192 research outputs found

    Diagnostic bronchoscopy: state of the art

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    Since the introduction of the flexible fibreoptic bronchoscope in the late 1960s there have been relatively few technological advances for three decades, aside from the development of a white light video bronchoscope with a miniature charge-coupled device built in its tip replacing the fibreoptics. White light flexible videobronchoscopy with its ancillary devices (forceps biopsy, bronchial brushing, bronchoalveolar lavage, bronchial washings and transbronchial needle aspiration) has long been the only established diagnostic bronchoscopic technique. With the advances in microtechnology over the past two decades, recent technical developments such as autofluorescence bronchoscopy and endoscopic ultrasound allow better evaluation of endobronchial, mediastinal and parenchymal lesions

    Les traitements palliatifs et curatifs en endoscopie bronchique

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    Endoscopic management of carcinoma in situ or microinvasive carcinoma of the central airways is generally performed in patients who are not candidates for resection. Curative treatment can be obtained with different techniques and can be expected when the lesion is superficial, of small size and corresponds to in situ or microinvasive carcinoma. Endoscopic treatment is also indicated to relieve airway obstruction in order to palliate dyspnea. This review discusses the indications, the results of different technologies and their complications.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice

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    Didier Cataldo,1 Eric Derom,2 Giuseppe Liistro,3 Eric Marchand,4,5 Vincent Ninane,6 Rudi Peché7 Hans Slabbynck,8 Walter Vincken,9 Wim Janssens10 1Department of Respiratory Medicine, Centre Hospitalier Universitaire de Liège (CHU) and University of Liège, Liège, Belgium; 2Department of Respiratory Medicine, Ghent University Hospital, Gent, Belgium; 3Department of Respiratory Medicine, University Hospitals Saint-Luc, Brussels, Belgium; 4Department of Respiratory Medicine, University Hospital UCL Namur, Yvoir, Belgium; 5URPhyM, University of Namur, Namur, Belgium; 6Department of Respiratory Medicine, University Hospital Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium; 7Department of Respiratory Medicine, University Hospital Vésale, Montigny-le-Tilleul, Belgium; 8Department of Respiratory Medicine, ZNA Middelheim, Antwerpen, Belgium; 9Respiratory Division, University Hospital Brussels (UZ Brussel), Vrije Universiteit Brussel, Brussels, Belgium; 10Department of Respiratory Medicine, University Hospitals Leuven, Leuven, Belgium Abstract: Evidence and guidelines are becoming increasingly clear about imbalance between the risks and benefits of inhaled corticosteroids (ICSs) in patients with COPD. While selected patients may benefit from ICS-containing regimens, ICSs are often inappropriately prescribed with – according to Belgian market research data – up to 70% of patients in current practice receiving ICSs, usually as a fixed combination with a long-acting β2-adrenoreceptor agonist. Studies and recommendations support withdrawal of ICSs in a large group of patients with COPD. However, historical habits appear difficult to change even in the light of recent scientific evidence. We have built a collaborative educational platform with chest physicians and primary care physicians to increase awareness and provide guidance and support in this matter. Keywords: COPD, exacerbation, withdrawal, inhaled steroids, systematic review, educatio

