482 research outputs found
PCNA-negativity in the telencephalon of adul female songbirds (Serinus serinus): absence of signs of normal proliferation
No full textIn a recent study, we demonstrated the persistence of normal proliferation in the telencephalon of adult male songbirds (Serinus serinus), as shown by the expression of Proliferating Cell Nuclear Antigen (PCNA), a test that uses monoclonal antibodies to reveal cells in the S phase. Near the start of the breeding season, this proliferation was observed in circumscribed areas of the ventricular ependymal epithelium (zona germinativa dorsalis and zona germinativa ventralis) and in small masses of cells that were grouped or separated ("hot spots"). Therefore, we decided to extend this research to normal adult females of the species, using the same marker and the same time period as in the previous study. This time, however, we did not observe PCNA-positivity, and thus any sign of natural proliferation, in the telencephalic areas that showed it in the male songbirds. The immunocytochemical patterns recorded in females and males of Serinus serinus agree with the information reported in the literature, namely that in adult homeothermic Vertebrates the presence of spontaneous cerebral neurogenesis is limited to male songbirds
The Oral-facial-digital type I syndrome: a model to study renal cystic disease in ciliopathies.
No full textPh.D in Molecular Medicine ciclo V/XXI.
Anno academico 2010-2011
Many-valued logic: beyond algebraic semantics
No full textEditorial for the special issue on "Many-valued logic: beyond algebraic semantics
Journal of Logic and Computation, special issue on "Applications of Topological Dualities to Measure Theory in Algebraic Many-Valued Logic"
No full textIron-based reversible adhesives: Effect of particles size on mechanical properties
No full text A hot melt adhesive – mainly used for bonding plastic component in automotive field – was modified with different iron-based particles to give it a reversible behaviour. Mechanical and physical properties of these reversible adhesives were experimentally assessed in the work. The modified adhesives, coupled with electromagnetic induction, are able to guarantee separation of the joints without any damage to the substrates for recycling, reuse or repairing of components. Single lap joint specimens were prepared using epoxy/glass fibres substrates and tests were carried out on neat and modified adhesive with 5% weight of iron and iron oxide. Three different Fe particles size were tested: 450 µm, 60 µm and 1–6 µm. The particles size of iron oxide was 50 nm. Separation was studied using single lap joint specimens under electro-magnetic induction. Experimental results showed that the maximum peak load decreases when the average particles sizes increase. The peak loads of the smallest particles were equal to the ones of the pristine adhesive. The elongation of the adhesives increases when the adhesive is modified with both iron and iron oxide particles. Finally, experimental tests on single lap joints coupled with electro-magnetic induction showed that separation of the substrates is possible using iron oxide particles. Electro-magnetic tests conducted on particles alone, helped to understand that bigger particles are able to overcome the melting temperature of the adhesive but hot-melt adhesives modified with these particles are not able to reach the melting. These tests showed that the number of particles into the adhesive matrix is very important for this kind of tests. </jats:p
LE NOTIFICAZIONI CIVILI NELLA RIFORMA CARTABIA
No full textIn civil proceedings service by certified electronic mail is developing to such a point that, in a very large number of cases, it has become mandatory for lawyers when the recipient is obliged to have a digital domicile (e.g. companies, or persons registered in professional registers) or when, even without being obliged to do so, a person (including a natural person) has
elected his or her own digital domicile registered in a special public directory. The article provides a critical evaluation and interpretive analysis of the new
rules introduced by the so-called Cartabia reform on a topic of such particular interest to highlight its strengths, weaknesses, contradictions, inconsistencies and/or other important issues. The author comes to the conclusion that the objective of exclusively electronic notifications can only be achieved when a general obligation of digital domiciliation for all citizens is established, which is still missing. To achieve this result, however, it would be necessary to adopt suitable solutions to sanction overloading of the certified mailbox
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