1,721,456 research outputs found

    Vector Biology Boot Camp Toolkit

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    The Vector Biology Boot Camp is a program offered by the Northeast Regional Center for Excellence in Vector-Borne Diseases to provide hands-on learning opportunities in vector surveillance and control program operations. The program is designed for vector-borne disease professionals working in the Northeast region of the United States and covers tick and mosquito species of medical importance to this region. The program was initially developed by Laura Harrington, Emily Mader, and NEVBD colleagues, and was first hosted in 2018. The program has been held on an annual basis since this time, excluding calendar year 2022. The purpose of this toolkit is to share operational details of the Vector Biology Boot Camp with others, with the intention to support those who may start a similar program. Examples of learning outcomes, materials and supplies, and evaluation instruments are provided in this guide.This work was supported by the Centers for Disease Control and Prevention (awards U01CK000509 and U50CK000633). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Centers for Disease Control and Prevention

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Vector Biology Boot Camp: Workplace Impact Assessment from Program Attendees

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    The Vector Biology Boot Camp is an annual event offered by the Northeast Regional Center for Excellence in Vector-Borne Diseases (NEVBD) and the Louis Calder Center of Fordham University, providing hands-on learning opportunities in vector surveillance program operations. The program is designed for vector-borne disease professionals working in the Northeast, covering tick and mosquito species of medical importance to this region. This report provides a summary of the impact of program attendance on workplace operations for attendees to the 2018 and 2019 Vector Biology Boot Camp.Northeast Regional Center for Excellence in Vector-borne Diseases is supported through Cooperative Agreement Number 1U01CK000509-01 between the Centers for Disease Control and Prevention (CDC) and Cornell Universit

    Dataset for 'Unpacking WHO and CDC Bottle Bioassay Methods: A Comprehensive Literature Review and Protocol Analysis Revealing Key Outcome Predictors'

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    Repository for the data and r scripts used to analyse data in "Unpacking WHO and CDC Bottle Bioassay Methods: A Comprehensive Literature Review and Protocol Analysis Revealing Key Outcome Predictors" Murphy et al 2024

    Dataset for the article: Mechanistic modelling of within-mosquito viral dynamics: Insights into infection and dissemination patterns

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    Modelling within mosquito virus dynamics and links to vector competence experiments All code to produce figures is available here: https://github.com/jenniesuz/within_mosquito_virus_dynamics

    Data from: Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

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    It is currently unknown whether all Plasmodium falciparum infected mosquitoes are equally infectious. We assessed sporogonic development using cultured gametocytes in the Netherlands and naturally circulating strains in Burkina Faso. We quantified the number of sporozoites expelled into artificial skin in relation to intact oocysts, ruptured oocysts, and residual salivary gland sporozoites. Sporozoites were quantified by highly sensitive qPCR; intact and ruptured oocysts by fluorescence microscopy following antibody staining of circumsporozoite protein. In laboratory conditions, higher total sporozoite burden in mosquitoes was associated with a shorter duration of sporogony (p<0.001). Overall, 53% (116/216) of P. falciparum infected An. stephensi mosquitoes expelled sporozoites into artificial skin. The medians of expelled and residual salivary gland sporozoites were 136 (IQR: 34-501) and 23,947 (IQR: 9127-78,380), respectively. There was a strong positive correlation between ruptured oocyst number and salivary gland sporozoite load (ρ=0.8; p<0.0001) and a weaker positive correlation between salivary gland sporozoite load and the number of sporozoites expelled (ρ=0.35; p=0.0002). In Burkina Faso, An. coluzzii mosquitoes were infected by natural gametocyte carriers. Among mosquitoes that were salivary gland sporozoite positive, 89% (33/37) expelled sporozoites with a median of 1035 expelled sporozoites (IQR: 171-2969) and harbored a median of 45,100 residual salivary gland sporozoites (IQR: 20,310-164,900). Again, we observed a strong correlation between ruptured oocyst number and salivary gland sporozoite load (ρ=0.9; p<0.0001) and a positive correlation between salivary gland sporozoite load and the number of sporozoites expelled (ρ=0.7; p<0.0001). Mosquito salivary glands in Burkina Faso harbored 1-3 distinct parasite clones; several mosquitoes expelled multiple parasite clones during probing.Whilst sporozoite expelling was regularly observed from mosquitoes with low infection burdens, our findings indicate that mosquito infection burden is associated with the number of expelled sporozoites. Future work is required to determine the direct implications of these findings for transmission potential

    Data for 'Small dams drive Anopheles abundance during the dry season in a high malaria burden area of Malawi'

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    Household-level CDC Light Trap data for three communities in Kasungu, May - August 202
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