3,080 research outputs found
Hydrological modeling for the regional stormwater management plan: an application and intercomparison of event based runoff generation in an urban catchment using empirical, lumped vs. physical, distributed parameter modeling
No full textHydrologic modeling for the characterization of two Regional Stormwater Management Plans is performed using both a lumped parameter, empirical model and a fully distributed, physical model. Both urban/suburban watersheds located in the Northeast United States contain impaired waters, impervious surfaces ranging from 15 to 25% of total land area and are officially un-gauged. Event based models performed on storms that range from 0.5 to 1.25 inches total depth were modeled to compare the resultant simulation hydrographs of the HEC-HMS model to the MIKE-SHE model. The results of the calibrated model predictions compared well with the observed stream flow in the lumped parameter model, but were less accurate in simulating soil infiltration parameters and impervious surfaces in the fully distributed model. Sensitivity analysis of the lumped parameter model indicated that the empirical parameter representing infiltration and runoff had the greatest effect on the accuracy of the event hydrograph. The parameter that most affected accurate simulation of the overland flow in the fully distributed, physical model was the land roughness coefficient, Manning M. When the impervious surfaces and unsaturated zone were included in the fully distributed model, the hydraulic conductivity became the principal element of calibration.Ph.D.Includes bibliographical references (p. 132-139)by Sandra M. Goodro
Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)
No full textMoritella viscosa is the causative agent of winter ulcer disease in salmonids reared in North-Atlantic countries. In this study the effects of selected M. viscosa antigens on cytotoxicity and pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) macrophage-like cell line (SHK-1) were examined. SHK-1 cells were stimulated with live and heat-killed bacterial cells, extracellular products (ECP) and an extracellular vibriolysin, termed MvP1. Following incubation, cytotoxicity and expression levels of interleukin-1β (IL-1β) and interleukin-8 (IL-8) were examined at different time points. Both live M. viscosa cells and ECP were cytotoxic, but neither heat-killed cells, nor the MvP1 peptidase caused cell death. Expression levels of both IL-1β and IL-8 increased significantly after stimulation with live cells, but heat-killed cells only caused increased IL-8 expression. ECP did not affect IL-1β expression, but did stimulate IL-8 expression. The isolated MvP1 peptidase stimulated both IL-1β and IL-8 expression at the highest concentration tested. This study reveals a difference in the induction of pro-inflammatory gene expression in salmon SHK-1 cells between live and heat-killed M. viscosa cells, and also that an unknown secreted factor is the main stimulant of IL-β and IL-8 expression.ID: S1050464809000990; M3: Article; Accession Number: S1050464809000990; Author: Bryndis Bjornsdottir (a, b); Author: Mark D. Fast (b, 1); Author: Sandra A. Sperker (b); Author: Laura L. Brown (b, 2); Author: Bjarnheidur K. Gudmundsdottir (a, ∗); Affiliation: Institute for Experimental Pathology, University of Iceland, Keldur v/Vesturlandsveg, 112 Reykjavík, Iceland; Affiliation: National Research Council Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 2Z1, Canada; Keyword: Moritella viscosa; Keyword: Extracellular products; Keyword: MvP1 vibriolysin; Keyword: Atlantic salmon; Keyword: SHK-1; Keyword: Gene expression; Keyword: Immune response; Keyword: Pro-inflammatory cytokine; Keyword: Interleukin-1β (IL-1β); Keyword: Interleukin-8 (IL-8); Number of Pages: 6; Language: English;Source type: Electronic(1
Healing the land and the nation : malaria and the Zionist project in Palestine, 1920-1947 / Sandra M. Sufian.