    Physics of Atomic Nuclei V. 66, I. 08

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    Physics of Atomic Nuclei -- August 2003 Volume 66, Issue 8, pp. 1399-1589 The ALTO Project at IPN Orsay F. Ibrahim pp. 1399-1406 Full Text: PDF (587 kB) Physics with Fission Fragments: Project DRIBs-2 Yu. E. Penionzhkevich pp. 1407-1412 Full Text: PDF (235 kB) Isotopic Production Cross Sections of Residues in Reactions Induced by Relativistic Heavy Ions with Protons and Deuterons E. Casarejos, P. Armbruster, L. Audouin, J. Benlliure, M. Bernas, A. Boudard, R. Legrain, S. Leray, B. Mustapha, S. Czajkowski, T. Enqvist, B. Fernandez, J. Pereira, M. Pravikoff, F. Rejmund, K.-H. Schmidt, C. Stephan, J. Taieb, L. Tassan-Got, C. Villagrasa, C. Volant, and W. Wlazlo pp. 1413-1420 Full Text: PDF (405 kB) Decay of Neutron-Rich Ga Isotopes near N=50 at PARRNe O. Perru, F. Ibrahim, O. Bajeat, C. Bourgeois, F. Clapier, E. Cottereau, C. Donzaud, M. Ducourtieux, S. Galès, D. Guillemaud-Mueller, C. Lau, H. Lefort, F. Le Blanc, A. C. Mueller, J. Obert, N. Pauwels, J. C. Potier, F. Pougheon, J. Proust, B. Roussière, J. Sauvage, O. Sorlin, and D. Verney pp. 1421-1427 Full Text: PDF (429 kB) A Study of gammaDecays and Octupole Bands in 21Ne and 21Na S. Thummerer, W. von Oertzen, Tz. Kokalova, H. G. Bohlen, B. Gebauer, A. Tumino, T. N. Massey, G. de Angelis, M. Axiotis, A. Gadea, Th. Kröll, N. Marginean, D. R. Napoli, M. De Poli, C. Ur, D. Bazzacco, S. M. Lenzi, C. Rossi Alvarez, S. Lunardi, R. Menegazzo, P. G. Bizzeti, and A. M. Bizzeti-Sona pp. 1428-1433 Full Text: PDF (167 kB) Separable Skyrme Interactions and Quasiparticle RPA A. P. Severyukhin, V. V. Voronov, Ch. Stoyanov, and Nguyen Van Giai pp. 1434-1438 Full Text: PDF (138 kB) Clustering in the Region of Nuclear Surface V. G. Kartavenko, K. A. Gridnev, J. Maruhn, and W. Greiner pp. 1439-1444 Full Text: PDF (169 kB) Study of Giant Pairing Vibrations with Neutron-Rich Nuclei L. Fortunato pp. 1445-1449 Full Text: PDF (171 kB) New Experimental Results on Emission and Reaction Barriers N. Rowley pp. 1450-1453 Full Text: PDF (138 kB) Dynamics of Superheavy System in 86Kr+208Pb Reaction V. A. Rubchenya, A. A. Alexandrov, S. V. Khlebnikov, V. G. Lyapin, V. A. Maslov, Yu. E. Penionzhkevich, G. Prete, Yu. V. Pyatkov, Yu. G. Sobolev, G. P. Tiourin, W. H. Trzaska, D. N. Vakhtin, and J. Äystö pp. 1454-1459 Full Text: PDF (258 kB) Isospin Effects in Nuclear Fragmentation V. Baran, M. Colonna, M. Di Toro, V. Greco, M. Zielinska-Pfabe, and H. H. Wolter pp. 1460-1470 Full Text: PDF (206 kB) Determination of the Freeze-Out Temperature by the Isospin Thermometer P. Napolitani, K.-H. Schmidt, P. Armbruster, A. S. Botvina, M. V. Ricciardi, L. Tassan-Got, F. Rejmund, and T. Enqvist pp. 1471-1477 Full Text: PDF (353 kB) Nuclear Rainbow in Scattering and Reactions and Nucleus–Nucleus Interaction at Small Distances A. A. Ogloblin, S. A. Goncharov, Yu. A. Glukhov, A. S. Dem'yanova, M. V. Rozhkov, V. P. Rudakov, and W. H. Trzaska pp. 1478-1488 Full Text: PDF (306 kB) Rainbow, Airy Structure, and Molecular Structure in the 16O+16O System S. Ohkubo pp. 1489-1493 Full Text: PDF (160 kB) Structure of Neutron-rich Be and C Isotopes H. G. Bohlen, W. von Oertzen, R. Kalpakchieva, B. Gebauer, S. M. Grimes, A. Lenz, T. N. Massey, M. Milin, Ch. Schulz, Tz. Kokalova, S. Torilov, and S. Thummerer pp. 1494-1500 Full Text: PDF (253 kB) Structure Studies of Exotic Nuclei Using (p,p') Reactions V. Lapoux, N. Alamanos, and E. Khan pp. 1501-1507 Full Text: PDF (238 kB) Structure of 10C and 11C from Elastic and Inelastic Scattering on a Proton Target C. Jouanne, N. Alamanos, F. Auger, A. Drouart, A. Gillibert, V. Lapoux, G. Lobo, L. Nalpas, E. C. Pollacco, J. L. Sida, Y. Blumenfeld, E. Khan, T. Suomijarvi, T. Zerguerras, A. Lagoyannis, A. Pakou, P. Roussel-Chomaz, H. Savajols, and A. Musumarra pp. 1508-1514 Full Text: PDF (325 kB) Proton Halos in Exotic Light Nuclei Z. Ren, X. Z. Cai, H. Y. Zhang, and W. Q. Shen pp. 1515-1518 Full Text: PDF (110 kB) Two-Proton Radioactivity Search I. G. Mukha pp. 1519-1522 Full Text: PDF (131 kB) The Present and Planned Recoil Mass Spectrometers at Nuclear Science Centre, New Delhi S. Nath, A. Jhingan, T. Varughese, J. J. Das, P. Sugathan, N. Madhavan, R. Kumar, R. P. Singh, S. Muralithar, R. K. Bhowmik, and A. K. Sinha pp. 1523-1527 Full Text: PDF (176 kB) The Characteristics of the Halo Neutron Preemission in the Fusion of 11Li with Light Targets M. Petrascu pp. 1528-1535 Full Text: PDF (167 kB) New Neutron Magic Number N=16 for Neutron-Rich Nuclei Z. Dlouhý et al. (for GANIL-Orsay-Dubna-Rez-Bucharest Collaboration) pp. 1536-1543 Full Text: PDF (186 kB) Resonance States of Hydrogen Nuclei 4H and 5H Obtained in Transfer Reactions with Exotic Beams G. M. Ter-Akopian, D. D. Bogdanov[dagger], A. S. Fomichev, M. S. Golovkov, Yu. Ts. Oganessian, A. M. Rodin, S. I. Sidorchuk, R. S. Slepnev, S. V. Stepantsov, R. Wolski, V. A. Gorshkov, M. L. Chelnokov, A. A. Korsheninnikov, E. Yu. Nikolski, I. Tanihata, F. Hanappe, T. Materna, L. Stuttge, and A. H. Ninane pp. 1544-1551 Full Text: PDF (216 kB) Collective Excitations of the Element Z=120 S. Misicu, T. Bürvenich, T. Cornelius, and W. Greiner pp. 1552-1556 Full Text: PDF (133 kB) Binding Energies of Even–Even Superheavy Nuclei Z. Ren pp. 1557-1560 Full Text: PDF (103 kB) Manifestation of Shell Effects in Quasifission Reactions E. A. Cherepanov and V. V. Volkov pp. 1561-1568 Full Text: PDF (666 kB) On Search and Identification of Relatively Short-Lived Superheavy Nuclei (Z=>110) by Fossil Track Studies of Meteoritic and Lunar Olivine Crystals V. P. Perelygin[dagger], Yu. V. Bondar, R. Brandt, W. Ensinger, R. L. Fleischer, L. I. Kravets, M. Rebetez, R. Spohr, P. Vater, and S. G. Stetsenko pp. 1569-1573 Full Text: PDF (123 kB) Nuclear Mean Field from Chirally Symmetric Effective Theory A. Staszczak pp. 1574-1577 Full Text: PDF (120 kB) Application of the Program LISE to Fusion–Evaporation O. B. Tarasov and D. Bazin pp. 1578-1581 Full Text: PDF (213 kB) New Mechanism for the Production of Extremely Fast Light Particles in Heavy-Ion Collisions in the Fermi Energy Domain A. S. Denikin and V. I. Zagrebaev pp. 1582-1585 Full Text: PDF (136 kB) Multidimensional Langevin Approach to Description of Near-Barrier Heavy-Ion Fusion and Deep-Inelastic Collisions M. A. Naumenko, A. S. Denikin, and V. I. Zagrebaev pp. 1586-1589 Full Text: PDF (219 kB)Archived web conten

