1,721,050 research outputs found
Boxer cardiomyopathy : a study of the clinical presentation diagnostic findings and survival
Abstract Objectives: To retrospectively compare and contrast the clinical
presentation, diagnostic findings and survival in Boxer dogs with cardiomyopathy,
with or without left ventricular (LV) systolic failure.
Animals, materials and methods: Medical records of Boxers referred between 1993
and 2008 in which a diagnosis of ventricular arrhythmias and/or cardiomyopathy was
made, were reviewed. Dogs were divided into two groups according to their left
ventricular (LV) systolic diameter, groupAnormal (20 dogs) or group Bdilated (59 dogs).
Results: Dogs in group A had a better outcome than dogs in group B (median survival
time of 124 and 17 weeks respectively, p < 0.001). In group B, dogs with a history of
collapse had a worse outcome (median survival time of 10 weeks) compared with dogs
not showing collapse (median survival time 24 weeks) (p 1⁄4 0.031).
Conclusions: The majority of dogs, in this UK study, presented with the myocardial
dysfunction form of the disease, with LV dilation and congestive heart failure signs.
The prognosis was worse in dogs with LV dilation compared to dogs with a normal LV
and ventricular arrhythmias. In the Boxers with LV dilation, dogs with collapse had
a worse prognosis than those without
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
New role of the S. cerevisiae Not4p in aging and oxidative stress response
The Ccr4–Not complex has originally been described as a negative regulator of RNA polymerase II (pol II) transcription, but it has also been implicated in mRNA turnover and protein ubiquitination.
We found that not4 and ccr4 mutants have an extended longevity during chronological aging and an increased resistance to oxidative stress. This increased resistance is due only in part to the loss of control on MSN2/4-driven transcription in that triple mutants not4/msn2/4 still exhibit these phenotypes. Altogether these data support the idea that CCR4/NOT complex is important in keeping down stress response controlling cell proliferation
Analisi dell'andamento della troponina I sierica in cani sottoposti a correzione del dotto arterioso pervio : indagini preliminari
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