1,720,983 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Vers l'imagerie TEP de la neurotransmission sérotoninergique dans la maladie d'Alzheimer : du radiotraceur au modèle animal.
No full textEarly diagnostic of Alzheimer's disease (AD) is facing difficulties that PET imaging (Positron Emission Tomography) could overcome.The first part of our work was dedicate to the automation and optimization of [11C]PIB synthesis, a radioligand that allows visualizing amyloid load in patients with AD.In a second part, we studied serotoninergic neurotransmission in AD. 5-HT6 receptors antagonists display pro-cognitive properties and post-mortem studies showed their modulation in AD. However, no PET 5-HT6 receptors radioligand is available yet. We report the biological evaluation of [18F]12ST05, a 5-HT6 receptors antagonist radiotracer. A recent clinical PET study using [18F]MPPF (5-HT1A antagonist) demonstrated an increase in 5-HT1A receptors in patients with MCI whereas a decrease could be seen in patients with AD. We could reproduce such a transient up-regulation in a rat model of AD and were able to propose several mechanisms underlying these effects. Our results bring new hypothesis on early stimulated phenomenon in AD and could have potential implication in the therapeutics targeting 5-HT1A receptors.Les difficultés actuelles du diagnostic précoce de la Maladie d'Alzheimer (MA) rendent l'exploration cérébrale par imagerie moléculaire particulièrement pertinente et performante. Les travaux effectués au cours de cette thèse ont développé les méthodologies de l'imagerie TEP (tomographie par émissions de positons) dans cette optique.Une première partie, méthodologique, a consisté à automatiser et à optimiser la radiosynthèse du [11C]PIB, un radiotraceur pouvant détecter l'accumulation des peptides amyloïdes dans le cerveau de patients atteints de la MA. Dans une seconde partie, nous nous sommes intéressés à l'imagerie TEP de la neurotransmission sérotoninergique. Les antagonistes des récepteurs 5-HT6 ont démontré des propriétés procognitives et des études post-mortem ont montrées leur modification dans la MA. Cependant, aucun centre ne dispose encore d'un radiotraceur spécifique. Nous rapportons l'évaluation biologique d'un radiotraceur antagoniste des 5-HT6, le [18F]12ST05. D'autre part, une étude récente en imagerie TEP au [18F]MPPF, un antagoniste des récepteurs 5-HT1A, a révélé une diminution de sa fixation chez des patients Alzheimer alors qu'une augmentation pouvait être constatée chez des patients MCI. Nous sommes parvenus à reproduire une surexpression transitoire des 5-HT1A dans un modèle animal de la MA et nous proposons différents mécanismes compensatoires à l'origine de cette augmentation. Ces résultats apportent des hypothèses sur la nature des phénomènes compensatoires précoces stimulés et pourraient avoir des conséquences sur les thérapeutiques ciblant les 5-HT1A
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Détection de l'Alpha-Synucleine dans le LCS par amplification in vitro (RT-QUIC)
No full textInternational audienc
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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