197,053 research outputs found

    Effects of electrical charging on the mechanical Q of a fused silica disk

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    We report on the effects of an electrical charge on mechanical loss of a fused silica disk. A degradation of Q was seen that correlated with charge on the surface of the sample. We examine a number of models for charge damping, including eddy current damping and loss due to polarization. We conclude that rubbing friction between the sample and a piece of dust attracted by the charged sample is the most likely explanation for the observed loss.Michael J. Mortonson and Christophoros C. Vassiliou, David J. Ottaway, David H. Shoemaker and Gregory M. Harr

    Stormwater retention and reuse at the residential plot level-green roof experiment and water balance computations for long-term use in Cyprus

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    Green roofs can provide various benefits to urban areas, including stormwater retention. However, semi-arid regions are a challenging environment for green roofs as long dry weather periods are met with short but intense rainfall events. This requires green roofs to retain maximum volumes of stormwater, while being tolerant to minimal irrigation supplies. The objectives of this study are (i) to quantify the stormwater retention of two substrate mixtures with two plant species under natural rainfall; (ii) to assess the performance of two plant species under two levels of deficit irrigation; and (iii) to compute stormwater runoff reduction and reuse by green roofs and rooftop water harvesting systems for three standard residential plot types in urban Nicosia, Cyprus. A rooftop experiment was carried out between February 2016 and April 2017 and results were used to compute long-term performance. Average stormwater retention of the 16 test beds was 77% of the 371-mm rainfall. A survival rate of 88% was recorded for Euphorbia veneris and 20% for Frankenia laevis, for a 30% evapotranspiration irrigation treatment. A combination of a green roof, rainwater harvesting system and 20-m3 tank for irrigation and indoor greywater use reduced stormwater runoff by 47-53%, for the 30-year water balance computations

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Fundamentals of data warehouses

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    This book presents the first comparative review of the state-of-the-art and the best current practices of data warehouses. It covers source and data integration, multidimensional aggregation, query optimization, metadata management, quality assessment, and design optimization. A conceptual framework is presented by which the architecture and quality of a data warehouse can be assessed and improved using enriched metadata management combined with advanced techniques from databases, business modeling, and artificial intelligence

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Glendon Swarthout

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    Hosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness

    Surface and interface investigation of electrochemically induced corrosion on a quaternary bronze

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    A quaternary (Cu-Zn-Sn-Pb) cast bronze was submitted to an electrochemical corrosion experiment using an anodic polarization sweep. The surface/interface chemical analysis of the patina removed after the anodic polarization and the metallographic observations on the corroded bulk alloy highlight the onset of a dezincification process followed by a decuprification process, aswell as the formation of a Sn-enriched layer located at the interface patina-bulk alloy. Different local corrosion patterns, as CuCl precipitation in pits, epitaxial growth of corrosion products on dendritic structures and of Cl-enriched oxyhydroxides, are observed too. The results are discussed in comparison with experimental findings obtained in previous ageing tests performed on the same alloy in different chloride-containing solution

    Studies on the acute porphyrias : with special reference to women’s health

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    The acute porphyrias are a group of rare inherited disorders of the metabolism of heme. Three acute porphyrias comprise most of the cases: acute intermittent porphyria (AIP), hereditary coproporphyria (HCP) and variegate porphyria (VP). All three are inherited in an autosomal dominant pattern and have a very low clinical penetrance.In a subgroup of individuals with acute porphyria, the imbalance in heme metabolism results in the accumulation of heme precursors, measured as excreted molecules in the urine. A significant accumulation of heme precursors in combination with neurovisceral symptoms such as pain and paresis constitute the acute porphyria attack. In addition to the risk of developing acute attacks, the genetic traits for acute porphyria are associated with increased risk for other comorbidities, most notably hypertensive disease, chronic kidney disease and primary liver cancer.Despite their inheritance pattern, acute porphyrias have been regarded as affecting women to a greater extent than men. This assumption was initially based on the numerous case reports of patients with severe, life-threatening disease manifestations, almost exclusively female. It has further been strengthened by the fact that women are overrepresented in symptomatic patient cohorts. The mechanisms behind such a skewed disease phenotype pattern are not entirely understood. A correlation between acute porphyria pathophysiology and the fluctuations in the hormones of the gonads, particularly progesterone, has been suggested.Progesterone fluctuates during the menstrual cycle and has been suggested as a contributing factor in making women more susceptible to acute porphyria manifestations compared to men. Progesterone levels increase manifoldly during pregnancy, and significant morbidity was reported in women with acute porphyria during pregnancy in the past. Administration of large doses of progestogens are part of fertility treatments for which reason they are still not recommended for women with acute porphyria.We set out to highlight and update the different aspects of women’s health in acute porphyria.In Study I we report of the clinical and biochemical outcomes of 44 pregnancies in 33 women with acute porphyria. Four women experienced acute attacks during pregnancy and one during the postpartum period. Seven women developed hypertension and four pregnancies ended with pre-eclampsia. The levels of heme precursor excretion were measured in 38 of the pregnancies; 32 showed an increase in the excretion of heme precursors during pregnancy. The study suggests increased risk for pregnancy-related hypertensive disease in acute porphyria and is the first report of increased biochemical activity in women with acute porphyria and asymptomatic pregnancies.In Study II the outcomes in nine women with acute porphyria that underwent fertility treatments are presented in detail. The treatments were generally well-tolerated, even though several of the agents administered are classified as porphyrinogenic.In Study III we aimed to expand our observations based on single cases and small patient cohorts to the entire population of women with acute porphyria in Sweden. We combined biochemical and genetic data from the Swedish Porphyria Register with data regarding morbidity and complications from Swedish Medical Register for all women with acute porphyria between 1987 and 2015; 214 women with acute porphyria and 2174 matched comparators were included. Women with acute porphyria presented with a higher risk for pregnancy-induced hypertensive disorder, gestational diabetes, and small-for-gestational-age birth. Those relative risks were higher in women with AIP who had increased excretion of the heme precursor porphobilinogen.For Study IV, we aimed to study the differences in disease burden by combining data from the Swedish Porphyria Register with an extensive questionnaire. The final analysis set included 534 patients - 298 women and 236 men. Both patient-reported disease outcomes, such as hospitalization, chronic symptoms, and daily life limitations due to porphyria, as well as biochemical markers of active disease showed a female predominance.List of scientific papersI. Vassiliou D, Sardh E. Acute hepatic porphyria and maternal health: Clinical and biochemical follow-up of 44 pregnancies. J Intern Med. 2022 Jan; 291(1):81-94. https://doi.org/10.1111/joim.13376 II. Vassiliou D, Lindén Hirschberg A, Sardh E. Treatment with assisted reproduction technologies in women with acute hepatic porphyria. Acta Obstet Gynecol Scand. 2021 Sep; 100(9):1712-1721. https://doi.org/10.1111/aogs.14200 III. Mantel Ä*, Vassiliou D*, Lissing M, Stephansson O, Wahlin S, Sardh E. Maternal and fetal outcomes in acute hepatic porphyria: A Swedish National Cohort Study. J Inherit Metab Dis. 2023 Jul;46(4):675-686. *Joint first authors. https://doi.org/10.1002/jimd.12616 IV. Vassiliou D, Harper P, Spelman T, Lissing M, Floderus Y, Sardh E. Acute porphyria in women: results from a Swedish national survey study. [Manuscript]</p
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