1,720,964 research outputs found

    Probiotici: possibilità di regolazione della risposta allergica

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    La prevalenza di malattie allergiche è aumentata molto negli ultimi decenni e le allergie sono ora la patologia cronica più comune nei bambini a livello mondiale. È stata dimostrata una correlazione tra la composizione della microflora intestinale e l’insorgenza di allergie, dove alcuni microrganismi sono in grado di modulare la risposta immunitaria in senso antinfiammatorio. Per questi motivi è stato ipotizzato che i probiotici possano essere efficaci nella prevenzione e nel trattamento delle allergie. Studi in vitro e trials clinici hanno mostrato numerose evidenze a favore dei probiotici. Tuttavia i benefici di questo trattamento dipendono da numerosi fattori quali il ceppo batterico, la durata della somministrazione, il tipo di prodotto, la patologia trattata, l’età e la dieta del paziente. Non essendoci ancora un candidato ideale, rimane ancora da determinare quali siano i microrganismi e le modalità di somministrazione più adatti. Questa revisione si propone di cercare di interpretare il razionale scientifico dei probiotici nelle malattie allergiche e il loro probabile ruolo in tali patologie alla luce della letteratura recente

    Microbiological evaluation of commercial probiotic products available in the USA in 2009

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    Probiotics are widely used to prevent and treat several diseases. Many commercial products are available worldwide. However, there is no clear international or local legislation about them and previous studies showed that most of the tested products are not in conformity with international guidelines. The aim of this study was to determine if products available in the USA market in 2009 were correctly labeled in terms of quantity of viable bacteria, identification of species and cross contamination by species not on the label. Disturbingly, we found that only 4 of 13 products (31%) were in accordance with label claims. Our results suggest the need for adequate control of probiotic production as well as periodical screenings by competent organizations to monitor the effect of storage on product quality

    Microbiological and genetic identification of some probiotics proposed for medical use in 2011

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    The aim of this work was to evaluate if dietary supplements for medical use available on the Italian and European market in 2011 were correctly labelled in terms of amount of viable bacteria, identity of species or genera and lack of cross contamination by species out of label. Fourteen in twenty-four products (58%) contained all the labelled species in the declared amount and were free of bacterial contamination. Ten in twenty-four products (42%) did not contain the labelled bacterial amount. Moreover, in four of these products (17%), we could not find any viable colony of at least one of the declared species. In two of them the DNA of all missing species could be detected by extracting DNA directly from the product. In conclusion, some products available on the Italian and European market in 2011 were not correctly labelled and did not comply with the specific guidelines

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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