1,969 research outputs found
Architecture for data exchange among partially consistent data models
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2002.Includes bibliographical references (leaves 75-76).by Eswar Venkat Ram Prasad Vemulapalli.S.M
DEA 4580 Course Syllabus - Spring 11
DEA 4580, Introduction to REVIT and Building Information Modeling (BIM), Course Syllabus by Instructor Ramnath Venkat, Spring 201
Fabrication of Integrated Fluidic Systems and Methods to Perform Single-Molecule DNA Analysis.
ABSTRACT
FABRICATION OF INTEGRATED FLUIDIC SYSTEMS AND METHODS TO PERFORM SINGLE-MOLECULE DNA ANALYSIS
by
Venkat Ram Dukkipati
Chair: Stella W. Pang
Stretching DNA from its coiled state into a linear form is an important requirement in DNA-protein interaction studies and DNA sequencing. Immobilization of stretched DNA molecules is required to analyze protein interactions and presence of molecules along the DNA strand. The ability to perform DNA immobilization and stretching in microfabricated fluidic systems is a step towards enhancing the applications of DNA studies. Forces derived from hydrodynamic flow and electric field in channels are used to immobilize and stretch DNA molecules.
Electrodes integrated in fluidic channels are used to stretch DNA molecules using electric field. Fabrication technology for integrating electrodes with Si micro- and nano-channels using polymethylmethacrylate bonding was developed. Bonding is performed at low temperature to form integrated channels without leakage and the channels are hydrophilic, allowing introduction of fluid and biomolecules into the channels by capillary action. A novel DNA immobilization technique called protein assisted DNA immobilization (PADI) was developed to immobilize and stretch hundreds of DNA molecules using hydrodynamic flow in a microchannel. The DNA molecules are not overstretched and the immobilization is performed at physiological pH of 8.0 while maintaining continuous hydration of DNA molecules in the channel. Optical mapping and single-molecule transcription were demonstrated in microchannels using the PADI technique. Precise DNA immobilization and stretching across electrode gaps in microchannels were demonstrated using an ac voltage. Using the ac electric field, large numbers of DNA molecules are immobilized on the electrodes without chemical modifications to the DNA or electrode surface. A mechanism based on induced charge electro-osmosis (ICEO) has been developed to induce motion in suspended particles and move them away from the electrodes. The ICEO induces motion of particles in channels without using fluid flow, unlike dc or ac electro-osmosis, or pressure driven flow. The mechanism is applied to control the motion of DNA molecules in channels using low ac voltage, and a DNA velocity of 24 µm/s has been demonstrated at a distance of 500 µm away from the electrodes.PhDElectrical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/58402/1/dukkipat_1.pd
Network Structure Identification using Corrupt Data-Streams
University of Minnesota Ph.D. dissertation. 2021. Major: Electrical Engineering. Advisors: Andrew Lamperski, Murti Salapaka. 1 computer file (PDF); xii, 137 pages.Many complex systems lend themselves to effective modeling described by a network of dynamically interacting agents. Such modeling is prevalent in many application domains that include climate science, neuroscience, internet-of-things, power grids, and econometrics. The evolution of these systems is governed by the interdependencies and interactions between the agents that can contain feedback loops. Identification of the presence or absence of influence pathways among the agents is of primary importance that enables subsequent analytics in networked systems such as identifying central agents and clusters, devising control strategies in distributed systems, and resource allocation. In most application domains, the nature of the relationships and interdependencies cannot be easily modeled using first principles. Furthermore, in many such systems, it is not possible to deliberately affect the system, and thus passive or noninvasive methods are required. The existing methods of network identification do not account for the common ways through which data gets corrupted. In real-world systems, sensor readings can be inaccurate, clocks can get out of sync, and messages can get lost in transmission over a wireless network. The focus of this research is to incorporate realistic modeling assumptions on data streams and characterize the effects of data corruption on network identification using passive means. We show that identifying the structure of networked systems using corrupt measurements results in the inference of spurious links. The effects of data corruption on network reconstruction are characterized with provable guarantees on the quality of construction with respect to the generative models considered. A wide range of generative models that underlie the data streams are considered that include static interactions (Markov random fields), linear time-invariant dynamical systems, and nonlinear dynamical models. We examine both causal and non-causal inference methods. In both cases, we provide an exact characterization of the location of spurious links. Our results show that the spurious links are localized to the neighborhood of the corrupted node. All our solution methodologies utilize only the time-series observations without any knowledge of the system parameters. Our precise characterization of the erroneous links is further exploited when the network has special structural properties. There are several physical systems, especially flow-driven systems like power grids, heat transfer networks, and fluid flow networks, where every dynamic coupling between the agents/nodes is bi-directional. In such systems, identifying unidirectional links in reconstruction lead to the conclusion that such links arise from data corruption. We utilize our precise characterization of spurious links to detect and localize all corrupt nodes in the network. It is imperative that learning the exact network representation of such systems without spurious links is needed for performing accurate state estimation, control, and optimization. To this, we developed methods to remove all spurious links and identify the exact structure of bi-directed networks despite of data corruption.Subramanian, Venkat Ram. (2021). Network Structure Identification using Corrupt Data-Streams. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/224981
