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Contact sensitization to 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one in children
No full textIn adults, MCI/MI sensitization is most common among females and in patients with facial and hand dermatitis (1). In our study, girls were more commonly affected than boys, and 6 of 7 patients had hand dermatitis. Most cases of contact allergy appear induced by leave-on cosmetics, especially moisturizing creams and wet wipes.
The frequency of MCI/MI sensitization in our study is higher than that reported in other studies on children (28) (Table 1). This variation may be explained by different patient selection and the varying use of the preservative in different countries. Our study included only children with a suspected diagnosis of contact dermatitis rather than non-eczematous children or children with other types of eczema (4, 8).
In Italy, there are still many cosmetic brands for babies and children containing MCI/MI as preservative, including wet wipes, protective creams, liquid soaps and shampoos
Contact dermatitis due to topical cosmetic use of vitamin K
No full textVitamin K exists in 4 different forms: vitamin K1 (phytomenadione), the natural form; vitamin K2 (menaquinone) from intestinal bacterial synthesis; and vitamin K3 (menadione) and K4 (menadiol) as synthetic analogues (1). The lipid-soluble vitamin K (phytomenadione) causes more cutaneous reations than its water-soluble analogues (2). In previous reports, cutaneous hypersensitivity reactions to injection of vitamin K were seen in patients with liver disease, suggesting a relationship (1). There are also reported cases of cutaneous reactions to vitamin K1 after its intramuscular injection in patients who have it for hypothrombinemia without liver disease (1, 3). Reactions to water soluble vitamin K are less common, because vitamin K is absorbed through the skin (2).
Contact dermatitis due to vitamin K for topical use is uncommon and only a few cases of occupational contact dermatitis from vitamin K3 have been so reported (46). All such cases were in employees in veterinary and pharmaceutical laboratories who had contact with the vitamin in their work. In these cases, the form of vitamin K is always K3 (menadione), which also, in high enough concentration, causes an irritant contact dermatitis (2).
No cases of allergic contact dermatitis due to vitamin K1 for topical cosmetic use have previously been reported
Hypertrichosis of the eyelashes caused by bimatoprost
No full textThe phenyl-substituted analog of prostaglandin F 2alpha , latanoprost (Xalatan; Pfizer, Inc, New York, NY) is an intraocular pressure (IOP)-lowering drug for use in patients with glaucoma and ocular hypertension. Latanoprost has been shown to stimulate eyelash hypertrichosis and has recently been proposed as a possible treatment for alopecia areata involving the eyelashes. We report a case of hypertrichosis of the eyelashes caused by the prostamide bimatoprost (Lumigan; Allergan, Inc, Irvine, Calif), a new IOP-lowering drug
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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Contact dermatitis due to cyclohexanone: a further case
No full textCyclohexanone (synonyms: anone, hexanone, ketohexamethylene, nadone, pimelic ketone and setone) is a synthetic organic liquid used primarily as an intermediate in the production of nylon. Other minor applications are as an intermediate, additive and solvent in a variety of products. Occupational exposure is possible in some industries. A typical use of this substance is as a polyvinyl chloride (PVC) solvent to facilitate the gluing of materials to plastic. A case of contact allergy to cyclohexanone was described in 1992 (1). We now report a further case
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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