No full textIncludes bibliographical references (p. [349]-372) and index.xviii, 385 p. :This book traces the relationships between disease, hygiene, politics, geography, and nationalism in British Mandatory Palestine between the world wars. Taking up the case of malaria control in Jewish-held lands, the author illustrates how efforts to thwart the disease were intimately tied to the project of Zionist nation-building, especially the movement's efforts to repurpose and improve its lands. The project of eradicating malaria also took on a metaphorical dimension—erasing anti-Semitic stereotypes of the “parasitic†Diaspora Jew and creating strong, healthy Jews in Palestine. The author shows that, in reclaiming the land and the health of its people in Palestine, Zionists expressed key ideological and political elements of their nation-building project. The book situates antimalarial medicine and politics within larger colonial histories. By analyzing the science alongside the politics of Jewish settlement, the author addresses contested questions of social organization and the effects of land reclamation upon the indigenous Palestinian population
First Corinthians spiritual gifts chapter 12-14 and Pentecostals of today
No full textThere is a division within the Corinthian Church in Corinth, which the Apostle Paul's (an apostle of Jesus Christ) was made aware of after receiving letters from the household of Chloe's and other church members. Paul feels responsible for the Corinthian Church members because during a visit, which lasted two years, Paul had converted its member to Christianity. Paul is told that there is great confusion over a letter he had previously wrote to the Corinthians dealing with immorality and idolatry specifically; idol meat and the pollution of idols, and the total misunderstanding of the guidelines in this letter pertaining to marriage against fornication and the separation from immoral men, along with misinterpretation of Paul's explanations of the cross, resurrection and the coming of Christ. This along with new issues caused by group distinction (follower's) and some members of the church having received the spiritual gift of tongues, which made them feel superior, because others in the church hadn't, are now major problems, that the church members are asking Paul to give them a answer and guidance to. It is in this responding letter 1st Corinthians that Paul deals with them specifically in Chapters 12-14. Also in this paper I will answer the question of whether the Modern Pentecostals of today are living by and following the Pauline Doctrines?M.A.L.S.Includes bibliographical referencesby Sandra E. Taliaferr
HighRAC workshop
No full textWith the increasing drain on natural resources and resulting aim to reduce the environmental impact of road engineering, the use of reclaimed asphalt in fresh asphalt becomes more and more important. Despite the experience in using RAC, there are still many questions regarding the effect of RAC on the technical and environmental performance of mixes, especially with high RAC content. For the true impact of RAC to be quantified, a methodology is needed for the evaluation of the possible environmental and other benefits of asphaltic mixes containing high percentages of RAC (HighRAC). For such a methodology to be precise, it will require reliable data about the durability of pavements constructed with these new types of mixtures. The HighRAC Workshop aimed to serve as a venue for a gathering of a select group of national and international experts to exchange knowledge, ideas and experience on : (i) appraisal of the long-term performance characteristics of HighRAC mixtures (ii) enhancement of the engineering properties of HighRAC mixtures by constituent material selection and/or modification at various length scales (iii) comparison and validation of current mix design procedures for mixtures containing HighRAC (iv) a holistic Life Cycle Assessment based approach for evaluation of long term pavement life including environmental and sustainability considerationsStructural EngineeringCivil Engineering and Geoscience
"Compendious extracts of strange and memorable things": sixteenth-century compilations and the new world
No full textThe sixteenth-century compilation's encyclopaedic scope embraced widely diverse texts in accounting for the newly expanded world. I examine its representational methods for what they suggest of the period's habits of thought, and consider how these shape objects of knowledge. Michel Foucault's methodological tools facilitate a critique of epistemological constructions, but his characterizations of the sixteenth-century compilation as condemned "to never knowing anything but the same thing" do not adequately account for its contested meanings and shifts in form. I consider how Martin Waldseemüller deftly arranges disparate texts to authorize Vespucci's account of the New World and his map, announcing "America," managing the unsettling discrepancies between received knowledge and new ways of describing the world.Compilations instructing in the "arte" of navigation (Taisnier, Cortés) invoke the mathematical number's abstractions in the face of shifting landscapes, demonstrating that "knowing" is caught up with "doing." I caution against reading backwards through imperial history, assuming epistemological certainties. In Sebastian Münster's Treatyse of the Newe India, the presence of human subjects troubles cosmographical certainties, while also providing objects of curiosity for natural history. The possibilities of knowing become both troubled and enabled through encounter, evident also in Cabot's instructions to explorers. I analyze relational terms (novel, ancient, strange, monstrous, "our," beastly, peculiar, gentle, humane, barbarous, infidel), as the basis of Europe's identifications. Richard Hakluyt's early compilations, Divers voyages and Principall Navigations, create the possibility of a nation-specific imperial identity, through the gathering of texts.Close reading does not always bear out the rigidly temporal shifts identified by critics. While firsthand "experience" and "novelty" carry cachet, texts flaunting their novelty often echo existing texts. The ancients' authority remains an oft-cited method of authorizing disputed material, alongside methods considered new -- the mathematical number, instrumentation to measure the world, diagrammatic forms of representation (maps, astronomical charts) and narrative eye-witness accounts. The powerful critical methods of revisionist analysis warrant a recognition of the inevitably provisional nature of these abstractions and particularized investigations. Today as in the past, what we "know" to be "true" is a function of our institutional and political context. The coherence of our insights is always, inevitably, open to question.Ph.D.Includes bibliographical references (p. 234-243)
Creer en la cura: Eficacia simbólica y control social en las prácticas del Dr. M.
