1,409 research outputs found
Rana Plaza, Six Years On: We Will Not Shop Where We Cannot Struggle
On the sixth anniversary of the Rana Plaza disaster, Alessandra Mezzadri, a Senior Lecturer at SOAS, London, and author of The Sweatshop Regime: Garment, Exploitation and Labouring Bodies 'Made in India’, discusses the progress - or lack of - when it comes to garment workers’ rights and how we can help support workers
Internet e la glottodidattica
testo per il modulo Glottodidattica e tecnologie, per il Master Itals dell'Università Ca' Foscari V
Trattamento di ciglia ectopiche nel cane tramite l’utilizzo di fresa palmare a batterie (Algherbrush)
Five cases of histiocytic disorder in golden retriever dogs
Purpose: To report the clinical and histopathological aspect of ocular histiocytic lesions in five Golden Retriever dogs. Methods: Three cases of conjunctival proliferative lesions and two cases of conjunctival proliferative lesions associ- ated with the presence of cutaneous nodules, in five Golden Retriever dogs aged between 11 months and 3 years are reported. A complete ophthalmological examination was performed on all subjects showing conjunctival chemo- sis associated with the presence of nodular lesions in the bulbar and palpebral conjunctiva of the third eyelid; in two subjects the presence of nodules in the skin was also ob- served. Surgical biopsy of lesions, both ocular and cutane- ous, was taken in all dogs and specimens were submitted for histology.
Results: In four subjects histological findings were consist- ent with systemic histiocytosis while in one dog histology was suggestive of histiocytic proliferative lesion. One case presented, histologically, with marked angiotropic and an- gioinvasive organization of infiltrating histiocytes. This pa- tient died 6 months after the first presentation.
Conclusions: Histiocytic proliferative disorder should be considered as differential diagnosis in Golden Retriever dogs that present with nodular conjunctival lesions
UVEAL MELANOMA ASSOCIATED WITH NEVUS OF OTA IN A GERMAN SHEPHERD
Purpose: To describe clinical and histopathological findings of an uveal melanoma associated with
nevus of Ota in a dog. Methods: A 4-year-old, male, German Shepherd dog, was presented with a
three-day history of ocular pain in the right eye. Anamnesis reported facial skin pigmentation on the
right side since puppyhood. Ophthalmological examination revealed diffuse corneal edema, vascular
scleral congestion, diffuse iris iperpigmentation, iris bombè, and discoria; intraocular pressure was
41mmHg. Ipsilateral facial skin was diffusely hyperpigmented. Left eye did not show abnormalities.
Right eye ultrasonography showed severe iris thickening. Due to clinical signs, enucleation was
performed and the globe was submitted to histological examination. Preoperative thoracic
radiography and abdominal ultrasonography were declined by owners. Results: Histologically,
anterior uveal architecture was effaced by an infiltrating neoplasia, with transcleral extension to
surrounding orbital tissues. Pleomorphic, polygonal to spindle, neoplastic cells were organized in
nest or pseudorosettes. Intracytoplasmic melanin granules were occasionally visible. Mitoses ranged
from 0 to 9/HPF (IM 4.4). Anterior uveal melanoma was diagnosed. The dog died because of
pulmonary metastases two months after enucleation. Conclusion: Nevus of Ota is an oculodermal
melanocytosis characterized by accumulation of melanocytes in the ocular and cutaneous tissues
corresponding to the distribution of the ophthalmic and maxillary branches of the trigeminal nerve.
