1,720,971 research outputs found

    Migraine: a disorder of brain excitatory-inhibitory balance?

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    Migraine is a common disabling brain disorder whose key manifestations are recurrent attacks of unilateral headache and interictal hypersensitivity to sensory stimuli. Migraine arises from a primary brain dysfunction that leads to episodic activation and sensitization of the trigeminovascular pain pathway and as a consequence to headache. Major open issues concern the molecular and cellular mechanisms of the primary brain dysfunction(s) and of migraine pain. We review here our current understanding of these mechanisms, focusing on recent advances regarding migraine genetics, headache mechanisms, and the primary brain dysfunction(s) underlying migraine onset and susceptibility to cortical spreading depression, the neurophysiological correlate of migraine aura. We also discuss insights obtained from the functional analysis of familial hemiplegic migraine mouse models

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    ‘De fugiendis coreis’: l'organizzazione duecentesca di una serie di racconti edificanti

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    Prima di divenire l'oggetto di un dibattito più articolato nell'età della Riforma, la danza figura, fra tredicesimo e quindicesimo secolo, fra i bersagli più frequenti e caratteristici della censura monastico-clericale nei confronti degli interessi e delle occupazioni mondane. La circolazione nella cultura scritta del basso Medioevo di un insieme di argomentazioni volte a sostenere questa condanna, e destinate a un uso privilegiato nella sfera della predicazione, tende ad assumere, all'interno della manualistica religiosa del tempo, la forma strutturata di capitoli più o meno ampi specificamente dedicati al tema dei balli, e trova, nel genere narrativo dell'exemplum, una delle sue forme più fortunate. Una ricostruzione di questa tradizione edificante, rimasta nel suo episodio fondamentale manoscritta, può tornare utile per stabilire l'immagine della danza (e in qualche misura, in rapporto ad essa, quella della musica) che viene elaborata all'interno dell'ambiente culturale del cristianesimo dell'Occidente medievale, e di lì proiettata sui destinatari di tale produzione letteraria. Quanto ci si propone in questo contributo è l'esame del capitolo riservato a questo argomento all'interno di un trattato fra i più influenti in questo settore. La sistemazone che vi è proposta per il tema della danza potrà servire da specchio di un complesso di atteggiamenti e di pratiche discorsive dalle dimensioni più ampie e di lunga durata

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    BANDAGGIO ORTODONTICO: STUDIO COMPARATIVO TRA UN CEMENTO VETROIONOMERICO RESINARINFORZATO ED UN CEMENTO COMPOSITO TRADIZIONALE PASTA-PASTA

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    Scopo del presente lavoro è stato quello di valutare e confrontare le caratteristiche di adesività di un cemento vetroionomerico fotopolimerizzante resina-rinforzato, usato per il bonding diretto dei bracket, e di un a resina composita chimico-polimerizzante due-paste tradizionale. A tal fine è stata confrontata sperimentalmente la forza di distacco al taglio dei brackets adesi con i due materiali in studio
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