1,721,123 research outputs found

    Service handbook of the 9.2-inch Howitzer materiel model of 1917 (vickers mark I) and 9.2-inch Howitzer materiel model of 1918 (vickers mark II).

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    CONTENTS List of illustrations VII General description of the 9.2-inch howitzer materiel (Vickers) 1 9.2-inch howitzer, Model 1917 (Vickers) Mark I 5 Howitzer body 5 Breech mechanism 6 Breech closing mechanism 6 Firing mechanism 8 T-Tube type 8 French type (percussion primer) 8 Obturation 12 Nomenclature list 13 9.2-inch howitzer, model 1917 (Vickers) Mark II 16 Howitzer body 16 Breech mechanism 17 Breech closing mechanism 17 Firing mechanism 19 French type firing mechanism (percussion primer) 20 Obturation 21 Nomenclature list 24 9.2-inch howitzers and carriages, Marks I and II (Vickers) 26 Weights and principal dimensions 27 Weights, dimensions, and ballistics 31 Description of the carriage 32 Bed. Carriage body. Cradle. Hydraulic buffer. Instructions for filling the buffer. Recoil control gear for model of 1917 (Vickers Mark I). Recoil control gear for model of 1918 (Vickers Mark II). Recuperation. Instructions for charging the recuperator. Elevating gear. Traversing gear. Traversing indicator. Loading gear. Nomenclature of parts. Tools and accessories 98 Firing beams. Earth box. Air pump. Obturator press. Projectile bearer. Projectile tray. Porter bar. Rammer and sponge. Ground ramps. Picket driver. Recuperator traveling lock. Cradle traveling lock. 9.2-inch howitzer transport wagon (Vickers) 105 Weights and dimensions. Nomenclature of parts. 9.2-inch howitzer carriage transport wagon (Vickers) 129 Weights and dimensions. Nomenclature of parts. 9.2-inch howitzer platform transport wagon (Vickers) 136 Weights and dimensions. Nomenclature of parts. Instructions for operation, care and preservation of the howitzer 142 9.2-inch howitzer, Mark I 142 To dismantle breech mechanism 142 To assemble breech mechanism 142 Care and preservation of howitzer and fittings 142 List of lubricators in breech mechanism 142 9.2-inch howitzer, Mark II 144 To remove breech fittings 144 To assemble breech fittings 145 Care and preservation of howitzer and fittings 145 List of lubricators in breech mechanism 145 Notes 145 Miscellaneous stores 145 Instructions for the care, maintenance, and inspection of the recoil mechanism. 150 Recuperator mechanism. Instructions for care, maintenance, and inspection of the carriage 153 Cradle. Elevating gear. Traversing gear. Cleaning and lubricating. List of lubricating holes. Care and preservation of special accessories. Air pump and driving gear. Care and preservation of howitzer, carriage, and platform transport wagons 156 Rocking bar sight, Mark I. General description 159 Detailed description 163 Gear casing. Sight quadrant. Deflection mechanism. Automatic drift correction gear. Cross leveling mechanism. Sight carrying tube. Range dial operating mechanism. Range dial. Range dial index. Sight operating gear. Identification list for Mark I 169 Rocking bar sight, Mark II 177 Identification list for Mark II 180 Test and adjustment of sighting materiel for 9.2-inch howitzer carriages, Marks I and II 185 To test the range graduation dial. To test the transverse level of the rocking bar sight. To test the longitudinal level. Verification of parallelism of lines of sight and axis of bore 185 Adjustments 186 Additional tests 188 Care and preservation of sight equipment 189 Instructions for assembling the carriage and mounting the howitzer 191 Assembling beams. Assembling bed. Assembling the carriage body. Assembling the howitzer in cradle. Instructions for changing from firing to traveling position. General information 19

