1,720,971 research outputs found
Focus Farmacovigilanza: il nuovo sistema di informazione dei centri regionali di Farmacovigilanza
No full textL'abstract presenta Focus Farmacovigilanza, il bollettino interregionale di Farmacovigilanza
Anti-inflammatory activity of monomethoxypolyethylene glycol superoxide dismutase on adjuvant arthritis in rats.
No full textIn previous studies we observed an enhanced anti-inflammatoryactivity of MPEG-SOD derivatives in acute inflammation in rat.
To assess the activity in chronic inflammation we tested the compound with longer half-life (MPEG-SOD 18) in complete adjuvantarthritis in rat. According to the prophylactic schedule of treatment (i.m. administration at alternative days of 10 mg/kg from day 3 to day 21), the MPEG-SOD derivative reduced arthritic lesions in a significant way (P<0.01 at 14th, 21st, 28th day).
Indomethacin, administered i.m. daily at the dose of 1.5 mg/kg according to the same schedule, significantly inhibited adjuvantarthritis each time it was considered (% of inhibition are 66.5% at 14th day, 58.3% at 21st day and 50.8% at 28th day).
Native SOD and inactivated enzyme, administered from day 3 to day 21 did not show any anti-inflammatory properties.
According to the therapeutic schedule of treatment (from day 14 to day 28), neither MPEG-SOD nor native SOD showed antiarthritic activit
Anti-inflammatory and pharmacokinetic properties of superoxide dismutase derivatized with polyethylene glycol via active esters.
No full textIntestinal bacterial flora and lesions in arthritic rats: effect of antiinflammatory drug.
No full textIntestinal bacterial flora and lesions in arthritic rats: effect of antiinflammatory drug
Are bacterial toxins involved in arthritis induced in rats?
No full textEvaluation of bacterial toxinsto establish their involvement in arthritis induced in rat
Acute hepatitis caused by green tea infusion: a case report .
No full textThe consumption of tea originated in Asia thousands of years ago and was introduced progressively all around the world. In the literature there are some reports of adverse hepatic reaction associated to green tea. We describe and discuss a case of acute hepatitis caused by the use of green tea infusion
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
PEG superoxide dismutase derivatives: anti-inflammatory activity in carrageenan pelurisy in rats.
No full text- …
