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Dialoghi filosofici by Antonio Conti: a Margin Note to a Recent Edition
No full textDialoghi filosofici, the last and unfinished work of the Paduan abbot Antonio Conti, are now available for the first time thanks to a carefully annotated and critical edition. It is thus possible to appreciate the variety of philosophical, scientific and literary themes involved, which in turn are the outcome of one of the most original and dynamic intellectual adventures of the early 18th century in Europe
La lettera di Francesco Barbaro a Lorenzo Monaci. Prodromi del progetto di traduzioni dal greco di Niccolo V nel sesto centenario della nascita
No full text"Simillima pestis Florentie et quasi per universum orbem": Boccaccio e la Historia Langobardorum di Paolo Diacono
Full text linkThis paper deals with the recently discovered Boccaccio’s autograph of Paul the Deacon’s Historia Langobardorum, the manuscript LONDON, British Library, Harley 5383. Along with its membra disiecta FIRENZE, Biblioteca Riccardiana, 627 and 2795VI, it forms a handbook of ancient, roman and mediaeval history (besides the Historia Langobardorum, Paul Orose’s Historiae adversus paganos, Paul the Deacon’s Historia Romana, books XIII-XVI, Pasquale Romano’s brief epistle De origine civitatis Aretii) almost entirely copied by Boccaccio.
After recalling the circumstances of its finding, the paper points out that text of Historia Langobardorum contained in Harley 5383 and in its membrum disiectum Riccard. 2795VI is abridged, more than the 20% of its chapters missing or being epitomized; whether Boccaccio was also the author of this version of Paul the Deacon’s work or simply its scribe remains under discussion
Ospemifene in the management of vulvar and vaginal atrophy: Focus on the assessment of patient acceptability and ease of use
Full text linkEndocrinological changes that occur with menopause lead to a chronic and progressive condition named vulvar and vaginal atrophy (VVA). This disease is characterized by symptoms such as dryness, dyspareunia, itching, burning, and dysuria. According to recent epidemiological studies, VVA has a high prevalence and can also occur in younger women prior to the menopause, negatively affecting quality of life, sexual function, intimacy and relationship with the partner. Accordingly, therapy should be effective, initiated early and continued for as long as possible. Up to recent years, available therapeutic options have included over-the-counter lubricants and moisturizers, vaginal oestrogens and systemic hormones. These products are not indicated for all women. Hormones are mostly contraindicated in women with a history of hormone-sensitive cancer and are frequently not accepted even by women without contraindications. Local therapies are frequently considered uncomfortable, difficult to apply, and messy. Indeed, these treatments have a high spontaneous discontinuation rate, mostly due to dissatisfaction, safety concern, side effects and difficulty in vaginal placement. Recently, ospemifene, a new non-hormonal systemic remedy, was approved by FDA (Food and Drug Administration) and EMA (European Medicines Agency) for the treatment of the two most bothersome symptoms of VVA: dryness and dyspareunia. Because ospemifene is a selective estrogen receptor modulator (SERM), it can be administered also in women with a history of breast cancer, and this makes it more acceptable by any woman. In addition, its route of administration minimizes those bothersome side effects intrinsic to the vaginal route of administration. Available data indicate that women using ospemifene have higher adherence to treatment, higher persistence and lower discontinuation rate. Satisfaction is higher than with other local therapies and overall health care cost is lower
The Controversial History of Hormone Replacement Therapy
No full textThe history of hormone replacement therapy (HRT) started in the 1960s, with very high popularity in the 1990s. The first clinical trials on HRT and chronic postmenopausal conditions were started in the USA in the late 1990s. After the announcement of the first results of the Women’s Health Initiative (WHI) in 2002, which showed that HRT had more detrimental than beneficial effects, HRT use dropped. The negative results of the study received wide publicity, creating panic among some users and new guidance for doctors on prescribing HRT. The clear message from the media was that HRT had more risks than benefits for all women. In the following years, a reanalysis of the WHI trial was performed, and new studies showed that the use of HRT in younger women or in early postmenopausal women had a beneficial effect on the cardiovascular system, reducing coronary disease and all-cause mortality. Notwithstanding this, the public opinion on HRT has not changed yet, leading to important negative consequences for women’s health and quality of life
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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