No full textThe author analyze the symbolic efficacy and disciplinary and public control, in the case of experimental stem cell therapy conducted by Dr. M., Argentine immunology physician. The information has been collected from unconventional sources like forums on the Internet with patients seeking cure for their ailments, and conventional sources like newspaper articles, regulations and court records. It will address a set of events that take place in the period 2005-2010. Development will not be exhaustive, but through a process of selection of those events, paragraphs and stories that are more illustrative to account for the processes that seek to understand. It is of interest to It is of interest to retrieve the arguments the various actors put forward, for and against the practices of Dr. M., to assess actions and resultsLa autora analiza la eficacia simbólica y el control disciplinario y público, en el caso de terapéutica experimental con células madre llevada a cabo por el Dr. M., médico inmunólogo argentino. La información ha sido recogida de una fuente no convencional como los foros en Internet de pacientes en busca de cura para sus dolencias, y de fuentes convencionales como artículos periodísticos, normativas y expedientes judiciales. Se abordarán un conjunto de eventos que transcurren en el período 2005-2010. El desarrollo no será exhaustivo, sino mediante un proceso selectivo de aquellos eventos, párrafos y narraciones que resulten más ilustrativas para dar cuenta de los procesos que se pretenden comprender. Es de interés recuperar los argumentos a favor y en contra de las prácticas del Dr. M. que los distintos actores esgrimen para evaluar las acciones y sus resultados.Fil: Krmpotic, Claudia Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro Argentino de Etnología Americana; Argentin
Creer en la cura: Eficacia simbólica y control social en las prácticas del Dr. M.
No full textThe author analyze the symbolic efficacy and disciplinary and public control, in the case of experimental stem cell therapy conducted by Dr. M., Argentine immunology physician. The information has been collected from unconventional sources like forums on the Internet with patients seeking cure for their ailments, and conventional sources like newspaper articles, regulations and court records. It will address a set of events that take place in the period 2005-2010. Development will not be exhaustive, but through a process of selection of those events, paragraphs and stories that are more illustrative to account for the processes that seek to understand. It is of interest to It is of interest to retrieve the arguments the various actors put forward, for and against the practices of Dr. M., to assess actions and resultsLa autora analiza la eficacia simbólica y el control disciplinario y público, en el caso de terapéutica experimental con células madre llevada a cabo por el Dr. M., médico inmunólogo argentino. La información ha sido recogida de una fuente no convencional como los foros en Internet de pacientes en busca de cura para sus dolencias, y de fuentes convencionales como artículos periodísticos, normativas y expedientes judiciales. Se abordarán un conjunto de eventos que transcurren en el período 2005-2010. El desarrollo no será exhaustivo, sino mediante un proceso selectivo de aquellos eventos, párrafos y narraciones que resulten más ilustrativas para dar cuenta de los procesos que se pretenden comprender. Es de interés recuperar los argumentos a favor y en contra de las prácticas del Dr. M. que los distintos actores esgrimen para evaluar las acciones y sus resultados.Fil: Krmpotic, Claudia Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro Argentino de Etnología Americana; Argentin
Author correction: obesity and ethnicity alter gene expression in skin
No full textDaniel Butler was omitted from the author list in the original version of this Article. The Author contributions section now reads: “J.M.W. designed, conducted, and contributed to the writing of the manuscript, prepared Fig. 1. S.G. evaluated and did statistical analysis on the skin and fat samples, prepared Figs. 2–9. J.O.A. evaluated and contributed to writing the manuscript. D.B prepared and sequenced DNA libraries for the skin microbiota data, and wrote the applicable parts of the methods section. C.M. analyzed and wrote up the skin microbiota data, prepared Fig. 10. All authors have read the manuscript and approved its contents. D.D. analyzed and wrote up the skin microbiota data. S.Z. ran and analyzed the skin metabolite data. J.S. assisted in design, analysis and wrote up the skin metabolite data. J.K. assisted in analysis write up of skin and fat data. J.L.B. assisted in analysis, interpretation and writing of the manuscript. P.R.H. designed, analyzed, interpreted the data, and was the primary author of the manuscript.” This has been corrected in the PDF and HTML versions of the Article, and in the accompanying Supplementary Information file.</p
Validation of co-oximetry for methemoglobin measurement in rainbow trout and the investigation of benzocaine as a cause of methemoglobin in salmonids
No full textAbstract not available.Source: Masters Abstracts International, Volume: 50-04, page: 2294.Advisers: Sandra McConkey; Dave Speare
- …