Deformation and Aerodynamic Performance of a Ram-Air Wing
Ram-air wings form an ever increasing market of soft fabric, air inflated wings. They are primairily used in air sports such as parachuting, paragliding and kiting. Ram-air kites may also be used for electric power generation by letting the kite pull a cable from a drum that is connected to a generator. An example if this principle is the Laddermill concept. But since ram-air wings are flexible by nature they will deform and depart from their intended design shape when they are loaded by aerodynamic forces. These deformations generally affect the performance of the wings adversely. Kites with a higher lift-to-drag ratio on the Laddermill could mean a direct increase of the energy produced per square meter of kite. Besides this benefit for the Laddermill there is a huge, world-wide market of parachuting, paragliding and kiting that can benefit from more research and a better understanding of the deformation and aerodynamic performance of ram-air wings. The goals of this thesis are to be able to point out where a ram-air kite departs from the intended design shape, to investigate how well the kite performs, to understand how the deformations affect the airflow and to make suggestions for possible improvements of the design. Since little has been published about these subjects this report will most of all form a basis for further research. This report presents a method to analyse the shape and the aerodynamics of a ram-air kite. The kite is tested in the windtunnel. Its 3D shape is captured using two techniques: photogrammetry and laser scanning. Using the geometry data the structural deformation of the wing is dissected. With computational fluid dynamics the aerodynamics of the deformed shape is analyzed. An extra result of this study is the comparison of photogrammetry and laser scanning in terms of their suitability to capture the 3D shape of the ram-air kite. A number of interesting deformations and flow features were found on the ram-air wing: - Theoretically the bumps (ballooning) and grooves on a ram-air wing hinder the spanwise flow on a 3-dimensional wing, but in practise this effect is only visible on small parts of the upper surface. - The pull of the suspension lines on the under surface and the internal construction of the wing make the upper surface of the wing deform. This results in a decrease of the upper surface curvature, especially near the nose. This curvature decrease causes a loss of lift of at least 5%. - Because the flat, 2-dimensional fabric is inflated into a 3-dimensional shape the fabric wrinkles. The wrinkles continue from the top and bottom surface into the ribs that internally connect and support the top and bottom surface. On average these wrinkles shorten the ribs in chordwise direction by 3.5%. This decreases the surface area of the wing and it makes the ribs effectively thicker. Many more details became visible with the thorough analysis of the wing’s shape. The conclusion is that the performance of the ram-air wing can be improved by changing these details. The photogrammetry measuring technique gave better results than laser scanning and is very suitable tool to make these details visible. It allows a designer to identify where the real flying shape deviates from the design shape. This can help kite designers and designers of other ram-air wings to reverse-Aerospace Engineerin
Great Expectatrics: Great Papers, Great Journals, Great Econometrics
The paper discusses alternative Research Assessment Measures (RAM), with an emphasis on the Thomson Reuters ISI Web of Science database (hereafter ISI). The various ISI RAM that are calculated annually or updated daily are defined and analysed, including the classic 2-year impact factor (2YIF), 5-year impact factor (5YIF), Immediacy (or zero-year impact factor (0YIF)), Eigenfactor score, Article Influence, C3PO (Citation Performance Per Paper Online), h-index, Zinfluence, and PI-BETA (Papers Ignored - By Even The Authors). The ISI RAM data are analysed for 8 leading econometrics journals and 4 leading statistics journals. The application to econometrics can be used as a template for other areas in economics, for other scientific disciplines, and as a benchmark for newer journals in a range of disciplines. In addition to evaluating high quality research in leading econometrics journals, the paper also compares econometrics and statistics, alternative RAM, highlights the similarities and differences in alternative RAM criteria, finds that several ISI RAM capture similar performance characteristics for the leading econometrics and statistics journals while the new PI-BETA criterion is not highly correlated with any of the other ISI RAM, and hence conveys additional information regarding ISI RAM, highlights major research areas in leading journals in econometrics, and discusses some likely future uses of RAM.Research assessment measures, impact factors, Immediacy, Eigenfactor score, Article influence, h-index, C3PO, Zinfluence, PI-BETA
Scientometric portrait of Ram Gopal Rastogi
Publication productivity of Indian scientist (R.G. Rastogi) has been documented.