Human patients showing oculodermal melanocytosis are at increased risk of developing uveal
melanoma, as well as melanoma of the ipsilateral skin. To the authors’ knowledge, this is the first
report of an uveal melanoma associated with nevus of Ota in a dog
Surgical treatment of canine and feline descemetoceles, deep and perforated corneal ulcers with autologous buccal mucous membrane grafts
Objectives: To report the surgical technique and postoperative outcome of corneal repair with autologous buccal mucous membrane grafts in dogs and cats with descemetoceles, deep corneal ulcers, and perforated corneal ulcers with or without iris prolapse. Animal studied: Twelve cats (13 eyes) and fourteen dogs (14 eyes) were treated. Procedures: Grafts were harvested from the unpigmented superior labial mucosa using a biopsy punch. The corneal lesion was carefully debrided and cleaned. The graft was secured to the healthy cornea with a combination of simple interrupted and continuous 9–0 polyglycolic acid sutures. In 25/27 treated eyes, an overlying pedicle conjunctival graft was also performed. A temporary nictitating membrane flap was used in all cases. The pedicle conjunctival graft was trimmed about 10–20 days postoperatively. The median follow-up period was 549.2 days (range 14–2691 days). Results: No surgical intra-operative complications were observed. The ulcers healed and the integrity of the globe was restored in 24/27 treated eyes. Different grades of corneal fibrosis and/or vascularization and/or pigmentation were observed in all cases at the long-term follow-up. In two cases, enucleation was performed due to postoperative complications and one animal developed phthisis bulbi. A total of 22/27 treated eyes appeared to have regained effective visual function at the last clinical evaluation. Conclusions: Autologous buccal mucous membrane grafts appear to successfully manage severe corneal ulcers in dogs and cats, providing a useful and economical alternative to other corneal grafts
Trattamento della trichiasi palpebrale nel cane e nel gatto con iniezione intradermica di acido ialuronico
Introduzione e scopo del lavoro: riportare i risultati clinici ottenuti nel trattamento della trichiasi palpebrale con l’utilizzo di iniezioni intradermiche di acido ialuronico al 2,4%, nel cane e nel gatto. Materiali e metodi: studio retrospettivo su cani e gatti affetti da trichiasi palpebrale trattati con iniezione intradermica di acido ialuronico al 2,4% in alternativa alla chirurgia tradizionale, a causa di gravi malattie sistemiche concomitanti o mancata autorizzazione del proprietario all’anestesia generale. Solo negli animali aggressivi o molto agitati si è proceduto a lieve sedazione. Sui soggetti non sedati è stata applicata una crema anestetica sulla cute palpebrale. L’acido ialuronico è stato iniettato nel volume sufficiente a ottenere la scomparsa della trichiasi (volume massimo 0,6 ml).
Risultati: Sono stati trattati 23 animali (4 gatti e 19 cani), per un totale di 34 occhi. Non sono state osservate reazioni avverse sistemiche in conseguenza al trattamento effettuato; a livello locale tutti i soggetti hanno manifestato lieve iperemia, edema ed ecchimosi. Al follow-up a breve termine (30 giorni post-trattamento) 22/23 animali hanno mostrato la completa remissione della trichiasi e dei sintomi clinici associati. Si è osservata recidiva della trichiasi in 3/13 casi nei quali era disponibile un follow-up superiore a 6 mesi.
Discussione: L’iniezione intradermica di acido ialuronico rappresenta una possibile alternativa terapeutica non invasiva alla risoluzione chirurgica della trichiasi, specialmente nei pazienti con elevato rischio anestesiologico. Non può, però, essere considerato un trattamento definitivo in quanto con il riassorbimento del filler la trichiasi può recidivare, in particolare nel gatto.Introduction and aim of the study: to report the clinical outcome of trichiasis treatment by intradermal injections of 2,4 % hyaluronic acid in dogs and cats.
Materials and methods: retrospective study on dogs and cats affected by eyelid trichiasis treated with intradermal injection of 2.4% hyaluronic acid. The procedure was used as an alternative to conventional surgery because of severe concomitant systemic diseases or refusal to general anesthesia by the owners. Mild sedation was needed only in aggressive or restless animals. Application of a topical anesthetic cream to the eyelid skin was performed on non-sedated animals. Hyaluronic acid was injected in a volume sufficient to obtain the disappearance of trichiasis (maximum volume 0.6 ml).
Results: twenty-three animals (4 cats and 19 dogs) were treated, for a total of 34 eyes. No systemic adverse reactions were observed as consequences of the treatment. All subjects showed locally mild hyperemia, edema and ecchymosis. At the short-term follow-up (30 days post-treatment) 22/23 animals showed complete remission of trichiasis and associated symptoms. Recurrence of trichiasis was observed in 3/13 cases in which a follow-up of more than 6 months was available.
Discussion: intradermal injection of hyaluronic acid represents a possible non-invasive therapeutic alternative to conventional surgical resolution of trichiasis, especially in animal patients with high anesthesiologic risk. However, the procedure cannot be considered a definitive treatment because trichiasis could recur at the reabsorption of filler, particularly in cats
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