131,725 research outputs found
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Personal Papers (MS 80-0002)
No full textTelegram sent by Paul de la Vallee Poussin to General William J. D. Amancue discussing the progress of the Schuman Plan
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Interpretation of reflection attributes in a 3-D GPR survey at Vallee d'Ossau, western Pyrenees, France
No full textACLInternational audienceTo study the attributes of reflected radar waves, a 3-D ground-penetrating radar (GPR) data set was recorded, processed with ProMAX 3-D seismic processing software, and analyzed with Stratimagic 3-D seismic interpretation software. The zone studied was an old glacial valley (Vallee d'Ossau, western Pyrenees) where fluvio-glacial deposits (8-10 m thick) overlay a karstic limestone bedrock. Reflections were picked to 250 ns (9 m depth with velocity v = 0.07 m/ns). Analysis of the isochron map of the bedrock surface reflector showed north-south undulations, corresponding to the displacement of the old glacier, together with sharp discontinuities, interpreted as local faults or karstic zones. Amplitude variations along the reflector were interpreted as being from water saturation and the nearby north-south alignment of springs at the surface. In the fluvio-glacial deposits, paths of old channels were also imaged using amplitude analysis. The radar-wave amplitude attenuation was also characterized within the deposits by analyzing the average absolute amplitude for different time windows. The strong amplitude attenuations were interpreted as the result of water-saturated zones. As a conclusion, we correlated the surface karstic springs with bedrock structures and followed the water path across the glacial sedimentary filling. The recognized features were very consistent with a 2-D dc resistivity profile made through the GPR data block. To study the attributes of reflected radar waves, a 3-D ground-penetrating radar (GPR) data set was recorded, processed with ProMAX 3-D seismic processing software, and analyzed with Stratimagic 3-D seismic interpretation software. The zone studied was an old glacial valley (Vallee d'Ossau, western Pyrenees) where fluvio-glacial deposits (8-10 m thick) overlay a karstic limestone bedrock. Reflections were picked to 250 ns (9 m depth with velocity v = 0.07 m/ns). Analysis of the isochron map of the bedrock surface reflector showed north-south undulations, corresponding to the displacement of the old glacier, together with sharp discontinuities, interpreted as local faults or karstic zones. Amplitude variations along the reflector were interpreted as being from water saturation and the nearby north-south alignment of springs at the surface. In the fluvio-glacial deposits, paths of old channels were also imaged using amplitude analysis. The radar-wave amplitude attenuation was also characterized within the deposits by analyzing the average absolute amplitude for different time windows. The strong amplitude attenuations were interpreted as the result of water-saturated zones. As a conclusion, we correlated the surface karstic springs with bedrock structures and followed the water path across the glacial sedimentary filling. The recognized features were very consistent with a 2-D dc resistivity profile made through the GPR data block
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Binding of D-phenylalanine and D-tyrosine To Carboxypeptidase-a
No full textThe structures of the complexes of carboxypeptidase A with the amino acids D-phenylalanine and D-tyrosine are reported as determined by x-ray crystallographic methods to a resolution of 2.0 A. In each individual study one molecule of amino acids binds to the enzyme in the COOH-terminal hydrophobic pocket: the carboxylate of the bound ligand salt links with Arg-145, and the alpha-amino group salt links with Glu-270. The carboxylate of Glu-270 must break its hydrogen bond with the native zinc-bound water molecule in order to exploit the latter interaction. This result is in accord with spectroscopic studies which indicate that the binding of D or L amino acids (or analogues thereof) allows for more facile displacement of the metal-bound water by anions (Bicknell, R., Schaffer, A., Bertini, I., Luchinat, C., Vallee, B. L., and Auld, D. S. (1988) Biochemistry 27, 1050-1057). Additionally, we observe a significant movement of the zinc-bound water molecule (approximately 1 A) upon the binding of D-ligands. We propose that this unanticipated movement also contributes to anion sensitivity. The structural results of the current x-ray study correct predictions made in an early model building study regarding the binding of D-phenylalanine (Lipscomb, W. N., Hartsuck, J. A., Reeke, G. N., Jr., Quiocho, F. A., Bethge, P. H., Ludwig, M. L., Steitz, T. A., Muirhead, H., and Coppola, J. C. (1968) Brookhaven Symp. Biol. 21, 24-90)
THE DIALECT OF THE (Hautes-pyrenees) D' AURE : VALLEE
No full textPhDThis monograph gives a synchronistic and diachronistic
account of the present-day dialect of the Vallee d'Aure in
the Frenoh department of the Hautes-Pyrenees. The territory
investigated includes the higher and lower portions of the
basin of the Neste (Weste d'Aure and Neate proper) and the
subsidiary valley of T.Jouron(Neste de Lour-on}, After a
short lntroduction, the monograph deals with the Phonology,
Morphology and, Vocabulary of the dialect and compares a
study of the Linguistic Geography of the area under investigation.
The text is accompanied by 14 maps and is followed
by an extensive Index-Glossary of the patois with etymological
notes.Central Research fund of the University of London
Ernest Cassel Eduoational Trus
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Scholarly Communication and Publishing Lunch and Learn Talk #11: The ULS Open Access Author Fee Fund
No full textAt the May 2014 talk, you will learn about the ULS Open Access Author Fee Fund--what it is, why we do it, how it works, and how the program is going so far
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