    Indications of transbronchial needle aspiration

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    Les ponctions par voie transbronchique se sont considérablement développées avec l’avènement de l’échographie endobronchique qui permet de mieux guider les prélèvements. La démarche diagnostique des nodules ou des lésions pulmonaires périphériques soulève toujours des controverses. Dans cette indication, l’échographie endobronchique combinée à la ponction transbronchique (ou à d’autres techniques de prélèvement), a un rendement diagnostique supérieur à la bronchoscopie souple traditionnelle, indépendamment de la taille de la lésion ; de plus, cette technique est sûre. L’évaluation tissulaire des ganglions médiastinaux est souvent requise dans le staging du cancer bronchopulmonaire et l’échographie endobronchique donne d’excellents résultats et est complémentaire de l’échographie oesophagienne. Elle est d’un apport diagnostique intéressant dans d’autres atteintes malignes ou bénignes (sarcoïdose) des ganglions médiastinaux ou hilaires. Cette technique devrait diminuer le recours aux explorations médiastinales chirurgicales

    Pathological Diagnosis

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    Lung volume reduction for severe emphysema: do we need a scalpel or a scope?

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    Resectional lung volume reduction has proven to be superior to medical treatment in reducing dyspnoea and in increasing lung function, survival and quality of life in a very well selected, low risk group of hyperinflated patients with heterogeneous emphysema predominantly in the upper lobe. Nevertheless, this intervention is hampered by an important pulmonary (30%) and cardiovascular (20%) morbidity, mainly as a result of prolonged (>7 days) air leak, and a 5% risk of death as a result of the surgical intervention. Results from ongoing randomised trials are awaited in order to determine whether less invasive, non-resectional lung volume treatment of emphysema via the bronchoscope using endobronchial valves, airway bypass stents or biological adhesives/heated water vapour will yield similar improvement with less morbidity and reduced mortality, compared with surgical resection. Furthermore, it is hoped that endoscopic lung volume reduction techniques may help patients with homogeneous emphysema currently excluded by most teams for the resectional procedure

    Adverse effect of hyperinflation on parasternal intercostals

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    SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Mechanics of parasternals and triangularis sterni in upright vs. supine dogs

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    SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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