197,018 research outputs found
Il gas naturale nel condizionamento - La valutazione economica delle pompe di calore ad azionamento termico
Il gas naturale nel condizionamento - La valutazione economica delle pompe di calore ad azionamento termico
Energetic and economic analysis of integrated systems for municipal solid waste management
SYNOPSIS: In order to solve the problem represented by Municipal Solid Waste (MSW) management, it is now common to utilise an integrated management scheme. Integrated systems for MSW management are extremely complex. However, they also represent a very interesting potential resource, from both energy and economic viewpoints. Thus, proper planning of the integrated cycle as a whole is of fundamental importance. This paper focuses on the development of a model for the analysis and optimisation of integrated cycles for MSW treatment. This objective is pursued through an assessment of the entire MSW life cycle. An application is also presented, in the form of a case-study of the Italian Region of Campania, which appears to be of particular interest, due to the recent start of a new regional plan for waste treatment, recycling and disposal. © 2004 Taylor & Francis Group, LLC
Studio di fattibilità e convenienza economica della cogenerazione al servizio degli impianti di climatizzazione
Studio di fattibilità e convenienza economica della cogenerazione al servizio degli impianti di climatizzazione
Flow boiling of R22, R134a, R507,R404A and R410A inside a smooth horizontal tube
Abstract
Flow boiling heat transfer coefficients of R22, R134a, R507, R404A and R410A inside a smooth horizontal tube (6 mm I.D., 6 m length) were measured at a refrigerant mass flux of about 360 kg/m2 s varying the evaporating pressure within the range 3–12 bar, with heat fluxes within the range 11–21 kW/m2. The experimental data are discussed in terms of the heat transfer coefficients as a function of the vapour quality. The experimental results clearly show that the heat transfer coefficients of R134a are always higher than those pertaining to R22 (from a minimum of 6 to a maximum of 45%)
The Paragon-HF trial: The sacubitril/valsartan in heart failure with preserved ejection fraction
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical condition characterized by large pathophysiology heterogeneity with lack of effective therapies as proven by the disappointing results generated by randomized controlled trials. The innovative therapeutic concept provided by sacubitril-valsartan, a molecule combining angiotensin receptor blocking agent and neprilysin inhibitor has suggested the hypothesis it would have led to a reduced risk of hospitalization for HF or death from cardiovascular causes among patients with HF and preserved ejection fraction. The PARAGON-HF (ClinicalTrials.gov number, NCT01920711) investigated HF subjects class II to IV HF, ejection fraction of 45% or higher, elevated level of natriuretic peptides, and structural heart disease to receive sacubitril-valsartan (target dose, 97 mg of sacubitril with 103 mg of valsartan twice daily) or valsartan (target dose, 160 mg twice daily). The trial missed the primary outcome of cardiovascular death and HF hospitalization (HFH) in the overall study population. A subgroup analysis addressed significant decrease of HFH in subjects with left ventricular ejection fraction below the median 57% value in the study. The data were consistent with previous post hoc analysis performed in studies where candesartan and spironolactone were investigated in HFpEF. Those results open the door to investigate angiotensin aldosterone and peptidases inhibition efficacy in the unexplored HF middle range ejection fraction, currently lacking of valid evidence
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