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DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka
No full textKusuminda, Tharaka, Mannakkara, Amani, Ukuwela, Kanishka D. B., Kruskop, Sergei V., Amarasinghe, Chamara J., Saikia, Uttam, Venugopal, Parvathy, Karunarathna, Mathisha, Gamage, Rajika, Ruedi, Manuel, Csorba, Gábor, Yapa, Wipula B., Patterson, Bruce D. (2022): DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka. Acta Chiropterologica 24 (1): 1-17, DOI: 10.3161/15081109ACC2022.24.1.001, URL: http://dx.doi.org/10.3161/15081109acc2022.24.1.00
FIG. 8 in DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka
No full textFIG. 8. Tragus of Miniopterus species in India and Sri Lanka. A — M. magnater (ZMMU S-172585); B — M. fuliginosus (ZMMU S-164505); C — M. phillipsi sp. nov. (NMSL 2021.03.01.NH, holotype); D — M. pusillus (ZMMU S-172595)Published as part of Kusuminda, Tharaka, Mannakkara, Amani, Ukuwela, Kanishka D. B., Kruskop, Sergei V., Amarasinghe, Chamara J., Saikia, Uttam, Venugopal, Parvathy, Karunarathna, Mathisha, Gamage, Rajika, Ruedi, Manuel, Csorba, Gábor, Yapa, Wipula B. & Patterson, Bruce D., 2022, DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka, pp. 1-17 in Acta Chiropterologica 24 (1) on page 14, DOI: 10.3161/15081109ACC2022.24.1.001, http://zenodo.org/record/773478
FIG. 1 in DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka
No full textFIG. 1. Bayesian majority-rule consensus tree of the COI gene of Asian Miniopterus species. Dark circles depict nodes with Bayesian posterior probability ≥ 0.95 and maximum likelihood bootstrap support ≥ 70. The outgroup Chaerephon plicatus is not shown. Scale bar indicates the number of substitutions per sitePublished as part of Kusuminda, Tharaka, Mannakkara, Amani, Ukuwela, Kanishka D. B., Kruskop, Sergei V., Amarasinghe, Chamara J., Saikia, Uttam, Venugopal, Parvathy, Karunarathna, Mathisha, Gamage, Rajika, Ruedi, Manuel, Csorba, Gábor, Yapa, Wipula B. & Patterson, Bruce D., 2022, DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka, pp. 1-17 in Acta Chiropterologica 24 (1) on page 5, DOI: 10.3161/15081109ACC2022.24.1.001, http://zenodo.org/record/773478
FIG. 6 in DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka
No full textFIG. 6. Lateral aspect of cranium and mandible of Miniopterus species in India and Sri Lanka. A — M. magnater (MHNG 1981.071); B — M. fuliginosus (ZMMU S-164504); C — M. pusillus (V/M/ERS/570); D — M. phillipsi sp. nov. (NMSL 2021.03.01.NH, holotype)Published as part of Kusuminda, Tharaka, Mannakkara, Amani, Ukuwela, Kanishka D. B., Kruskop, Sergei V., Amarasinghe, Chamara J., Saikia, Uttam, Venugopal, Parvathy, Karunarathna, Mathisha, Gamage, Rajika, Ruedi, Manuel, Csorba, Gábor, Yapa, Wipula B. & Patterson, Bruce D., 2022, DNA barcoding and morphological analyses reveal a cryptic species of Miniopterus from India and Sri Lanka, pp. 1-17 in Acta Chiropterologica 24 (1) on page 12, DOI: 10.3161/15081109ACC2022.24.1.001, http://zenodo.org/record/773478
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Identification and characterisation of genetic lesions that predispose to and gene expression patterns that contribute to Myeloid malignancies
Get PDFAcute Myeloid Leukaemia (AML) is a heterogeneous disease caused by multiple genetic lesions. Our laboratory focuses on understanding the genetics of both inherited and acquired haematopoietic malignancies. In this thesis, I have investigated both inherited and acquired genetic changes that contribute to myeloid malignancies. One of the key factors regulating haematopoiesis is GATA2, a zinc finger transcription factor. Germline mutations in GATA2 have been associated with several clinical phenotypes such as myelodysplastic syndrome (MDS)/AML, immunodeficiency disorders (MonoMAC syndrome, DCML deficiency, congenital neutropenia, NK cell deficiency, aplastic anaemia) and Emberger syndrome. Moreover, several somatic mutations in GATA2 have been reported in MDS/AML. Intriguingly, missense somatic and germline mutations reported to date are mutually exclusive, and several clinical phenotypes are associated with specific mutations. We generated a zinc finger 2 (ZF2) mutant allelic series representing a range of clinical phenotypes to investigate how each mutation effects transactivation, DNA binding, protein structure, protein partner interactions and in vitro differentiation. Specific GATA2 mutations perturb the interactions and functions in distinct ways that are beginning to explain differences in observed clinical phenotypes.
We performed gene expression analysis of 91 selected MDS/AML genes, including GATA2, on 166 well annotated primary AML samples, bone marrow mononuclear cells (BMMNC) and CD34 controls. Correlation analyses of GATA2 expression levels with expression of other genes and other mutational and clinical data, was performed to help identify genetic aberrations that cooperate with abnormal levels of GATA2 in AML. Statistical correlations of expression levels of various other genes with outcome and mutation status were also identified. One such correlation was reduced GATA2 expression with oncogenic RAS mutations. A pilot study was carried out to evaluate and optimise an NRAS G12D-induced leukaemia model. All mice transplanted with mutant NRAS G12D rapidly developed haematopoietic disease post-transplantation whereas the control group did not. Based on these pilot studies, we have initiated transplantation experiments in a conditional GATA2 knockout model to investigate the requirement of GATA2 in NRAS G12D induced myeloid disease. Recipient mice continue to be monitored, but are yet to develop disease. We also identified gene expression patterns of prognostic significance in AML and narrowed down a combination of three genes that are highly predictive of outcome. We devised a strategy integrating these genes into currently used risk stratification strategies and significantly improved risk stratification of AML patients at diagnosis. Among syndromes that predispose to MDS/AML, is Diamond Blackfan Anaemia (DBA), a congenital disorder characterised by red blood cell deficiency. The underlying genetic cause of DBA in a child was identified using whole genome sequencing (WGS), targeted massively parallel sequencing (MPS) and high density SNP array. A complex scenario of germline and somatic aberrations were identified in two genetic loci that helped to explain the clinical features seen in the patient and the progression of this disease. These have led to the discovery of a mechanism by which spontaneous remissions occur in DBA patients. Together, these studies have given us valuable insights into malignant myeloid disease biology and offer potential applications in improving therapeutic approaches in AML patients.Thesis (Ph.D.) (Research by Publication) -- University of Adelaide, School of Biological Sciences, 2016
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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