169,816 research outputs found
Aspects of health economics in the treatment of pain and sleep deficit
No full textVauth C, Greiner W. Aspects of health economics in the treatment of pain and sleep deficit. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT. 2009;134(S 04):S144-S147
Medical and Cost Effectiveness of Bariatric Surgery in Obesity. Results of an HTA Commissioned by the German Agency for Health Technology Assessment
No full textVauth C, Stoeber Y, Bockelbrink A, Greiner W. Medical and Cost Effectiveness of Bariatric Surgery in Obesity. Results of an HTA Commissioned by the German Agency for Health Technology Assessment. In: Value in Health. Value in Health. Vol 11. Elsevier BV; 2008: A634-A635
Growth of vapor-deposited amorphous Zr65Al7.5Cu27.5 films under oblique particle incidence investigated by experiment and simulation
No full textAmorphous thin film growth is of high scientific interest due to the possibility of identifying growth processes without the superposition of anisotropies. Oblique particle incidence offers the exciting possibility of breaking this isotropy in the plane of the substrate and of creating nanostructure films dependent on the tilt angle, which enters as an additional parameter. We investigate this structure formation and the nature of the underlying atomic-scale processes with experiments and computer simulations. This is achieved by a detailed film characterization using scanning tunneling microscopy and transmission electron microscopy and a numerical analysis of the data as well as with Monte Carlo and continuum growth models. Measures such as rms roughness or spectral power density are utilized for a quantitative characterization and comparison of experiment and theory. This allows us to identify surface diffusion, shadowing, and steering as the main ingredients for oblique film growth
Atomic dynamics in molecular dynamics simulations of glassy CuTi thin films
No full textWe present results on atomic dynamics in metallic glass thin films below the glass transition temperature using molecular dynamics simulations. Thin CuTi films of different compositions are prepared by quenching the liquid to an amorphous state. The atomic dynamics on the amorphous surface and inside the bulk of the samples are quantitatively compared by calculating diffusion constants and jump length distributions. Here, we focus on the collective or single particle character of the diffusion mechanism in dependence of the atom type. In addition, single atom exemplifications are analyzed for the different kinds of atomic dynamics. We find that Cu surface atoms diffuse with a single atom jump dynamics, whereas inside the bulk collective behavior dominates for both species. (C) 2005 American Institute of Physics
Clinical outcome and cost-effectiveness of different bypass materials in vascular surgery
No full textEidt D, Roll S, Vauth C, Greiner W, Willich SN, Von der Schulenburg J. Clinical outcome and cost-effectiveness of different bypass materials in vascular surgery. In: Value in Health. VALUE IN HEALTH. Vol 8. BLACKWELL PUBLISHING; 2005: A114
Scientific guidelines and their implementation in health policy
No full textvon der Schulenburg J-MG, Mittendorf T, Vauth C, Greiner W. Scientific guidelines and their implementation in health policy. VALUE IN HEALTH. 2008;11(4):547-548
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Nursing concepts for patients with dementia
No full textNocon M, Roll S, Schwarzbach C, Vauth C, Greiner W, Willich SN. Nursing concepts for patients with dementia. ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE. 2010;43(3):183-189.Today there are approximately one million people with dementia in Germany. Because most forms of dementia cannot be cured the focus of treatment is to provide adequate care, aiming at the maintenance of cognitive functioning, the ability to perform everyday tasks and quality of life. Important approaches for dementia care are multisensory stimulation, validation, reality orientation and reminiscence therapy. However, the efficacy of these approaches is unclear. A systematic review of the literature was performed. We included randomised controlled trials with at least 30 participants on the efficacy of multi-sensory stimulation, validation, reality orientation and reminiscence therapy for dementia. No restrictions were defined with regard to the endpoints under investigation. A total of 14 studies with 1,513 patients could be included of which 5 studies assessed reminiscence therapy, 4 multi-sensory stimulation, 3 validation and 2 reality orientation. The studies analysed cognitive functioning, behavioural outcomes, psychological symptoms and quality of life. Most studies did not find significant differences between the intervention and the control group. The studies conducted to date provide only little evidence for the efficacy of the approaches for dementia care considered in this review. However, only few methodologically robust studies could be identified for this review which highlights the need for more interventional studies
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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