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1

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    Inhibitory receptors of the human leukocyte immunoglobulin-like receptor family are constitutively expressed on all myeloid cell types and regulate their functional activity. We demonstrate that ligation of the human leukocyte antigen class I-specific receptor LILRB1, during the differentiation of monocytes to dendritic cells in vitro, results in increased expression of the nuclear factor κB inhibitor protein ABIN1 (also known as TNIP1). Similarly increased expression of ABIN1/TNIP1 was observed in the "immunosuppressive" monocyte populations of patients with non-Hodgkin lymphoma ex vivo. Reducing expression of ABIN1/TNIP1 using small interfering ribonucleic acid allows dendritic cells and immunosuppressive monocytes to respond to stimulation by allowing nuclear factor κB translocation to the nucleus (P &lt; 0.001), increasing cell surface expression of antigen presentation and costimulatory molecules (P &lt; 0.01), increasing phagocytic capacity (P &lt; 0.001), secreting proinflammatory cytokines (P &lt; 0.01), and an increasing ability to stimulate T cell responses (P &lt; 0.05). Our study, therefore, identifies an important functional role for ABIN1/TNIP1 in mediating the effects of LILRB1 ligation-induced inhibitory effects on immune responses. Our findings suggest that inhibiting the LILRB1-ABIN1/TNIP1 pathway in antigen-presenting cells could be a therapeutic approach to stimulate antitumor immune responses. Conversely, stimulation of the pathway may also ameliorate autoimmune diseases in which TNIP1 is a susceptibility gene.</p

    Maternal undernutrition leads to endothelial dysfunction in adult male rat offspring independent of postnatal diet

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    Increasing evidence suggests a role for prenatal environment in the onset of cardiovascular and metabolic disease in later life. In the rat, undernutrition in utero and a postnatal high-fat diet gives rise to a phenotype similar to the metabolic syndrome. As endothelial dysfunction is a feature of both CVD and the metabolic syndrome we investigated the impact of maternal undernutrition and/or postnatal high-fat on endothelial function. Virgin Wistar rats were mated and randomly assigned to groups to receive food either ad libitum (control) or at 30 % of ad libitum intake throughout gestation. At postnatal day 250, a cohort from each group was challenged with a high-fat diet (D12451, 45 % energy from fat; Research Diets, Inc., New Brunswick, NJ, USA) for the remainder of the study. At 1 year of age, small mesenteric arteries were dissected and mounted on a wire myograph and responses to phenylephrine, endothelin, acetylcholine, leptin and sodium nitroprusside assessed. Vasoconstriction to endothelin was significantly enhanced in all groups compared with controls (-log effective concentration equal to 50 % of the maximal response (pEC50); P &lt; 0.001). Endothelium-dependent vasodilatation to acetylcholine was significantly blunted in all groups compared with controls (% maximum response; P &lt; 0.01), while dilatation to leptin and sodium nitroprusside was similar in all groups. These data demonstrate that both maternal undernutrition and postnatal high fat lead to vascular alterations and suggest that maternal undernutrition alone is at least as detrimental to offspring endothelial function as a long-term exposure to a high-fat diet in the offspring<br/

    Leptin reversal of the metabolic phenotype: evidence for the role of developmental plasticity in the development of the metabolic syndrome

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    Events in early life are associated with changes in the risk of disease in later life. There is increasing evidence that these associations are mediated by permanent transcriptional changes in metabolic pathways, in some cases linked to epigenetic alterations. We have proposed that this phenomenon of 'developmental induction' is not a manifestation of pathophysiological processes but rather represents the consequence of developmental decisions made during fetal and early postnatal life to maximize subsequent fitness. However, this fitness advantage is lost if the early and later environments are mismatched. Rats undernourished in utero by maternal underfeeding develop features of the metabolic syndrome, especially if fed on a high-fat diet, but transient neonatal treatment with leptin reverses induction of this adverse metabolic phenotype. This observation demonstrates that developmental programming is reversible and provides strong support for the match-mismatch or predictive model for the origins of developmental programming

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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