122,050 research outputs found
Nota a Cassazione, 21 marzo 1989, n. 1417
No full textLa nota presenta un quadro dello stato di dottrina e giurisprudenza sul tema "classico" della sorte delle operazioni attive e passive effettuate sul conto corrente bancario dell'imprenditore successivamente alla sua dichiarazione di fallimento
Du schéma Vanoni aux amorces d'une planification active
No full textPapi Ugo. Du schéma Vanoni aux amorces d'une planification active. In: Revue économique, volume 16, n°3, 1965. pp. 391-423
Structure-function studies of MICAL, the unusual multidomain flavoenzyme involved in actin cytoskeleton dynamics
No full textMICAL (from the Molecule Interacting with CasL) indicates a family of multidomain proteins conserved from insects to humans, which are increasingly attracting attention for their participation in the control of actin cytoskeleton dynamics, and, therefore, in the several related key processes in health and disease. MICAL is unique among actin binding proteins because it catalyzes a NADPH-dependent F-actin depolymerizing reaction. This unprecedented reaction is associated with its N-terminal FAD-containing domain that is structurally related to p-hydroxybenzoate hydroxylase, the prototype of aromatic monooxygenases, but catalyzes a strong NADPH oxidase activity in the free state. This review will focus on the known structural and functional properties of MICAL forms in order to provide an overview of the arguments supporting the current hypotheses on the possible mechanism of action of MICAL in the free and F-actin bound state, on the modulating effect of the CH, LIM, and C-terminal domains that follow the catalytic flavoprotein domain on the MICAL activities, as well as that of small molecules and proteins interacting with MICAL
Il crocifisso come simbolo della laicità dello Stato : commento a Tar Veneto, sezione 3., sentenza 17 marzo 2005, n. 110
No full textLaicità e libertà di educazione : il crocifisso nelle aule scolastiche in Italia e in Europa
No full textIl presente lavoro approfondisce il significato del principio di laicità in Italia e in Europa a partire dalla controversia sorta a seguito della esposizione del crocifisso nelle aule scolastiche del nostro paese, e quindi anche in riferimento alla libertà di educazione riconosciuta dalle norme della Convenzione europea dei diritti dell’uomo. Seguendo questa prospettiva, il presente contributo cerca di definire il significato pratico del principio di laicità in Italia e in Europa, ricostruendone il ruolo di metodo capace di garantire i valori del pluralismo religioso e culturale. che costituiscono una necessità imprescindibile delle democrazie moderne
Didier Vanoni et Christophe Robert. Logement et cohésion sociale. Le mal-logement au cœur des inégalités.
No full textChauffaut Delphine. Didier Vanoni et Christophe Robert. Logement et cohésion sociale. Le mal-logement au cœur des inégalités.. In: Recherches et Prévisions, n°94, 2008. Politiques du logement : questions sociales. pp. 131-133
Cavagnaro Vanoni (L.), Tombe tarquiniesi di età ellenistica. Catalogo di ventisei tombe a camera scoperte dalla Fondazione Lerici in località Calvario, 1996
No full textJannot Jean-René. Cavagnaro Vanoni (L.), Tombe tarquiniesi di età ellenistica. Catalogo di ventisei tombe a camera scoperte dalla Fondazione Lerici in località Calvario, 1996. In: Revue des Études Anciennes. Tome 101, 1999, n°1-2. pp. 285-286
Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain
No full textCrystal structures of glutamate synthase suggested that a conserved glutamyl residue of the synthase domain (E1013 of Synechocystis sp. PCC 6803 ferredoxin-dependent glutamate synthase, FdGltS) may play a key role in activating glutamine binding and hydrolysis and ammonia transfer to the synthase site in this amidotransferase, in response to the ligation and redox state of the synthase site. The E1013D, N, and A, variants of FdGltS were overproduced in Escherichia coli cells, purified, and characterized. The amino acyl substitutions had no effect on the reactivity of the synthase site nor on the interaction with ferredoxin. On the contrary, a dramatic decrease of activity was observed with the D (similar to 100-fold), N and A (similar to 10000-fold) variants, mainly due to an effect on the maximum velocity of the reaction. The E1013D variant showed coupling between glutamine hydrolysis at the glutaminase site and 2-oxoglutarate-dependent L-glutamate synthesis at the synthase site, but a sigmoid dependence of initial velocity on L-glutamine concentration. The E1013N variant exhibited hyperbolic kinetics, but the velocity of glutamine hydrolysis was twice that of glutamate synthesis from 2-oxoglutarate at the synthase site. These results are consistent with the proposed role of E1013 in signaling the presence of 2-oxoglutarate (and reducing equivalents) at the synthase site to the glutaminase site in order to activate it and to promote ammonia transfer to the synthase site through the ammonia tunnel. The sigmoid dependence of the initial velocity of the glutamate synthase reaction of the E1013D mutant on glutamine concentration provides evidence for a participation of glutamine in the activation of glutamate synthase during the catalytic cycle
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