186,699 research outputs found
Bronchial reactivity in asthmatic children at high and low altitude. Effect of budesonide
No full textInhaled steroids may control bronchial inflammation in asthmatics exposed to allergens. In this study we evaluated whether prophylactic budesonide would prevent relapse of asthma in children re-exposed to offending allergens at sea level, after a period of antigen avoidance at high altitude. Thirty children received either budesonide (200 micrograms b.i.d.) or placebo (double-blind). Following a 4-wk baseline period and 2 wk of treatment at high altitude, children were treated for 3 mo at sea level. Methacholine challenge and pulmonary function studies were performed before and after baseline period, after the 2 wk of treatment in the mountain environment, and at the end of treatment. ECP serum levels were evaluated after the baseline period and at the end of treatment. PEFR and symptoms were recorded in a diary card during the study. The increase in methacholine provocative dosage was greater, although not significant (p = 0.096), in the budesonide than in the placebo group after the treatment at high altitude and remained higher at the end of the treatment (p = 0.04). ECP levels increased in both the groups with no significant difference. Our results confirm that budesonide, in addition to its efficacy in treating pre-existent airway inflammation, is effective in preventing the increase of reactivity in asthmatic children re-exposed to allergens
Effect of natural allergen avoidance on heath-labile chemotactic activities for eosinophils (HL-ECA) and eosinophil protein X (EPX) in allergic children
No full textEffect of natural allergen avoidance on heath-labile chemotactic activities for eosinophils (HL-ECA) and eosinophil protein X (EPX) in allergic childre
Effects of high altitude on eosinophil cationic protein serum levels in asthmatic allergic children
No full textExperimental study on the effect of high altitude on airway inflammatio
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Eosinophils and serum eosinophilic cationic proteins in interleukin-2- based immunotherapy for cancer [3]
No full textNO ABSTRAC
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Effects of antigen avoidance in high altitude on eosinophil cationic protein (ECP), eosinophil protein X (EPX) and specific IgE for dermatophagoides pteronyssinus (Dpt) serum levels in asthmatic children
No full textStudy on the effects of antigen avoidance in high altitude on eosinophil cationic protein (ECP), eosinophil protein X (EPX) and specific IgE for dermatophagoides pteronyssinus (Dpt) serum levels in asthmatic childre
Influence of allergen avoidance at high altitude on serum markers of eosinophil activation in children with allergic asthma.
No full textA cohort of 12 asthmatic children was followed over several months, during which
they moved back and forth from an allergen-free to an allergen-rich environment
at high and low altitude, respectively. The children were treated with
non-steroidal anti-asthmatic drugs as clinically needed. Histamine PC20-FEV1 was
unaltered during the study period, whereas serum levels of eosinophil cationic
protein (ECP) and eosinophil protein X (EPX) showed significant changes when the
children were exposed to the offending allergens. The total IgE significantly
increased during exposure. The serum levels of myeloperoxidase (MPO) as well as
of chemotactic factors for both neutrophils and eosinophils were unaltered during
allergen exposure. We conclude that the serum markers of eosinophil activity ECP
and EPX are sensitive indices of allergen exposure in asthmatic atopic children
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