Scientometric analysis of 312 papers by Ram Gopal Rastogi published during 1954 to 1992 in various domains: (a) Luni -solar activity and quiet -time E & F- region (57); (b) Equatorial electric field and low and mid latitude iof:osphere (78); (c) Ionospheric E- region irregularities (19); (dj Ionospheric F- region irregularities (32); and (e) Magnetic disturbance effects on the equatorial low and mid latitude ionosphere (23) were analysed. Interdomainery contents and of the number of papers: a+b were 36; b+c and b+d were 20 each; b+e were 16;. c+e were 5; a+e were 3; d+e were 2; and a+d had only one publication. Highest collaborations were with H. Chandra (61), M.R. Deshpande (42), and G. Sethia (19) out of his total 97 collaborators. His highest productivity was during 1978 with 28 papers followed by 19 papers during 1977. The core journals preferred by him for publishing papers were: Indian Journal of Radio & Space Physics, India, and Journal of Atomic & Terrestrial Physics, UK (59 each), followed by Proceedings of the Indian Academy of Sciences, India (34). Most prolific title keywords with their frequencies were: Ionosphere (92); Equatorial (61); F-region (53); Equatorial electrojet region (40), and Magnetic equator (30)
Great Expectatrics: Great Papers, Great Journals, Great Econometrics
The paper discusses alternative Research Assessment Measures (RAM), with an emphasis on the Thomson Reuters ISI Web of Science database (hereafter ISI). The various ISI RAM that are calculated annually or updated daily are defined and analysed, including the classic 2-year impact factor (2YIF), 5-year impact factor (5YIF), Immediacy (or zero-year impact factor (0YIF)), Eigenfactor score, Article Influence, C3PO (Citation Performance Per Paper Online), h-index, Zinfluence, and PI-BETA (Papers Ignored - By Even The Authors). The ISI RAM data are analysed for 8 leading econometrics journals and 4 leading statistics journals. The application to econometrics can be used as a template for other areas in economics, for other scientific disciplines, and as a benchmark for newer journals in a range of disciplines. In addition to evaluating high quality research in leading econometrics journals, the paper also compares econometrics and statistics, alternative RAM, highlights the similarities and differences in alternative RAM criteria, finds that several ISI RAM capture similar performance characteristics for the leading econometrics and statistics journals while the new PI-BETA criterion is not highly correlated with any of the other ISI RAM, and hence conveys additional information regarding ISI RAM, highlights major research areas in leading journals in econometrics, and discusses some likely future uses of RAM.Research assessment measures; impact factors; Immediacy; Eigenfactor score; Article influence; h-index; C3PO; Zinfluence; PI-BETA
Steady-State Solver for a Ram-Air Kite Aeroelastic Model Based on Dynamic Relaxation
We present a computationally efficient steady-state solution method to model the aeroelastic deformation of a ram-air kite for airborne wind energy applications. The kite’s weight in comparison to the aerodynamic forces is small which justifies a quasi-steady analysis, neglecting gravitational and inertial force effects [1]. The approach is suitable to efficiently determine the deformed configuration of a ram-air kite for design and optimization purposes as found in [2]. Because of the expected large deformations and changes in the flow field, fluid-structure interaction has to be taken into account in the analysis.Wind Energ
Night-Time Stories from The Panchatantra
Similar to Arora's 101 Moral Stories of Grandpa, this hardbound book with dust-jacket has 100 pages. The T of C on 6 lists fifteen numbered stories. This book is remarkable for offering a large picture on almost every page. New to me is The Sparrows & the Tusker (51). An elephant breaks off a limb and unwittingly destroys a nest. The sparrows get help from a woodpecker, a fly, and a frog, Together they lull the elephant, blind him by pecking out his eyes, and mislead him into a deep pit he mistakes for a water-hole. It is nice to meet old friends from the Panchatantra and Kalila and Dimna tradition, and I enjoy Ram-Lakshman's art. One of the best images here is that of the lion springing into the well as the hare runs away (99). The dust-jacket is glued to the covers.This is a hardbound book (hard cover)This book has a dust jacket (book cover)Retold by Reinu Bhano
- …
