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    Cartas sobre los asuntos mas exquisitos de la economía-política y sobre las leyes criminales

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    Nom real de l'autor: Giovanni Valentino Matteo Fabbroni.Nombre de v. obtingut de Palau

    In vitro effect of acrylonitrile on specific activities of human polymorphonuclear leucocytes.

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    N-Formyl-methionyl-leucyl-phenylalanine (F-MLP)-induced chemotaxis and luminolamplified chemiluminescence were studied in isolated human polymorphonuclear leucocytes (PMN) and exposed to acrylonitrile (ACN) in vitro. Chemotaxis was reduced at ACN concentrations of 3 mm and above, while respiratory burst was affected at ACN concentrations of 18mm and above. The ACN concentrations were highly correlated both with decreased chemotactic activity (r = 0.75; P < 0.05) and with decreased respiratory burst (r = 0.93; P < 0.01)
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