1,720,954 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Strukturelle und funktionelle Charakterisierung von Profilin aus Schistosoma japonicum
No full textSchistosomiasis, also known as bilharzia, is considered the second most socio-economically devastating disease after malaria in the (sub)tropical areas. Schistosomiasis is rather effectively treated by praziquantel. However, drug and repeated infections urge the scientific community to search for potent vaccine targets from the Schistosoma proteome. A key to drug and vaccine development is understanding how parasite-‐host recognition works at the molecular level. Neodermatan flatworms contain a unique cellular organ, the syncytial tegument, which plays an important role in host infection. Cytoskeletal proteins form a major fraction of Schistosoma tegumental proteins and are, thus, attractive drug targets. An important cytosolic regulator of actin dynamics in eukaryotes is profilin. In addition to actin, profilins bind to polyproline stretches and acidic phospholipids, which makes them important keys in linking signal transduction to the actin cytoskeleton. This work focused on the biochemical and structural characterization of profilin of Schistosoma japonicum (SjPfn). Profilins
control a complex network of molecular interactions and bind different ligands through poly-‐L-‐proline repeats. Here, the ability of SjPfn to bind octaproline repeats was shown by fluorescence spectroscopy. On the contrary, no binding could be observed for proline-‐rich peptides derived from S. japonicum formin. The crystal structure of SjPfn shows a highly conserved overall fold but also several crucial differences in the peptide binding site compared to canonical profilins. Profilins sequester monomeric actin. This main characteristic of the profilin family was confirmed for SjPfn using polymerization kinetics and cosedimentation assays. Increasing concentrations of SjPfn decrease the rate of actin polymerization by keeping actin in its monomeric, soluble form. The crystal structure of the SjPfn-‐actin complex showed that SjPfn binds actin to the canonical actin-‐binding face, but the binding site itself is remarkably unconserved. The structural and functional information obtained here, provide insight into the profilin-‐ ediated actin dynamics in S. japonicum and clues on the immunogenicity of SjPfn.Schistosomiasis, auch als Billharziose bekannt, ist nach Malaria die sozioökonomisch verheerendste Infektionskrankheit in den (sub)tropischen Regionen. Schistosomiasis kann mit Praziquantel behandelt werden, aber Medikamentenresistenz und wiederkehrende Infektionen erfordern Entwicklung von wirksamen Impfungen gegen die Krankheit. Ein Schlüssel zur Medikamenten-‐ und Impfstoffentwicklung ist das Verständnis, wie die Parasit-‐Wirterkennung auf molekularer Ebene funktioniert. Neodermatan Plattwürmer besitzen ein einzigartiges Zellorgan, das syncytial Tegument, das eine wichtige Rolle bei der Infektion spielt. Zytoskelettproteine formen eine große Fraktion von Schistosoma tegument und sind somit interessante Ziele für Medikamentenentwicklung. Ein wichtiger zytosolischer Regulator der Aktindynamik in Eukaryoten ist Profilin. Außer an Aktin, binden Profiline auch an Polyprolinketten und sauren Phospholipiden, was sie zu wichtigen Schlüsseln zwischen Signaltransduktion und dem Aktinzytoskelett macht. Diese Dissertation befasst sich mit der biochemischen und strukturellen Charakterisierung von Profilin des Schistosoma japonicum (SjPfn). Profiline kontrollieren ein komplexes Netzwerk von molekularen Interaktionen durch Bindung an Liganden mit Poly-‐L-‐Prolinketten. Hier wurde die Fähigkeit zu binden von SjPfn Octaprolinketten gezeigt. Im Gegensatz dazu, konnte keine Bindung von Peptiden von S. japonicum Formin nachgewiesen werden. Die Kristallstruktur von SjPfn zeigt eine hohe Konservierung von der Gesamtstruktur, aber auch wesentliche Unterschiede in der Peptidbindungsstelle im Vergleich zu kanonischen Profilinen. Profilin sequestriert monomeres Aktin. Diese Hauptcharakteristik der Profilinfamilie wurde für SjPfn bestätigt. SjPfn reduziert die Geschwindigkeit der Aktinpolymerisation dadurch, dass es Aktin in seiner monomeren, löslichen Form hält. Die Kristallstruktur des Actin-‐ jPfn-‐Komplex zeigt, dass das SjPfn-‐Aktin an die bekannte Bindungsstelle bindet, aber die Interaktionen bemerkenswert unkonserviert sind. Die strukturellen und funktionellen Informationen geben Einblick in die Profilinvermittelte Aktindynamik in S. japonicum und in Hinweisen auf die Immunogenität von SjPfn
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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