263,111 research outputs found

    Varley, Joanna, October 8, 2009 [Interview]

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    Joanna Varley was interviewed on October 8, 2009, by John Thomas Varley about her experiences on the home front during World War II.World War I

    Geophysical characterization of hydrothermal systems and intrusive bodies, El Chichón volcano (Mexico)

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    [1] The 1982 explosive eruptions of El Chichón volcano (Chiapas, Mexico) destroyed the inner dome and created a 1-km-wide and 180-m-deep crater within the somma crater. A shallow hydrothermal system was exposed to the surface of the new crater floor and is characterized by an acid crater lake, a geyser-like Cl-rich spring (soap pool), and numerous fumarole fields. Multiple geophysical surveys were performed to define the internal structure of the volcanic edifice and its hydrothermal system. We carried out a high-resolution ground-based geomagnetic survey in the 1982 crater and its surroundings and 38 very low frequency (VLF) transects around the crater lake. A 3-D inversion of the ground-based magnetic data set highlighted three high-susceptibility isosurfaces, interpreted as highly magnetized bodies beneath the 1982 crater floor. Inversion of a digitized regional aeromagnetic map highlighted four major deeply rooted cryptodomes, corresponding to major topographic highs and massive lava dome outcrops outside and on the somma rim. The intracrater magnetic bodies correspond closely to the active hydrothermal vents and their modeled maximum basal depth matches the elevation of the springs on the flanks of the volcano. Position, dip, and vertical extent of active and extinct hydrothermal vents identified by VLF-EM surveys match the magnetic data set. We interpret the shallow lake spring hydrothermal system to be mostly associated with buried remnants of the 550 BP dome, but the Cl-rich soap pool may be connected to a small intrusion emplaced at shallow depth during the 1982 eruption

    Improved Prognostic Testing for Patients with Triple Negative Breast Cancer

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    Approximately 40% of patients with stage I-III triple-negative breast cancer (TNBC) have recurrences after standard treatment, whereas the remaining 60% experience long-term disease-free survival. However, there are currently no clinical tests to assess the risk of recurrence in TNBC patients. To address this issue, Varley and colleagues developed a multigene MHCII Immune Activation Assay to allow clinical testing for the prognosis of recurrence of triple-negative breast cancer patients. This assay identifies TNBC patients with a low risk of recurrence whose tumors express factors like MHC II pathway components, which promote immune infiltration and responses that reduce relapse and enhance survival. This work addressed a critical need for prognostic biomarker tests that enable precision medicine for TNBC patients

    Understanding the effect of nanomodifier addition upon the properties of fibre reinforced laminates

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    This work presents a survey of the effect of three different commercially available nano-modifiers on the mechanical properties of an epoxy/anhydride unidirectional carbon fibre reinforced laminates. The nano-modifiers consisted of an organo-modified layered silicate, vapour grown carbon fibre (VGCF) and a triblock copolymer (SBM). The work has shown that tensile modulus exhibited little difference between the unmodified laminates while a modest decrease was observed for the tensile strength. Properties related to the toughness of the matrix, demonstrated improvements compared to the unmodified laminate such as the notch sensitivity under compression, ILSS and G(IIC) performance. The improvement of the G(IIC) for the VGCF modifier in particular was found to be over 100%. It was suggested that high aspect ratio of the nano-additive helped to constrain the growth of the micro-cracks which in turn delayed failure. Mode I G(IC) performance however, was found to decrease as a result of the fibre tows preventing optimum dispersion of the modifier. The effect of this was a very high "effective" clay concentration in the interlayer resin rich regions and a less than optimum fibre dispersion, results in promotion of the propagating crack rather than inhibition

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Observed versus fitted probabilities of <i>A</i>. <i>fabae</i> prey eaten by <i>Propylea quatuordecimpunctata</i>.

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    <p>Data fitted to Holling type II (H2,) Crowley-Martin (CM), Beddington-DeAngelis (BD) and Hassell-Varley (HV) models (<i>P</i> denotes the predator density).</p

    Protecting Animals 36: Author Witi Ihimaera

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    In this very special episode of Knowing Animals I am joined by beloved New Zealand author Witi Ihimaera. Witi has written many books featuring nonhuman animals. He offers us a non-colonial lens through which to think about the human/nonhuman relationship

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries

    Author in Essay by I. A. Goncharov “Pepiniere”

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    Features of the embodiment of the author’s position in the essay by I. A. Goncharov “Pepiniere” are considered. The relevance of the study is due to the poorly studied poetics of this work. A review of the scientific literature on relevant topics is performed. Methodological and theoretical definitions are given. The scientific novelty of the article is in the fact that for the first time attention is paid to artistic techniques that allow to identify the author's position in the specified literary text. The author of the article grounds her opinion from the fact that, despite the dominance of the subjective point of view, other characters’ views stand out in the work. It is concluded in the study that the text of the work represents a biographical author and author-creator. It was established that the position of the author-creator is expressed through the title, epigraphs, which are quotes, as well as through different points of view, including the author-character, the author-narrator, the characters of the work. The author of the article dwells in detail on different ways of expressing the points of view of the author-character and the author-narrator. It is proved that the point of view of the author-character and the author-narrator can intersect, they are interchanged. The author's development of the term comic “point of view” is presented in the article
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