books: Post-Independence Indian Poetry in English: New Experimentation (2015), English Language Teaching: New Approaches and Methods (2013), Spiritual Poetry of India in English Translation (2012), Contemporary Indian Spiritual Poetry in English: Critical Explorations (2012),Teaching of English: New Dimensions (2012), Indian Poetry in English: A Comprehensive Study (2011), Women’s Voice in Indian Fiction in English (2011), and co-edited Comparative Literature: Critical Responses (2014), Contemporary Indian Fiction in English: Critical Studies (2013), Value Education and Professional Ethics: An Anthology (2013),and Humanities and Social Sciences: The Quintessence of Education (2012)
Space-time codes that are approximately universal for the parallel, multi-block and cooperative DDF channels
No full textsj-docx-1-pie-10.1177_09544089221131155 - Supplemental material for Thermo-mechanical and degradation properties of naturally derived biocomposites for prosthesis applications: Analysis of the interface pressure and stress distribution on the developed socket
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221131155 for Thermo-mechanical and degradation properties of naturally derived biocomposites for prosthesis applications: Analysis of the interface pressure and stress distribution on the developed socket by Santosh Kumar, Sumit Bhowmik and Vijay Kumar Mahakur in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
Supplementary_Material__Page_1 – Supplemental material for Circadian Clock Properties and Their Relationships as a Function of Free-Running Period in <i>Drosophila melanogaster</i>
No full textSupplemental material, Supplementary_Material__Page_1 for Circadian Clock Properties and Their Relationships as a Function of Free-Running Period in Drosophila melanogaster by Manishi Srivastava, Vishwanath Varma, Lakshman Abhilash, Vijay Kumar Sharma and Vasu Sheeba in Journal of Biological Rhythms</p
Supplementary_Material__Page_7 – Supplemental material for Circadian Clock Properties and Their Relationships as a Function of Free-Running Period in <i>Drosophila melanogaster</i>
No full textSupplemental material, Supplementary_Material__Page_7 for Circadian Clock Properties and Their Relationships as a Function of Free-Running Period in Drosophila melanogaster by Manishi Srivastava, Vishwanath Varma, Lakshman Abhilash, Vijay Kumar Sharma and Vasu Sheeba in Journal of Biological Rhythms</p
Bilateral Hand Wasting After Coronary Artery Bypass Graft Surgery
No full textJOURNAL OF INVASIVE CARDIOLOGY32375-75United State
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